Friday, November 2, 2007

Ovo treba prevesti na srpski molim, pod hitno!

References and comments:

V2004. ** 'Medicinal' GM crops produced **
Scientists have genetically engineered plants to produce health-promoting substances usually found in fish.

V2004. ** Smart homes offer a helping hand **
The homes of the future could be filled with clever technology designed to help you live your life.

V2004. ** Could a pill prevent grey hair? **
Scientists identify genes that may play a role in turning hair grey, raising hopes of new treatments.

V2004. ** Too young for school? **
The BBC's Mike Baker wondered whether young children are pushed into formal learning too soon - so he asked some.

** Material girl bends over backwards **
Madonna's amazing fitness and flexibility is a good example to us all and can be achieved through simple exercise.

VI 2004. *Effective anaesthesia 'guaranteed'*

New technology will end the fear that patients will wake up during

VI2004.** Human embryo cloning considered **
The first request by British scientists to clone human embryos has been discussed by experts.

VI2004. a friend

** Message **
I should be frozin some of my healthy ovarian tissue....who knows maybe in 50-60 years, when human life is much extended, I wanna want to have a child...
** Ovary transplant pregnancy first **
A woman has become pregnant following an ovarian tissue transplant in a fertility breakthrough, it has emerged.

VII2004. ** Uniforms for all in school reform **
England's secondary schools are urged to adopt uniforms and house systems as they become "independent specialists".

VII2004. ** Stem cells 'treat heart attacks' **
A transplant of bone marrow stem cells can aid recovery from a heart attack, researchers find.

VII2004. ** Gene mutation linked to diabetes **
A natural fault in a newly discovered gene is a major contributor to type 1 diabetes, say US scientists.

Name: mima
> Email:
> Comments: where is those page about the rats that you had, so you wrote
their lives and how they died?
> Hi, Mima, it's now all been moved into the community section, under member's

rats do get stoned research /paghat/

** Viewpoints: Abortion **
BBC News Online asked eight commentators for their views on abortion.

** World trade deal 'within reach' **
Marathon talks continue in Geneva on liberalising world trade, amid signs that they may be making some progress.

VIII 2004. ** Cell swap could help conservation **
Japanese scientists have developed a new kind of assisted reproduction for animals, in which one species can create another.

** Nature 'mankind's gravest threat' **
Giant tsunamis, super volcanoes and earthquakes could pose a greater threat than terrorism, scientists claim.

** Farm changes 'behind wasp plague' **
New eco-friendly ways of farming could be causing a steep rise in the UK's wasp populations, an expert has said.

** Scientists given cloning go-ahead **
The first request by British scientists to clone human embryos has been granted by experts.

** Space lends hand to stem cell study **
UK tissue engineering experts are teaming up with NASA to find treatments for diseases back on Earth.

** Oh, purr-lease **
As the Daily Telegraph launches pet obituaries, here are some other ways to part with hard-earned cash to benefit your furry sidekick.

** Hungry world 'must eat less meat' **
People will need to eat more vegetables and less meat because of dwindling water supplies, scientists say.

** Medicine hope for psychedelic drugs **

** Teleportation goes long distance **
Physicists have successfully teleported particles of light over a distance of 600m across the River Danube in Austria, the journal Nature reports.

I did not know Sweeden ii sunny

hoteli u Bg






7.VIII 2004. give the voice

14.VIII 2004. nice

20. VIII 2004. emergency contraception


28.VIII 2004.** Water 'wake-up call' given by UN **
A UN report says key goals to improve clean water and sanitation by 2015 will fail unless the world acts.

31.VIII2004. ** Scepticism over cloning from dead **
Experts cast doubt on claims that a scientist has made embryos from dead people's tissue.

7.IX2004. ** Modified animals continue trend **
The use of genetically modified animals in UK labs continues to grow, official statistics released on Tuesday show.

7.IX.2004. ** Viewpoint: Animal rights **
As the number of animals being used for research experiments in Britain rises, BBC News Online asks five commentators for their perspective on the issue of animal rights.

9.IX2004. ** Phone radiation openness demand **
It should be easier for mobile users to discover the amount of radiation generated by their handsets, a leading expert says.

9.IX2004. ** Pollution harms developing lungs **
Children in smoggy areas have retarded lung development which puts them at risk of diseases, say researchers.

some of these we have /mimaradio/:

10.IX2004. ** Clinical drug trials 'distorted' **
More openness is needed over clinical drug trial results to stop them being distorted, leading medical journals say.

10.IX2004. ** Cannabis study encouraging for MS **
A big UK study of cannabis-based drugs has shown evidence for a long-term benefit in easing multiple sclerosis symptoms, scientists say.

10.IX2004. ** Hypnosis 'reduces cancer pain' **
Childhood cancer patients suffer less pain when placed under hypnosis.

10.IX2004. ** Waging war on the super rats **
Scientists go back to the drawing board in their battle against poison resistant rats.

10.IX2004. ** Rats help sniff out TB **
Rats are being trained to detect tuberculosis samples in a project which could help the developing world fight the disease.

13.IX2004. ** Europe urged to embrace GM foods **
A conference on genetically-modified crops opens in Germany with calls for Europe to take up GM foods.

13.IX2004. ** Positive attitude delays ageing **
You may not be as young as you feel, but research has found that a positive attitude may delay the ageing process.

13.IX2004. ** 'UK must lead on climate change' **
Michael Howard accuses Tony Blair of squandering the chance to lead efforts against climate change.

14.IX2004. ** Beauty spot given a green boost **
A turf roof and solar slates are just two of the green innovations used to revamp buildings at one of Cornwall's most spectacular locations.

14.IX2004. ** Media spotlight on Baghdad deaths **
Two very different accounts emerge about the bloody and graphic events in the Iraqi capital's Haifa Street on Sunday.

14.IX2004. ** Micropower 'could fuel UK homes' **
Household-scale renewable energy schemes could provide power for many British families, conservationists say.

16.IX2004. ** Brazil embraces sustainable idea **
Sue Branford visits an environmental project deep in the Amazon which has turned a revolutionary idea into reality.

19.IX2004. ** The greening of Ground Zero **
Skyscrapers that power themselves through wind and solar energy collected on their roofs are named in the winning designs in a competition aimed at creating a greener modern city.

20.IX2004. ** UN summit to tackle world hunger **
World leaders prepare to meet at the UN in New York to discuss ways of alleviating hunger and poverty.

21.IX2004. ** The battle for DR Congo's wildlife **
As donors pledge $40m to save DR Congo's wildlife, life in Virunga Park remains a battle ground.

22.IX2004. ** The deafening sound of the seas **
The crescendo of noise in the oceans is interfering with marine mammal communication, campaigners say.

23.IX2004. ** Looking to the hydrogen horizon **
Demand for oil is soaring, and with it the price - currently $46 a barrel. But some experts believe hydrogen cars could offer the solution to a difficult fix.

24.IX2004. ** Support for UN reform increases **
Support is growing for a bid by four influential countries for more permanent seats on the UN Security Council.

24.IX2004. ** Dogs 'sniff out' bladder cancer **
Dogs can be trained to sniff out bladder cancer, scientists say they have proven for the first time.

26.IX2004. ** Sea defences 'raise floods risk' **
Building sea defences could increase the risk of flooding in coastal areas of England and Wales, a report claims.

26.IX2004. Why someone has immunity and someone does not? Immunity for all or for noone!
** Gaddafi son 'in Paris car chase' **
A car chase in Paris involving a son of Libyan leader Muammar Gaddafi leads to a scuffle with police, sources say.

27.IX2004. ** Message **
DU was in bombs sent troughout the Srbija.
Very upset I am.
** Gulf war health checks 'too late' **
Tests to detect uranium in the bodies of Gulf war soldiers are 14 years too late, say veterans.

27.IX2004. ** UK launches £10m recycling effort **
The UK government launches a £10m multi-media advertising campaign to encourage the British public to recycle their waste.

28.IX2004. in France, i think they are concurents to Noos.
for 60 euros...

29.IX2004. with what I color my hair

3.X.2004. ** Message **
Sick, sick, sick and sad this ‘watch list’.
** Stars protest over terrorism list **
Robin Williams and Paul Simon are joining other stars in a show to protest against the US Government's terrorist "watch list".

read this thread

4.X.2004. ** Introduction: Planet under pressure **
BBC News Online's Alex Kirby introduces a six-part series on the some of the most pressing environmental issues facing the human race today.

4.X2004. ** Lennon killer petition hits 3,000 **
An online petition by John Lennon fans opposing parole for killer Mark Chapman gets more than 3,000 signatures.

6.X2004. saddest thing in the world ** Biodiversity: The sixth great wave **
The Earth's growing human population is leaving less room for other species, many of them vital to our survival, writes Alex Kirby.

6.X2004. ** Srebrenica Muslim chief on trial **
A Bosnian Muslim commander who headed Srebrenica's defence is in court over the killing and torturing of civilians.

6.X2004, here it is what i was looking for. read carefully, please.

also, check:

7.X.2004. ** Teflon's sticky situation **
It's on saucepans, clothing, even buildings, but now Teflon - the famed non-stick chemical - is at the centre of a slippery controversy about cancer and birth defects.

7.X2004. ** Message **
Everyone should be revived, always!!!
** Ill baby 'should not be revived' **
A judge rules a seriously ill premature baby should not be revived if she stops breathing.

9.X2004. pack rats-interesting

9.X2004. read this, please or here:

11.X2004. Antibiotics are necessary when lots of sugar and carbs comes into our organism is that true?
** Antibiotic can 'turn off cancer' **
A common antibiotic is able to turn off cancer cells in mice, offering hope of new treatments, say researchers.

11.X2004 ** Message **
Organic, only organic!!! French AB sticker for whole world /AB means Agriculture Biologique/.
** Pollutants 'in children's blood' **
Environmental campaigners are warning potentially dangerous chemicals are present in children's blood.

11.X2004. ** Climate fears on sharp CO2 rise **
A sharp rise in carbon dioxide in the atmosphere raises fears global warming is speeding up, reports say.

13.X2004. may be important ** Targets 'hamper recycling effort' **
UK government policy works against efforts to improve the nation's recycling record, a report says.

14.X2004. ** Carbon 'reaching danger levels' **
The UK government's top scientist says atmospheric carbon dioxide concentrations are now becoming dangerous.

14.X2004. ** Viewpoints: Countryside Matters **
As part of News Online's coverage of rural life in Britain, we polled the views of some of the key players.

14.X2004. ** Right to silence? **
The infuriating ring of someone else's mobile blights many visits to the cinema or theatre. France has decided to block the signals - could the UK follow suit?

15.X2004. /We do not need wrinkle creams. Only white of fresh AB egg can help us out when applied directly. Also vegan food without salt is the key. Also, more than five ingredients in a cream is more than a mixture/
** British 'use less wrinkle creams' **
UK women are less likely to use anti-wrinkle creams than other western European women, research suggests.

15.X2004. /would like discussion about this/ : ** Security under the skin **
A US company has been given the green light to implant microchips in humans. It's intended to provide medical information ... but will it turn into a surveillance system?

15.X2004. to show us whats good for humans... rats and bambus/

15.X2004. ** UK chemists seek hydrogen store **
Newcastle and Liverpool University teams take a major step forward in making hydrogen a practical replacement for petrol.

15.X2004. ** Global amphibians in deep trouble **
Almost a third of the world's amphibian species are confronted by the prospect of extinction, naturalists say.

16.X2004. /Biomass makes huge pollution and uses the land otherwise could be used for agriculture/.** UK boost for biomass fuel crops **
The UK government is stepping up efforts to stimulate the growing of crops for use in generating renewable energy.

16.X2004. /important/ ** WTO sugar ruling sparks EU appeal **
The EU is to appeal against a World Trade Organisation ruling that its sugar subsidies breach world trade rules.

20.X2004. /crucial livehood risk/ : ** Water scarcity: A looming crisis? **
The Earth's growing human population is leaving less room for other species, many of them vital to our survival, writes Alex Kirby.

20.X2004. ** Aid agencies' warning on climate **
Climate change threatens to undo the world's attempts to eradicate poverty, a coalition of aid agencies warn.

20.X2004. It would be great to close him in proper space and feed them AMI cat food.
** Toothache 'made lion eat humans' **
Experts believe a sore tooth may have led a Tanzanian lion to go on a human killing spree instead of hunting buffalo.

20.X2004. /I love them and their professionalism/: People for Ethical Treatment of Animals

20.X2004. /The situation in West Bank must be lawfully solved/: ** Ugly war over West Bank olive crop **
An ugly land war is raging between Palestinian olive growers and Jewish settlers in the West Bank.

21.X2004. Warning on internet health advice :

21.X2004. /I do not like a mouse trap. It could hurt the mice/:
** Those eureka moments **
The inventor's lot is a hard one. Months of work on an idea are often followed by the realisation that nobody is interested. But are inventors about to buck the trend?

21.X2004. Designer baby cured its sibling:

23.X2004. /environmental refugees/:
** Message **
I believe that Geneve Convention about refugees needs to include environmental refugees. I do expect mass migration in that sense, though, but its inevitable. Concerning this case, if I am a Japanese, I would want to live somewhere calmer, and more others would, certainly.
** Powerful earthquakes shake Japan **
At least one person dies and more than 70 are injured in a series of earthquakes in northern Japan.

23.X2004. /In magasine Scientific American was declared that we ought to be living 125 years/: Longevity needs to be expected: ** Humans 'will live to age of 150' **
Human beings will live would die at between 30 and 40 years old if they did not live in social groups, research finds.

23.X.2004. /The world should stop with aspartame usage and production alltogether/: Toxicity of aspartame from Parkinson disease site :

25.X2004. /Very suuspicious about this one/: ** Can a little radiation be a good thing? **
Some experts believe a little radiation may actually be good for you. BBC News Online investigates.

25.X2004. /They need the Vermicast canalisation/: ** The unsung heroes of Wajir **
The men who collect human excrement with buckets in a north-eastern Kenyan town.

25.X2004. Vermicast canalisation:

25.X2004. ** Quiz: World water crisis **
You drink it, wash in it and flush the toilet with it every day. But how much do you appreciate the finer points of the liquid that sustains life?

25.X2004. /It is unlawfull to take people outside their country for interrogation/:
** CIA 'took detainees out of Iraq' **
US intelligence officers have taken detainees out of Iraq for interrogation, The Washington Post reports.

25.X2004. /We should pass on hemp usage instead of cutting trees/: ** Life-giving dead wood 'at risk' **
Dead and dying trees essential for many other forms of forest life are in short supply, conservationists say.

26.X2004. /Adult stem cells are the future and keep big promisses/:
** Stem cells 'could restore vision' **
Stem cells taken from the eye could help restore normal vision in people with sight problems, researchers say.

29.X2004. /Stem cells from adult should be used/: ** Abortion row fears over eye cure **
The restoration of a blind woman's sight using foetal tissues is likely to spark ethical debate, say scientists.

29.X2004. /Let Iraqi people be refugees in the country of their choice, paid for installation and formation by ‘the coalition forces’/: ** Iraq death toll 'soared post-war' **
Poor planning and coalition air strikes have led to more than 100,000 extra civilian deaths in Iraq, scientists find.

30.X.2004. ** 'Smelly' mates guide seabirds **
Seabirds called prions, which mate for life, find their nests by sniffing out their partners, scientists say.

30.X.2004. ** Eton or the zoo? **
The discovery of a new species of human poses exciting questions about who we are. How would we treat this close relative if one were found alive? Anthropologist and author Desmond Morris writes.

31.X2004. ** Summit on eco-friendly buildings **
A city which has embraced the concept of eco-friendly housing hosts the International Earthship Conference.

1.XI2004. ** Message **
who is HFEA? We need one names for all languages for the world organisations.
** Embryos to be screened for cancer **
Scientists are granted permission to screen test tube embryos for an inherited form of bowel cancer.

1.XI2004. ** Support sought for CO2 storage **
UK environment minister Elliot Morley is to ask leading industrial nations to support a plan for storing carbon dioxide under the sea bed.

3.XI2004. ** Message **
caffeine alone is not good for arteries... Do you hear it? I don't want you that in 10-20 years time you have cardiovascular problems???
** Vices 'combine' to harm the heart **
Smoking and drinking coffee act together to have a harmful effect on arteries and blood flow, say researchers.

3.XI2004. /They should build more hospitals near by/: ** Cambodia's health lottery **
One outstanding hospital in Cambodia is so popular that it has had to introduce a lottery in order to choose patients.

3.XI2004. ** Light up my life **
With the clocks going back, millions of British workers will be heading home this evening in the dark. Depressing? Yes, but there could be a good reason for why we get the winter blues.

10.XI2004. /Only by solar energy and wave power/: ** Energy: Meeting soaring demand **
The BBC's Alex Kirby looks at the challenge of providing the world with energy without damaging the environment.

30.X2004. /Hope they survived. Does salt and sugar in food promote the chance of conjoined twins?/: ** Doctors fear for Tanzanian twins **
Doctors say the lives of conjoined twins in Tanzania is in jeopardy because their lungs cannot expand.

30.X2004. /Poor rats. They should be dealt with with more respect as they are saving lifes of billions of people as the medicaments were first tried on them/: ** Mexico rats survive cat onslaught **
Health officials in the Mexican state of Chihuahua fail to deal with a rat plague by sending in hundreds of cats.

30.X2004. /WHole world should do the same, or even better, stop producing plastic bags and give for free reusable bags in supermarkets/: ** Scots count cost of plastic bags **
Scots DIY enthusiasts will now pay for plastic bags as a big chain tries to cut pollution.

13.XI2004. /We need less beer and more food/: ** Brewer offers new health warning **
Britain's biggest brewer - Scottish Courage - will be labelling its bottles and cans of beer with a health warning.

13.XI2004. /Why they had problems with him defending himself alone?/: ** Delays plague Milosevic's trial **
Journalist and author Chris Stephen takes a look at how trial of Slobodan Milosevic has dragged on in The Hague.

15.XI2004. listen for the serbian djs on this page

15.XI2004. /Environmental refugees they need to become/: ** Bhopal 'faces risk of poisoning' **
Thousands of Indians around Bhopal are still at risk of poisoning 20 years after a gas disaster, a BBC probe reveals.

15.XI2004. /This is interesting. I wonder where is the location of Atlantida/: ** New claim on location of Atlantis **
US researchers claim to have found evidence locating the lost kingdom of Atlantis off the coast of Cyprus.

16.XI2004. Project schoolyard USA :

17.XI2004. ** Ozone 'link' to premature deaths **
High ozone levels may be killing off city-dwellers around the world, experts suspect.

17.XI2004. /We should all pass on hydrogen fuelled cars like Prius/: Hybrid Prius

18.XI2004. ** Cocaine users' brains 'different' **
Cocaine users' brains have a different structure that could affect their judgement, a study suggests.

19.XI2004. bioprogress :

20.XI2004. /I heard there is in Israel club of over 100 years old and there are two 119 year old ones. They should be able to remember all the lost ones whose graves do not exist for the cloning process/: ** World's oldest man dies aged 113 **
The world's oldest man, who gave up driving at 108 because "slow drivers annoyed him", dies at 113.

20.XI2004. ** Message **
Can our comps can go to grid to help Science?
** Computer grid to help the world **
Through the World Community Grid, your computer could help address the world's health and social problems.

20.XI2004. /They should have their own money in ration 1:1 to euro and dollar and shekel.../ ** Message **
Palestinians do not have even their moneta, they use shekels?
** Gaza's blocked arteries **
The BBC's Martin Asser takes a taxi ride through the Israeli-occupied Gaza Strip to sample the barriers to Palestinians' travel.

21.XI2004. Nice articles :

21.XI2004. ** Doctors' therapy 'slows ageing' **
Two doctors believe they have the cure for wrinkles - infra-red light therapy.


29.XI2004 /This is not the same as previous studies about GM crops, see Friends of Earth and Greenpeace webpages as well as WWF pages/: ** Study finds benefits in GM crops **
A major UK study of genetically modified plants finds no evidence that they harm the environment.

8.VIII2007. WWF:

8.VIII2007. Friends of Earth:

8.VIII2007. Greenpeace:

3.XII2004. ** Message **
Need to talk about this...with you.
** Ex-rebel leader elected Kosovo PM **
A former rebel commander who was questioned by war crimes investigators is voted in as Kosovan prime minister.

4.XII2004. /Thank you. Its a present, that news/: ** 'We will be able to live to 1,000' **
Cambridge University geneticist Aubrey de Grey believes that within the foreseeable future, human beings will be able to live to 1,000 years of age.

7.12.2004. /The war is illegal/: ** Letter: Military lawyers defend civil liberties **
Robert Hodierne, an editor of publications for the US military, examines how the war on terror affects civil liberties in the US.

7.12.2004. /Normal guy/: ** US deserter seeks Canada asylum **
A US army deserter seeks refugee status to stay in Canada, arguing the US-led war in Iraq is illegal.

8.XII2004. /It is called carbon dioxide/: ** Q&A: UK's carbon targets **
Our correspondent Richard Black explains the targets Britain is trying to meet on CO2 reductions.

9.XII2004. /They should go again through same papers to excuse themself by giving Roma peoples entry/: ** UK 'discriminated against Roma' **
The government discriminated against Roma people seeking entry into the UK, the Law Lords rule.

9.XII2004. Scientists pluck the details from chicken-genetics map
In a step forward for biology and agriculture, scientists yesterday unveiled the first, detailed analysis of the genetic blueprint of the chicken — revealing few surprises...
Full story:

9.XII2004. ** One in 10 families 'pays bribes' **
Ten per cent of people say they or a member of their household paid a bribe in the past year, a survey suggests.

9.12.2004. /What happened? I need follow up of the news BBC are giving/: ** Serbian church sues over Kosovo **
Serbia's Orthodox Church files a lawsuit accusing the UK, France, Germany and Italy of failing to protect churches in Kosovo.

10.XII2004. /Not with my ideas/: ** One billion 'denied a childhood' **
More than half the world's children face a brutal existence because of poverty, war and Aids, says Unicef.

12.XII2004 /New, by all accepted protocol we need/: Kyoto BBC:

14.XII2004. ** Europe's heatwaves 'soon routine' **
The heatwave which killed thousands in Europe in 2003 could soon seem cool, UK climate scientists say.

14/12/2004. /Everywhere in the world this should happen/: ** Countryside opens up to ramblers **
Thousands of acres of private land in the South open up to ramblers for the first time.

18.XII2004. /People need geohazard lessons to avoid this/: ** Freak storms kill six in France **
At least six people die and dozens are hurt as hurricane-strength storms hit Paris and much of northern France.

18.XII2004. ** Mars water tops science honours **
The discovery that salty, acidic water once flowed across the surface of Mars has topped a list of the 10 key scientific advances of 2004.

18.12.2004. ** Forecasters face losing key tools **
Microwave frequencies vital for Earth monitoring are being lost to commercial uses, weather forecasters say.

18.XII2004. ** Message **
please, talk with me about this. Do not understand what they are saying.
** Missile team homes in on the Moon **
A US firm is proposing to use guided missile technology to make a precision landing on the Moon.

18.XII2004. ** Bush stays course on environment **
US President George Bush was criticised by green groups over his environmental policy during his first term, and little is likely to change in the next four years.

Ouest France vendredi 17 décembre 2004
and everything from the ‘Amis de la Terre’ association /French site side/

22.XII2004. /Please use SI sitem of units/: ** World's smallest baby born in US **
The world's smallest surviving baby makes her first public appearance at a US hospital, alongside her slightly larger twin sister.

24.XII2004. /They should name the people if something like this took place/: Israelis stealing eyes of children from Palestina claim :

24.XII2004. ** Battling against Israeli 'apartheid' **
Adel Kaadan is an Israeli Arab who has been fighting for the last decade for the right to move to a Jewish suburb, reports the BBC's Lucy Ash.

24.XII2004. /All balls should be no leather ones/: ** Modern footballs 'not much safer' **
Heading a modern-day football is not significantly safer than an old-style leather ball, ballistics experts find.

26.12.2004. ** Rapper's message for France **
Caroline Wyatt talks to a rapper who is trying to reconcile his love for France and music with his adopted Muslim identity.

26.XII2004. ** Flu crisis 'could be contained' **
Scientists say antiviral drugs should be being stockpiled now in anticipation of a flu pandemic.

27.XII2004. New year’s celebration waste statistics

31.XII2004. Good choice, hard neverthless in earthquake:

1.I2005. ** New Year begins as world mourns **
Millions mark the start of 2005 with restraint amid global mourning for victims of the Asian earthquake.

1.I 2005. ** Romanian, 67, pregnant with twins **
Romanian doctors say a 67-year-old woman, pregnant with twin girls, is set to be the oldest recorded mother.

1.I2005. ** Message **
I don't think the hearing was the factor. Possibly pressure changes, temperature...
** Did animals have quake warning? **
The BBC's Sue Nelson investigates claims that wild animals, who escaped the impact of the quake, may have a sixth sense.

3.I2005. /The donations were pretty small concerning that still architectural projects with proper buildings are not built on that places. They need Tremble Michel walls with Vermicast canalisation and solar panels and photovoltaics and green areas in between the buildings/: ** Big pledges yield benefits for donors **
World leaders are realising that big donations for tsunami aid can yield political benefits, says the BBC's John Simpson.

3.I2005. ** Living life as Donald Duck **
How an octogenarian GP has coped sharing his name with one of Disney's most famous cartoon characters.

3.I2005. /People should stop drinking alcohol alltogether/: ** Alcohol hampers depth perception **
Drinking alcohol impairs driving ability by disrupting depth perception, researchers find.

3.I2005. ** Andaman aborigines' fate unclear **
The fate of some of the world's most primitive people in India's Andaman and Nicobar islands is unclear.

3.I2005. richest 578 milliarders

4.I2005. ** Criminals target tsunami victims **
The victims of the Asian tsunami now face a new danger - that of criminals and opportunists trying to cash in on their misfortune.

4.I2005. ** Message **
What the kids were doing outside?
** Israeli shell kills seven in Gaza **
Seven Palestinians are killed by Israeli army fire in Gaza, sparking furious words from leader Mahmoud Abbas.

4.I2005. ** Blogs take on the mainstream **
Blogs have shifted the balance of information online, argue experts, and they are here to stay.

4.I2005. American election fraud. I thought there was a fraud, but, until now did not find a word about it on media.

5.I2005. Tribes and earthquake in Asia. better report.

5.I2005. Worth reading. ** Tsunami man survives week at sea **
A tsunami survivor is rescued after floating on tree debris in the Indian Ocean for eight days, eating coconuts. BBC

5.I2005. ** Push to block Brazil dam project **
Tim Hirsch reports on moves by Brazilian environmentalists to prevent the destruction of a forest threatened by a dam. BBC

5.I2005. ** Physics goes in search of 'cool' **
Einstein Year is launched in the UK and Ireland to inspire the next generation of physicists. BBC.

5.I2005. ** Home Office cat history revealed **
The history of the Home Office cat revealed in documents handed over to the National Archive under the Freedom of Information Act. BBC.

6.I2005. ** Schizophrenia prediction possible **
Schizophrenia can be predicted in high risk groups years before psychosis sets in, say scientists. BBC.

6.I2005. ** Sorter weeds out less healthy sperm cells **
Scientists have developed a machine to separate out healthy sperm from that which is damaged and unlikely to be of use in IVF. BBC.

7.I2005. ** Antibiotics 'block nerve damage' **
Antibiotics including penicillin may help prevent nerve damage in a wide variety of neurological diseases, research finds. BBC.

7.I2005. ** TV's future in the hands of viewers **
With home theatre, plasma high-definition TVs, and digital video recorders, the way people will watch TV will be radically different in five years' time. BBC.

7.I2005. ** Message **
Why separate them? That is so bad, sad and unnecessary.
** Odd couple make friends in Kenya **
A baby hippo rescued shortly after floods last week befriends a 100-year-old tortoise in Kenya. BBC.

8.I2007. ** Poverty fight 'neglects science' **
Science and technology could do far more to end hunger and poverty than politicians realise, United Nations advisers say. BBC.

8.I2005. /I love his articles/: ** Copying, content and communism **
Regular columnist Bill Thompson is worried about what Microsoft thinks of him. BBC.

9.1.2005. ** Monsanto fined $1.5m for bribery **
Agrochemical giant Monsanto agrees to pay $1.5m in US penalties for bribing a high-level Indonesian official. BBC.

10.I2005. ** IT support for your parents **
As technology penetrates age barriers, and parents succumb to the benefits of the internet, their children are being called on as technical support. BBC.

11.I2005. Rats recognise different languages. Yahoo UK:

11.I2005. ** Tsunami man's two-week sea ordeal **
A 21-year-old Acehnese man is discovered out to sea two weeks after being swept away by the tsunami. BBC.

11.I2005. Rats laugh proof: or

12.I2005. ** Message **
What is this about? I am seek of such a treatment - why irrelevant?
** Marathon Milosevic trial resumes **
A French nurse testifies as the war crimes trial of ex-Yugoslav President Slobodan Milosevic resumes. BBC.

12.I2005. ** Message **
how American rice could be cgeaper than Italian in Europe?
** Italy's simmering rice threat **
The BBC's Mark Duff visits rice farmers and chefs worried about the threat to Italian rice from free trade agreements. BBC.

12.I2005. ** Drugs: Facts behind the fiction **
All the drama-documentaries in the IF series are based on rigorous journalism and research. Here are just some facts surrounding the issues of drug legalisation. BBC.

13.I2005. ** French test 'chemical castration' **
Doctors in France start givingchemical treatment to 48 repeat sex offenders to see if it will stop them attacking again. BBC.

13.I2005. narcotics discission BBC. /Discussion whether they should be legalised/:

15.I2005. wanted to watch: or




15.I2005. the eye of god: or

16.I2005. horses /and other animals/ and difficult diseases: BBC.

17.I2005. Spa similar to Igalo in Montenegro mud?

17.I2005. BBC article and photos :

17.I2005. loto double gain

18.I2005. female fertility testing:

18.I2005. male fertility testing:

18.I2005. French CMU /Couverture maladie universelle, should all people of the world be under this regime CMU/ :

18.I2005. cochin ivf treatments cout :

18.I2005. examens before seeking IVF

18.I2005. forum bebes:

18.I2005. UN development programme:

18.I2005. impot sur bourse stock market

18.I2005. printing organ in a day: ** Skin and bones 'made to measure' **
Scientists in Manchester develop new technology to "print out" human skin and bones.

19.I2005. Israeli virtual gallery:

19.I2005. facts and logic about Palestinian state: from them /Be sure to give us credit and 2. Be sure to send us copy of the book.Please confirm.Sincerely,Gerardo Joffe, President FLAME/

19.I2005. ** Dustmen sent to school after binning art **
Three refuse collectors are to be sent on an Art Appreciation Course after incinerating Frankfurt sculpture.

20.I2005. cutest foto in the world:

20.I2005. oooh, that beautiful animal intelligence... for mating:

20.I2005. Malki shampoo froim salty Sea has five ingredients within, unnecesary parfum as sixth: or

20.I2005. ** Why some people entice mosquitoes **
Scientists believe they have discovered the reason why mosquitoes find some of us more tasty than others.

20.1.2005. ** Message **
But read the last sentences...What a danger from outsider's diseases.
** Tsunami folklore 'saved islanders' **
Anthropologists say folklore helped to save the ancient tribes of the Andaman and Nicobar islands from the worst of the Indian Ocean tsunami, reports Subir Bhaumik.

20.I2005. ** Therapy hope for stroke victims **
Stimulating the brain with a magnet may be a good treatment for strokes victims, say scientists.

20.I2005. ** Message **
She needed to be on insulin if she is not already on it, or she needed to control herself constantly and give lots of correct insulin units. I blame the hospital for this. This was too risky for both. The child now risks diabetes and other methabolic diseases as he was producing insulin in too big quantities because his mother did not produce insulin. And that is why he has grown soo much. BBC, as usual, do not give the clear picture and do not stress how important it is to be glucose balanced and how dangerous this could be. Such a shame for medicals.
** Woman gives birth to 'giant baby' **
A Brazilian woman gives birth to a 17lb (8kg) boy, nicknamed the "giant baby" by doctors.

20.I2005. ** Message **
Just not now to wait a decade or more for the application of this technology...
** Plastics created from orange peel **
US scientists discover how to make plastics from orange peel, using the greenhouse gas carbon dioxide.

20.I2005. Srebrenica’s dead people are buried, six hundred of them.

Genocide in Rwanda from the year 1994:

20.I2005. The Centre for Peace in the Balkans , correspodance with them: The quote you use comes from The Times, 14 July 1995: Muslim soldiers 'failed to defend town from Serbs ' By Michael Evans, Defence Correspondent.

The Centre for Peace in the Balkans

This message is intended only for the use of the individual or entity to which it is addressed and contains information that is confidential and may be privileged. If the reader of this message is not the intended recipient, or the employee or agent responsible for delivering the message to the intended recipient, you are hereby notified that any dissemination, distribution or copying of this communication is strictly prohibited. If you have received this communication in error, please notify us immediately at and delete the original message.

-----Original Message-----
From: Mima Mijic []
Sent: Thursday, January 20, 2005 1:31 PM
Subject: Quite important

I am not sure whether you are talking srpski, so i should write in English.
I am writing a book and will say Serbian view of Srebrenica and give your
website a credit as well as this link

For the concisity reasons, could you please specify the sources of
information in this passage, or, if possible, clean it from the link page
because it does not have a named sourse so it could be taken as a matter
of conspiracy?

Thanks in advance. I shall send you a book when it's published (now I am
in phasis of collecting data and writing first drafts).

Best wishes and take care,
Mirjana Mijic

Here is the part I was talking about:

The abandonment of Srebrenica to a relatively small Serb advancing force
caused surprise in the West, especially after the largely Muslim
government army had demonstrated considerable infantry skills in recent
attacks. There were reports that up to 1,500 Serbs were involved in the
assault on Srebrenica, but intelligence sources estimated the main attack
was carried out by a force of about 200, with five tanks. "It was a pretty
low-level operation, but for some reason which we can't understand the BiH
(government) soldiers didn't put up much of a fight," one source said...."

"....However, the advance into the town was seen by intelligence assessors
as an opportunist move. "I don't think the Serbs had predicted the timing
of this operation," one source said. The apparent decision by the Muslims
to abandon the town provided the Serbs with a sudden opportunity to occupy
Srebrenica, bypassing the Dutch on the road a mile south of the town.

The intelligence source said: "The BiH just melted away from Srebrenica
and the senior officers left the night before." The source said the Muslim
defenders were "adequately armed" for street-fighting..."
Me: You are saying in that:
'To view the full analysis regarding the connection between Al-Qaeda and
terrorist activities in the Balkans, please visit the CPB Web site at:'
May you address me to the page where I could read it?

20.I2005. Sometimes I need youu to read this with me:
And those redish words, if you have a time.Thanks.
Believing in better future.

20.I2005. they got the money because they are racists?
Not very clear. Could you explain this to me, and why they got award for???

21.I2005. ** Message **
Is it because global warming, I wander?
** Jumbo squid wash up in California **
Hundreds of dead squid up to 1.8m long have washed up on beaches in California's Orange County, puzzling scientists.

21.I2005. Instead to send them somewhere, sad: ** Norway to kill 25% of its wolves **
A quarter of Norway's tiny population of wolves are to be shot to protect farm animals.

21.I2005. ** Dog gets German designer's house **
Murdered German fashion designer Rudolph Moshammer leaves his villa to his beloved pet dog.

22.I2005. Icelanders apologise for Irak war: but there is no democracy there is there?

22.I2005. ** Message **
So, between the lines, vegetarian food without using sweets and sugar in cooking is the best.Wow!
** Plant diets can ward off cancer **
Eating lots of fruit and vegetables and limited amounts of red meat and sugary foods is the way to protect against cancer, say researchers.

22.I2005. and human application? ** Alzheimer brain damage 'reversed' **
Scientists have reversed the damage caused to the brain by Alzheimer's disease during tests on mice.

22.I2005. ** Italy's real 'Romeo and Juliet' **
A man in Italy kills himself in despair over his comatose wife, hours before she regained consciousness.

22.I2005. ** How to make a greener computer **
Measures to make technology greener are long overdue says regular columnist Bill Thompson.

22.I2005. A parallel, analogy with Jews?

** Man found after weeks in cave **
A man is found alive weeks after getting lost inside a labyrinthine cave network in south-west France.

23.I2005. Congrats! ** India navy finds tsunami survivor **
An Indian man is rescued 25 days after being thrown by the tsunami on a remote island, the navy says.

23.I2005. Ivica Mladjenovicj: I have been searching for eco-sustainable gardening in fact, and I found this, I liked the sound and I wanted to contact the guy because I didn't get how many metres squared is apptmts surface per personand how big gardens are per person, and I realized when I have been slowly reading the end that he is Beogradjanin!!
I should call him, in fact, just to ask few questions. What a nice surprise...

17.I2005. Animal friendly Salty sea cosmetics: AHAVA, NATURAL SEA BEAUTY, MINERAL CARE, SPA COSMETICS, MALKI


23.I2005. Jews could have been saved/parallel with Serbs? : ** Why didn't the Allies bomb Auschwitz? **
One of the enduring controversies of the World War II is whether the Allies should have heeded calls to bomb Auschwitz when they learnt the full horror of the Nazi Holocaust.

23.I2005. Dutsch hospital people euthanasied 20 like these babies. What do you think?
I believe better would be experimenting them to the aim of survival.

23.I2005. Spina bifida baby retardation:

23.I2005. More on euthanazia /baby/ in Holland:

23.I2005. Robot soldier for Irak:

23.I2005 insulin receptors on cell membranes: google search

24.I2005. Holocaust industry /upsetting, but worth reading/:

when I planned to go to Israel, but did not get visa in May that year... personal but public for you to see, do not want to ask for viza again: 93 Mima,

Her: Pretty large field of interests - great!
I would recommend you to rent a car and to go to North Israel to visit Zfat - the town of cabbalists, then on Golan hights there is "Israeli Stonhenge" - very unusual place, very weird, and rarely visited-
Then there are great nature reserves as Achsiv and Banias, and if you go to South, visit the caves near the Dead Sea and Jericho site.
There is absolutely nothing to do in Tel-Aviv, so you can base in Haifa for North traveling or in Jerusalem for travelling in Central area (you can also see Herodion if you go with a guide - amazing place - )
Hope that was useful, and please ask me if you need any other details
93 93/93
93 Ksenia (or, it's Gzenia ;-))!
My fields of interest are Astrology, Kabala, probably Masonry and Templars
in this context as well as archeology and history (also nutrition and
vegetarianisme, physics, environmental studies and ecology, organic food,
animals, sustainable development (recycling, diminishing pollution...)
peace and prosperity on whole Earth, psychology, Perpetuum Mobile, life
extension, eradication of all diseases (i have a diabetes
insulinodependant), Yoga, sciences in general (apart from vivisection),
maths, music (I broadcast a commercial free chill-out internet radio
station)...). My partner is a Jew, so judaism as well and social impact
of all religions... Well I cannot remember more for now ;-).
Kind regards

11.XII2005. Novorapid contains aspart which is toxic when taken as sugar aspartame... I use it as insulin, it is only in NovoRapid. Together, all insulins have pesticide which is unnecessary, and I believe hydrochloric acid is unnecessary as well:
> NovoRapid® also contains the following inactive ingredients: glycerol,
> phenol, meta-cresol, zinc chloride, dibasic sodium phosphate dihydrate,
> sodium chloride, sodium hydroxide, hydrochloric acid and water for
> injections.
> Human insulin has the empirical formula C257H383N65O77S6 and a molecular
> weight of 5808.
> Human insulin (rys) is produced by recombinant DNA technology using
> Saccharomyces cerevisiae.
> One IU (International Unit) of human insulin corresponds to 0.035 mg of
> anhydrous human insulin
> (rys).
> Actrapid? (Neutral Insulin Injection) is a neutral solution of human
> insulin (rys). It appears
> colourless and clear. Also contains: glycerol, meta-cresol, zinc
> chloride, water for injections.
> Hydrochloric acid and sodium hydroxide are used to adjust the pH.
> Ultratard? (Insulin Zinc Suspension, crystalline) is a neutral
> suspension of crystalline human
> insulin (rys). When shaken gently it appears white and cloudy. Also
> contains: methyl
> hydroxybenzoate, sodium acetate, sodium chloride, zinc chloride, water
> for injections.
> Hydrochloric acid and sodium hydroxide are used to adjust the pH.

11.XII2004. Animal insulin and damned farmaceutical companies. Now, I excuse myself but could you culture S.Cerevisiaen to produce beef insulin for me, and Monotard in pure form like as it is from beef and without pesticides, please?
Read this. In fact, I do suffer from exhaustionm, had a seizure when hyppo and unexplained coma and feel bad and painful with all human and analog insulins I tried. Can you find out how much rapid and slow insulins cost in UK, both in pen, or just as an injection solution to suck in.

25.I2005. ** Climate crisis near 'in 10 years' **
The time for limiting greenhouse gas emissions to prevent runaway climate change is very short, a taskforce says.

25.I2005. ** Message **
if possible. 1.5bn$ for the embassy?
** Bush 'wants $80bn for war funds' **
The White House plans to ask for an extra $80bn, mainly for military operations in Iraq and Afghanistan.

25.I2005. /The borders of 1948 should in fact be promoted, but if it is from 1967, there is no way that they are extended without agreement from Palestinians/: ** Israeli barrier move sparks anger **
Israel resumes work on its controversial barrier, amid angry protests and criticism from Palestinian leaders.

26.I2005. Killer owls seen in Scotland:

27.I2005. /This is completelly alarming/: ** Alarm at new climate warning **
Global temperatures could rise by as much as 11 degrees Celsius, a major climate prediction project suggests.

27.I2005. No comment
** Kuwaiti 'slit daughter's throat' **
A Kuwaiti man reportedly confesses to killing his 14-year-old daughter because he believed she was having sex.

27.I2005. very disturbing, but true:

27.I2005. my correspodance with vegetarian croquettes for cats firm AMI: We thank you very much for your kind e-mail, and for choosing AMì products.

As per your questions:
1) yes, AMì cat food can be given also to kitties. We have several customers that feed their pet only with AMì pet food and they are all in perfect health. Of course, in case of different pathologies the veterinary advise should always be given.
2) all test refer from one to three years, as AMì does not effect lairaging.
3) there isn't a cholesterol value because it's a vegetable based pet food.
Regards AMÍ s.r.l.web site:
/I still wonder whether cat liver do produce enough cholesterol, please, check it out/.

27.I2005. ** Voters flock to blog awards site **
Voting is under way for the annual Bloggie awards which recognises the best web blogs of the year.

28.I2005. ** Message **
Indeed. If you are not sorry about animals, you should think about your health risk.
** 'Mad cow' disease found in goat **
European scientists confirm what is thought to be the first known case of "mad cow" disease in a goat.

28.I2005. Key to voluntary looking and refusing to look:

28.I2005. Viva la Sharon Stone! Apart that recently she wore animal fur jackets, I welcome this gest of hers:

29.I2005. Danger from ozone within weeks:

29.I2005. Aushwitz European press review:

30.I2005. Sabra and Shatila:

30.I2005 Bosna after the camps. ‘It's terrible that lessons were not learned from the Holocaust & that this happened in Europe within 50 years after the end of WW2.’:

30.I2005. Climate change disaster within two decades:

30.I2005. Interesting links /Something similar should be done for the sufferers of bombardments in recent years/:

31.I2005. Democratic society protecting the murderers?

1.II2005. Bosna’s muslim fate in Guant...
why muslims from abroad came to war in bosna, and who WAS for war and helping it at all...???

1.II2005. Coral reefs dissepearance in three decades as oceans become more acidic due to augmentation of CO2 in the atmosphere:

2.II2005. sunshine in fact food:

2.II2005. Birds’ abilities comparable to humans: That is why you should not eat them. They are having a 'chip' in the brain, that is why brain size is not so important.
Unfortunately, they are making now that mammals can perform less intelligent tasks than birds, mentioning rats. Rats are ultra intelligent, comparable to clever, wise and moral humans.Here is the link:

2.II2005. Nanotech chips in comps:

3.II2005. /There should not be sequestration at all, even in the used wells. We should just pass on solar and wave power and hydrogen batteries herein/: Sequestration of CO2 publicied as an option:
This just doesn't make sense??? To destroy already acidic oceans???

3.II2005. Climate conference grim conclusion:

4.II2005. Iran’s oilgas reserves: that is why USA wants to go in war

4.II2005. four percent of deaths related to alcohol consumption:

4.II2005. Havent seen:

6.2.2005. Activist goes to jail for the fight for clean air:

8.II2005. Link: Research has suggested that left-handed people are more susceptible to a range of problems, including allergies, auto-immune diseases, depression, drug abuse, epilepsy, schizophrenia and sleeping disorders.

13.II2005. How ecologic cars are not:

16.II2005. How the world is changing: To keep this link...

17.II2005. Hundred fifty thousand Serbs expelled for war for independence:

18.II2005. imprisoned without trial: ...politicians higher than judges??/

18.2.2005. greenhouse gases are warming the seas there is the proof, finally:

18.II2005 Time for studdying: For you too?

18.2.2005. individual medicaments from dna fingertip:

18.2.2005. sifilis for insects: feel nauseous

19.2.2005. thats why family members /animals/ are equally intelligent: brain size does not matter

19.2.2005. risky medicines approved by FDA:

19.II2005. lead and criminal:

19.2.2005. Indian wild tiger dissapear: On side of the article are lot of interesting links concerning environment and ecology.

21.2.2005. copyright copyfight bill thompson

22.2.2005. water formation in France:

22.II2005. parasit twin removed:

22.II2005 air pollution thickens blood:

22.II2005. energies renouvelables:

23.II2005. Party is over book : from OUSA env. forum student...

23.II2005. why there is not tax on airline fuel? from OUSA env. forum:

AS a veteran of the airline fuel business I have some info here for what it is worth. The reason for the lack of tax on airline fuel is complex in its simplicity. The problem is that airline fuel is consumed while the palne is flying over international airspace (except of course during take off and landing). As such it is being consumed in no one's tax jurisdiction. If you were to tax it who would receive the revenue on say a London New York flight? In the same way that if you buy goods in London as a US tourist, you can claim back the VAT when you leave the country. The same principle applies for airline fuel.
Now one could have an EU tax covering flights within the EU, but this would be a first case of the EU being a direct tax revenue raiser, rather than the individual countries raising taxes and then paying dues to the EU. If I understand correctly the EU has no mandate to raise taxes.
This subject goes on and on so I will quit here, but also bear in mind that some countries would then compete with low taxes to attract airline hubs. Once again an easy solution turns out to be not so easy.

24.II2005. SUPERB! Ban on plastic bags in Kenya: thousand year to decompose... Could you diminish their use, please???

3.III2005. It seems it needs to be local organic food:
environmental costs, transport, savings... Local food greener than organic title

3.III2005. Can planet feed us? The answer is more political than economical.

3.III2005.These mushrooms are legal in some countries:

3.III2005. What a democracy for twenty first century:

3.III2005. Biodefence in USA, this is upsetting:

4.III2005. Quote: I think that religion and school should be separate full stop. Choosing the path of blind belief rather than of scientific thought is a very big decision and should not be made until adulthood.
Andy, Stafford, UK

4.III2005. Opinions about Muslim dress code in Britain:

5.III2005. Three strikes laz for repeated offenders:
This is not normal at all.

5.III 2005. Bonjour au groupe AT-Transports,
Ci-dessous quelques "exemples venus d'ailleurs" pour diminuer la pollution générée par les transports, glanés lors d'un cours sur les transports pendant ma formation.
Je m'excuse de n'avoir pas le temps de les développer, cherche un emploi en ce moment (tout en finissant ma formation en "management urbain & de l'environnement") et c'est ma priorité.
Mais peut-être cela peut-il esquisser quelques pistes pour la partie "prospective" de l'exposé ?
A la prochaine séance peut-être, bon courage pour la rédaction.
Emilie ("nouvelle" ou plutôt "revenante" des AT).
Singapour : des efforts considérables pour instaurer un péage urbain
et diminuer la circulation des voitures en ville. Problème : ségrégation par le $.
Allemagne : taxe pour les camions (source : magazine Silence de mars 2005) :
depuis le début de l’année 2005, les poids lourds doivent payer
12,4 centimes d’euro du kilomètre pour emprunter les autoroutes allemandes.
Hambourg : des locations de voiture sur des distances courtes (mode de transport banalisé).
Californie : gestion souple des infrastructures routières (voies à sens unique, certains sens de circulation bloqués…)
Danemark : des strapontins à vélo le long des fenêtres dans les wagons de train
Dublin : les étudiants transportent les citadins dans des pousse-pousses à pédales (sortes de "tuk-tuks") : un job étudiant...qui muscle les mollets. Source : ma soeur, habitante de Dublin.
Suisse : des transports scolaires très organisés (évite les congestions urbaines
causées par les trajets domicile-école en voiture des parents)
Reconquête des centres anciens piétonisés : Bologne, Florence, Padoue.
Amis de la Terre

6.3.2005. Still slavery exist :

6.III2005. Aborigines from Nicobars face extinction. this is turning my diaphragm upside down. They ought to be saved.

6.III2005. mp’s flights pay higher prices to curb pollution:

6.III2005. Havent listened:

7/3/2005. Dermatologically classified children to go in separate schools in UK?

7.III2005. Again demonising Serbs: 'Serbs know where mladic is' implies 10million people know where the man is. What a demonisation.

7.III2005. Complaint to BBC for demonising Serbs: 'In another development, the court's chief prosecutor said Serbia knew where top suspect Ratko Mladic was hiding.', from the article 'Serb general surrenders to Hague' is a problem.

May you stop demonising Serbs because by this remark you imply that 8 million people know where one person which more than 50% of Serbs anyway want to see in court is hiding. You may say Derbian police or whatever else, but, please, please stop demonising my family, friends and the rest who DO NOT HAVE IDEA where gen. Mladic is.
PS. Will you correct the blame you caused to my family or I shall complain to other sources?
Thanks in advance. Sincerely,

7.III2005. Eat what you want pill for diabetes: is not great

7.III2005. Polica raid over home alone hamster: He needs daily maintenance and cuddling, though.

Poem for our late pets /members of family that need to be cloned/: at the rainbow bridge

8.III2005. In your own time: All the pages from this site are for reading. This page is a must...In your own time, when you can, could you please take a look?

8.3.2005. Diabetes type three:

9.3.2005. lucrative sf book awards: i hope we will get it with our book onne day... 100000 euros.

9.3.2005. Danger of supervolcanoes: PS. If this happen and I survive the volcan erruption, I would die without insulin.

9.3.2005. Israel funded illegal posts. Who exactly?

10.3.2005. Dear Pacho: donkey...

10/3/2005. Now about someone else:
dog witness on trial

10.3.2005. Laughter boostes health:
cortisol levels are smaller when happy /me/.

10.III2005 house music and the rest:

10.III2005 Paris clubbing:
12.3.2005. billionaires rich list, you may find new stock to invest in here:

Moje pismo drugarici, 12/3/05, delim ga sa vama premda nisam sa istim likom:
Ja sam prvo ovo poslala na forumu, al pomislih mozda je prejako za ljude pa sam izbrisala. U svakom slucaju tebe vec smatram za drugarsku dusu pa evo ti, citaj:

Kad sam ja predlagala mom dijabetologu da idem na pumpu on nije bio za to jer se plasio da nema nikog da me nocu proveri i da mogu da padnem u komu. Ja sam tada zivela sama, pardon, sa mojim pacovima (nemoj se mrstiti oni su divne, inteligentne, socijalne i jako ciste zivotinje). Davala sam sebi 3-4 puta dnevno NPH (ili Insulatard) zajedno sa Novorapidom svaki put kad je potrebno. 3-4 puta dnevno NPH zato sto ja jako brzo absorbiram insulin te traje krace. Cak i lantus meni traje oko 8 sati pa onda preko celog dana moram da dajem male inekcijice kad god je potrebno, pored onih obaveznih pred jelo.

Elem, ja sam tada cesto padala u hipo i dr. se bojao. 3 puta su me moji pacovi probudili iz literalne kome (hvala im zauvek sto su mi spasili zivot) tako sto su me satima lickali i grickali po licu. Ja bih osetila da su na mom licu, pretpostavljam odgurnula bi ih, oni bi se vratili i pretrcavali preko lica i ponovo mi lizali oci i grickali me. To je trajalo vecnost, oni su bili uporni, na kraju sam shvatila da sam u uzasnom manjku ali bih se ponovo kontuzovala, oni bi opet nastavili, pretrcavali, grickali, zuborili u uho (sto inace ne bi radili kad spavam, uglavnom bi se scucurili pored mene i spavali i oni)... To se ponavljalo, ja bih samo shvatila da mi treba secera i onesvestila se, oni bi opet Jovo nanovo. Na kraju sam htela da ustanem i uzmem secer ali sipak! Ne samo ogromna glavobolja i skroz mokra i ja i posteljina nego sam bila paralisana. Vrtela se levo-desno, opet spavala, oni me budili, onda spala sa kreveta. Boze kako je to bilo strasno, puzala sam minutima, noge nisu htele da slusaju, ruke i one nisu imale snage i pravile bi tikove. Ja bih zaspala ali bi oni trcali ispred mene, ja sam tada napokon shvatila da sam u stvarno losem stanju i da mi nece pomoci da spavam na podu da moram da uzmem secer... ali to puzanje, to neslusanje misica, to kucanje srca...

Na kraju sam otvorila kutiju secera u kocki, pojela pola kilograma (literalno) i posle jedno 20minuta pola sata proverila secer 19mg/dl(0,95mmol/l), i to posle secera!!! Nazvala partnera, ali i to je bilo skoro komicno, nisam mogla da potrefim brojeve, ruka nije htela da slusa, nanovo i nanovo dok ga nisam dobila da mu kazem da sam, eto ziva uz pomoc mojih pacovcica. Nisam mogla da govorim, mucala sam (to je bilo skoro sat vremena posle jedenja secera), jos uvek sam bila paralisana, koliko sam se uplasila tada da sam gotova i da se necu izvuci. Ovi su bili pored mene i gotovo groktali (inace su oni jako tihi i nisu oni morski prasici da grokcu), i znala sam da su srecni i da me i dalje podrzavaju ...

E, pa pored tog jednog puta, bila su i druga dva kad sam bila polu svesna i mnogo puta kad bih bila samo u manjku kad bi me probudili...

Zadnji iz te moje pacovske porodice je umro u junu 2004. Ja sam od pocetka februara pocela da zivim sa mojim partnerom i Sanijem, zadnjim pacovom. Morala sam da obecam da ce mi to biti zadnji jer je darlin' imao jaku alergiju i morao je prvi dan kad smo se uselili da dobije steroidnu inekciju, a zatim je svaki dan uzimao antihistaminske tablete. Ali kad god bi poceo da se mazi sa Sanijem jer ga je obozava dobio bi crvene pecate po ruci i oci bi pocele da ga svrbe i poceo bi da smrkce i da ga steze u plucima...

Ja sam kad je Sani umro sacuvala par njegovih dlaka kao i ostalih 6 kojih sam imala da mogu jednog dana, kad pronadjemo lekove za bolesti i imamo mogucnost da neograniceno produzimo zivot da, ako ja budem tada ziva da mogu da ih kloniram i vodim racuna o njima.

Nego da se vratim na tvoje pitanje. Posto sam imala Sanija a i posto je moj covek shvatio da sam ja nemoguca da delimo krevet (ritam se ko konj i kradem jorgan i prevrcem ko na takmicenju, a neki put i mrmljam) ja imam moju sobu gde spavam a on njegovu. E, sad, sta ako opet upadnem u takav manjak, toga se plasim... Mada od kada sam na lantusu mnogo je stabilniji nocu secer pa nisam toliko zabrinuta...

Ako se desi da zatrudnim, verovatno cu staviti pumpu ako je to najbolji nacin kontrole. Verovatno cemo morati da napravimo razmestaj u njegovoj sobi i da kupimo dzinovski krevet takon da ja mogu da se ritam i prevrcem koliko hocu i imam svoje cebe al da je on tu da moze da me cekira, oseti ako sam se preznojila.

Ispricala sam ono o pacovima zato sto sam htela da razbijem nekim ljudima predrasude o tim divnim zivotinjama. Da, od kad sam njih imala sam postala vegetarijanac i nisam za experimentisanje na zivotinjama, oni su nasi prijatelji i pomognu kad imaju mogucnost, zato nisam za njihovu patnju pogotovo kad postoje jeftiniji, brzi i viabliji za ljude metodi koji su eticki u svakom smislu. Mislim nemam ja nista protiv da ljudi koji vec imaju bolesnog ljubimca kazu OK za experimentalni lek da se proba, i to je OK, ne da ih pare da ih drze u kavezu bez da ih pomaze celog zivota i bez da im daju da se istrce po prostoriji i onda, uuuh, verovatno i ne znate sta se sve radi sa tim dragim, inteligentnim bicima...I zbog svog genetskog tipa, i zbog same odvojenosti vrsta (jedna vrsta se ne moze reprodukovati sa drugom), isti lekovi drugacije uticu najednu i drugacije na drugu vrstu...

Samo da dodam, znate li da je Sani voleo da golica svoju tetka Minu i ona bi se smejala visokim skviksima? I naucnici su dokazali da se pacovi smeju, posle sam saznala (za takve vrste naucnih observacija nemam nista protiv). Ja sam i za logo na mom sajtu stavila crtez pacova, mozete videti na mimaradio tacka com.

Od kad sam vegetarijanac holesterol mi je odlican, samo da dodam.

12.III2005 Bail for detainees is not fair play : not to go to prison

13.III2005. Jordan river and the Salty sea: Jordan river will run dry in two years. Dead sea shrunk 30% in last 50 years. Lots of blame on Israel.

13.III2005. France prepares to vote for EU Constitution:

13.3.2005. worth reading:
Chrissie (east enders) is a Jew. I didn't know.

14.3.2005. Himalayan glaciers melting fast: and world temperature may rise as much as 2 degres within TWO decades.

16.III2005. read when you have time, but worth reading: It's about smoking but sincerely worth reading -it will take few good minutes, though .

17.3.2005. world bank nomination:

18.III2005. trees plantation:

18.III2005. 1500-3825 trees/ha

19.III2005. Cows enjoy solving problems: How you could it them and others, then?
Farm animals are sentient beings, the study proves.

20.III2005. French:

20.III2005. DigiBio Research Laboratory:

21.3.2005. Cosmetics hot list:

21.III2005. may be animal derived:

21.III2005. taken from OU:
Nuclear or Not? An overview by Dave Elliott

With the likely social and economic costs of climate change being taken increasingly seriously, the nuclear lobby is arguing that it has at least part of the answer since, unlike coal or gas fired power plants, nuclear plants do not generate carbon dioxide gas, the main greenhouse gas responsible for climate change.
Nuclear power had fallen from favour due to the high costs, and concerns about plant safety and radioactive waste disposal (1). More recently security issues have come to the fore. However, if we have to phase out our use of fossil fuels to reduce the impact on the climate system, then, say the nuclear proponents, what other energy source is there? The renewable energy lobby argues that it has the answer- there are many new green energy sources which can provide all the energy we need without any emissions, and they are developing rapidly, especially in countries which have decided to back off from nuclear power (2). In addition, we can avoid wasting so much energy- so that it becomes easier to meet our needs from renewables sources.
The debate between these two positions sometimes focuses on the problems each perceives with what the other side are offering, in terms for example of direct costs. The reality seems to be that there is not much in it- nuclear power is currently expensive, but so is wind power, although both could get cheaper (3). There are also technical arguments. Nuclear plants only produce electricity, whereas that’s is only about 30% of what we need; renewables can provide heat and transport fuels, as well as electricity (4). However, the counter argument is that some renewable energy sources are intermittent and are not reliable as electricity sources, and growing biofuels for vehicles would take up a lot of land space (5). Plenty of rooms for debate there.
The comparison gets more favourable to renewables when we look at some of the other major differences between these two types of technology. Nuclear plants need uranium to fuel them and inevitably produce dangerous long-lived wastes, whereas most renewables need no ‘fuel’ and produce no wastes, and so there are no fuel or ‘backend’ costs. Moreover, when nuclear plants come to the end of their working life they must be decommissioned, which is a very expensive process- which generates yet more wastes. Nuclear facilities are also potential terrorist targets, whereas most renewables are unlikely to attract the attention of terrorists (6).
It is not surprising then that most people oppose nuclear power- opinion polls have over the years have typically indicated that 70-80% of those asked were against an expanded nuclear programme, while about the same number were in favour of renewables like wind power- although opposition to wind projects generates a lot of media coverage, it is very much a minority issue (7).
However, things may be changing. The nuclear lobby says that actually, in the UK, opposition to a ‘replacement’ nuclear programme (replacing the UK’s old plants as they are retired), has fallen in recent years, no doubt reflecting growing concerns about climate change (8). The renewables lobby replies, if climate change is so important then that is all the more reason to expand support for renewables, since they are the best bet for a long term sustainable energy future. Going back to nuclear power would simply divert resources from developing renewables. Moreover, why try to solve one environmental problem (climate change) by creating another (radioactive pollution), especially since long term we will have to switch over the renewables, since there are only limited amounts of uranium available in the world? (9)
So the debate goes on. On one side we have renewable protagonists arguing that renewables could supply 50% of total world energy requirements by 2050, compared to the 7% currently supplied by nuclear power. On the other, some nuclear proponents say that new nuclear technologies will be cheaper, cleaner and safer, and that in any case, the costs and risks of climate change outweigh the problems of nuclear power. Some say- why not have both? But we don’t have the resources to do this, and in any case we then risk doing neither well. We really ought to decide which to back. Nuclear power has had the lion’s share of funding for many decades, while renewables have been starved of funding (10). Perhaps it is now time to give renewables a chance to show what they can do? (11)

(1) No new nuclear plants have been ordered in the USA since the Three Mile Island accident in 1979 and following the Chernobyl accident in 1986, most of the EU decided to phase out nuclear power. Globally over 30 gigawatts of nuclear plant has been closed or retired, although China and India are still expanding their nuclear programmes
(2) Denmark gets over 20% of its annual electricity requirements &om wind turbines. Germany has installed over 16 gigawatts of wind generation capacity. So far there is around 42 gigawatts of wind capacity in use in the world and around 70 GW (thermal) of solar energy conversion capacity.
(3) The 2002 Cabinet Office ‘Energy Review’ estimated that by 2020 on shore wind would the cheapest energy option at 1-5-2.5 pence per kilowatt hour (the current average price is around 3p/kWh), while offshore wind farms might generate power at between 2-3p/kWh. It suggested that new nuclear plants might generate at between 3-5 p/kWh, but the nuclear industry claims that it can get it down to 2.5p/kWh.
(4) Electricity from nuclear plants could be used for electric vehicles and also for producing hydrogen gas to power vehicles, But that is also true of electricity from renewables. In theory, waste heat from nuclear plants could be used in district heating networks, but that would imply that the nuclear plants had to be in or near inner city areas, and so far all the UK’s nuclear plants have been put in remote areas on safety grounds, usually by the coast to get access to cooling water. That actually may prove to be a problem in future, given the risk of sea level rises as a result of climate change. However, locating nuclear plants in-land may also be a problem since water is likely to become an increasingly scarce resource due the climate change. That of course could also effect the viability of biofuel and energy-crop production.
(5) The intermittency of some renewable sources like wind is not a major problem. The existing power system already has to cope with sudden large variations in power supply inputs when conventional power stations unexpectedly go off-line. As long as the total contribution from intermittent sources is less than about 20%, the smaller variations in input from these sources is in effect balanced out by the national grid system. Above a 20% contribution then we may need more backup plants and energy storage systems, but by that time we could be using renewables to generate hydrogen gas, as a new energy medium, and that is storable.
(6) Over the next century the UK will have to deal with 500,000 tonnes of nuclear waste of various types as existing plants are closed and decommissioned. The total nuclear liability has been put at 548billion. BNFL currently spends f.50m pa on security e.g. armed police to protect against terrorists
(7) An opinion Poll for the Royal Society for the Protection of Birds found that only 3% of their sample opposed wind farms. In the 'worst case' poll, in Wales, objectors were14%.
(8) A Mori poll in 2001 found that 19% favoured a replacement programme, while 57% opposed it. By 2004 the figures had changed to 30% for and 34% against.
(9) Reserves depend on the price that is acceptable and the rate of use. In 1990 the UK Atomic Energy Authority said that, using conventional thermal/ burner reactors, ‘ for a nuclear programme that expands continuously to about 50% of [electricity] demand, uranium resources are only adequate for about 45years’. Uranium finds since then may have increased the resource, but a major nuclear programme would lead to lower grade ores being used, which would require more energy for fuel production and lead to more carbon dioxide emissions,
(10) UK Government funding for nuclear research and development ran at around f.200m through most of the 1970’s, whereas spending on RED for renewables only rose gradually to about 10% of that before being cut back under the Thatcher government. Renewables still only get around K20m p.a. for RScD, while nuclear power gets around 560m p.a. (excluding the liabilities). However, a new renewables grant scheme is now offering more to help new projects get going, including grants for offshore wind, wave and tidal current projects.
(11) The government’s 2004 White paper on energy saw renewables and energy efficiency as the main way ahead but said that nuclear power should be kept open as an option for the longer term in case renewables and efficiency did not deliver as hoped. More recently interest has also been shown in undersea carbon sequestration (storage in old oil and gas wells) as a way to allow us to continue to use fossil fuels for a while, without having an impact on the climate.
Prof. David Elliott, EERU, Open University March 2005

22.III2005. Toxic ingredients in cosmetics:

22.III2005. Theology: of thelema
Please read, indeed I do agree with most of things except for putting the main concepts of Winged Serpent to be Hadit and Horus as hawk headed deity. I would put those main deities to be human-like, or allegoricaly like some other indeed holy concepts, as both serpent and hawk are rodent eaters and they are not able to control such hunger until, one day, we, humans do not teach them otherwise (in beggining giving them veggy food and afterwards bring them to evolve into herbivores).
But most of the other theology concepts are quite good.

22.III2005. UK’s carbone dioxide /CO2/ emissions: In fact, EVERY UK citizen makes over a TONNE of carbon emissions per year!!! This is ultra dangerous.

22.III2005. Traffic fumes damage human DNA:

24.III2005. ‘Occupation of Irak till at least 2006’: who will continue to pumpo oil from there after, i wonder?

24.III2005. Builders threaten Panama forest:

25.III2005. I found this veggy shoes in France:
Ecolution: everything here

25.III2005. Vegdinning: also search for happycow its worldwide

25.III2005. nerve signal:

26.III2005. PV Britain roofs, quote:
How much can photovoltaics really produce in Britain? The DTI have estimated that solar panels installed on buildings have the potential to provide all the electricity that Britain currently uses, however that would mean photovoltaics on most south facing roofs which is unlikely in the near future. However, an ambitious solar roof programme coupled with other renewables such as wind and wave power could play a significant part in the move toward a sustainable future. How environmentally friendly are photovoltaics? The manufacture of photovoltaics involves the use of toxic materials to obtain the necessary standards of purity which are vital to performance. It lies with the manufacturer to ensure that dangerous substances are dealt with and handled correctly. Over its estimate

26.III2005. UK media biased over Israel:

26.III2005. Historic homeland : Address by Prime Minister Netanyahu to the United Nations
General Assembly, September 24, 1998, Ministry of Foreign Affairs;

26.III2005. One day, whether rich or not I want to be minder of these threatened species: like those beautiful people in New Zealand are.

27.3.2005. parrokets /papagaji/:

27.III2005. Mithohondrial mutation in centenaries: old age link to mith mutation
Published online before print January 21, 2003, 10.1073/pnas.242719399
PNAS | February 4, 2003 | vol. 100 | no. 3 | 1116-1121

27.III2005. blog :

27.III2005 Energy efficiency of cars and other:

27.III2005. Boron fuel of future /with robotised mines only/: does it have toxicity?

27.III2005. Technology, energy, transportation:

27.III2005. Indirail: safe?

28.III2005. Lepa is there:

28.III2005. Fantastic move from Mairie de Paris:

29.III2005. here it is, hair contain stem cells: so in theory cloning from hair cells seems likely. Even earlier, the cures of diseases by using adult stem cells from hair is hear. They suceeded to convert them into nerve cells already.

29.III2005. Cat allergy can be blocked: so rat allergy will be possible to blocked as well

29.3.2005. A point of view, science and religion:

29.III2005. Tesla’s automobile:

29.III2005. Precious, need more of them : Tesla’s patents :

29.III2005. Tesla and others patents : tesla and others

29.III2005. Free energy: and some patents and links

30.III2005. Ecosystems world survey:

30.III2005. quote: Hear hear on both counts. The Millennium Ecosystem Assessment was released today, showing that the human race better wise up, and quick;,12996,1447921,00.html

30.3.2005. Feljtoni o Tesli, needs translation:

30.III2005. U secjanje na dzhina, needs translation:

31.3.2005. Mad plan for energy, quote: In the US they must be getting desperate - this seems like a mad energy plan to me;
“Lunar solar power bases will be built on the Moon…”

31.3.2005. Earth magnetic field reversal:

31.3.2005. pure energy systems: renewables, free energy, tesla, updates...

31.III2005. AAH /allocation adulte handicape/

1.IV2005. Paralized man controls stuff by chip in the brain: When main researcher says 'the work is very exciting' it realy diminishes the meaning of his work. Exciting is not the right word at all, he is a medic, not a child and he should behave like as if he has phd.
By the way, i know that Stephen Hawking, a physicist, talks through machine which picks up his brain thoughts for years already. How this can be the first person, then?
Dont be late, BBC, mind my anger.

1.IV2005. DNA fingertipping babies rejected, why?

15.IV 2005. EU pollution deaths cost billions:

1.IV2005. pills thyroxine could prolong lifes: by 30%, maybe. I hope they will be made in Bioprogress' pills.

2.IV2005. hemp paper:

2.IV2005. Animal laugh:

2.IV2005. contre REACH:

2.4.2005. toxic for humans, not animals:

2.IV2005. global warming grim news:

2.4.2005. hockey stick –global warming temperature rise:

2.IV2005. periferal nervous system:

2.IV2005. salon du livre greenpeace plume verte:

3.IV2005. millenium ecosystem assesment : OU T206, tgv, air, travel energy pollution:

3.IV2005. Turkey, EU, penal code :

3.IV2005. Israelis to leave Gaza homes intact /or better to destroy but they exarcebate the price/ :
Considering just 3 people per house, 3000 american dollars is too expencive for destroying one house in my opinion. Bombs and granades not more than 200-300, making it to rubble 100, picking up with buldozer and travelling to recycle it on another place 200 maximum. 100 to all people involved that is maximum of 700 american dollars, not 3000. Plus, there is more than 3 people per house (see the house sizes on picture and natality of Israelis) so it should be even less houses.

3.IV2005. Click on line – blogging:

3.IV2005. e-waste recycling law in 2006?

4.4.2005. Answer: Joint combined exchange training: "Joint combined exchange training is a regular programme that special operations command Europe conducts throughout many countries in our area of responsibility."
This means that some outposts of the US military in europe do special joint operations together with their equivalent sections in other european nations. Me: On Sun, 03 Apr 2005...which is our area of responsibility' above Albania is responsibility area of USA?

5.IV2005. diabetes two prevention:

5.IV2005. Bionic eye from next year on humans: Let all people may see the world I got the chance to see again!

5.IV2005. Roma in Srbija /just see his articles alltogether.../

6.IV2005. Alkohol bad for breastfeeding:

8.IV2005. Shta cje joj?

8.IV2005. Cure for cancer in five years:

9.4.2005. Pleasure to read this:

10.IV2005. (from Vivien, a vegan from OU forum). Does this have any connection with REACH?
At the link below you will find an article subtitled "Human Toxicity Data Is Exactly What the Enviros Don't Want."
It is full of barefaced lies, including claims that
"The environmentalists' real gripe is somewhat less likely to be articulated in the media: these groups have fought against using human toxicity data tooth and nail because they know quite well that such data will show no evidence of harm to humans from the so-called "toxins" in our environment."
In fact there has been ample evidence for decades about the harmful effects of commonly-used chemicals on humans. For examples see:
and I have come across more via the fpin website
although the links from the latter don't work - I had to cut and paste the article titles into Google to search for them.
The website for the dishonest article is run by the AMERICAN COUNCIL ON SCIENCE AND HEALTH (ACSH). I could not quickly find details on how the organisation is funded, so did a Google search and found this:
I was not surprised to find that ACSH is funded by all the usual suspects (Monsanto, etc.).

Many thanks to Medialerts for alerting me to the article.Vivien
Graduated 2001 BSc (Hons) (2.1) & DipNatSci
Graduated 2004 MSc (distinction) based on 'Frontiers in Medical Science' strand
"One might expect that these animals (bred to have human cancer genes) would mimic human symptoms, not just the genetic mutations. In fact, that is usually the exception, not the rule." T. Jacks, Science, 7th November 1997, vol. 278 p. 1041

11.IV2005. Primates, quote :
One quarter of 625 species of primates will dissapear within 20 years from human activities (poaching and loss of habitat).
If we put all the primates (except the humans) on the seat each, they will be no more of them than the public seats of ONE FOOTBALL STADIUM.

12.IV 2005. Nanotechnology:
1) Energy storage, production and conversion
2) Agricultural productivity enhancement
3) Water treatment and remediation
4) Disease diagnosis and screening
5) Drug delivery systems
6) Food processing and storage
7) Air pollution and remediation
8) Construction
9) Health monitoring
10) Vector and pest detection and control
2) and 10) are dangerous. 5) and 6) cannot be controled once released in the body. Here belongs and 3).
7) and 8) may not be able to be controled in the environment, after they finished the job...Should find out more, though.
1), 4), 9) am looking forward to see the development.

12.4.2005. Israeli prime minister wants to expand settlements: Sick.

12.IV2005. electrotechnique:

14.IV2005. Made in US of America :
They should have given them narcotics..

15.4.2005. nerve regeneration: spine regenerated in paralized dogs.
few years until tried in humans? so long? scientoist need to earn money?

15.IV2005. oil for food UKGBNI and USA's, not UN mistake.

15.IV2005. nerves nose regeneration

15.IV2005. credit to OU students for this: 1/3 UK's food gets trown:
Around one third of food grown for human consumption in the UK ends up in the rubbish bin, new figures reveal.
BBC rural affairs correspondent Tom Heap said demands for "pristine looking" produce means a lot of food does not make the grade and never leaves the farm gate.
People are eating out more and the catering industry throws away one third of all they buy, he said.
A lack of time or knowledge to use up leftovers is also to blame for increasing food wastage.
In the UK, a shocking 30-40% of all food is never eaten. In the last decade the amount we binned went up by 15%. Every year each of us throws away over £400 worth of food - that's £20 billion pounds overall, enough to cover the cost of everyone's council tax.
And it's not just the financial loss. The environment suffers too. Food grown but not eaten means more farm chemicals; transported and not eaten means more food miles; processed and thrown away means more rotting food churning out methane - the most potent greenhouse gas.
Every indication is that with the continuing trend to eat out more and the rise of convenience food, the figures will only increase as they have on the other side of the Atlantic. A 10 year study by Tim Jones at the University of Arizona has shown that 40-50% of all food in the US ready for harvest never gets eaten.

16.IV2005. UN and question:
These are some comments. What do you think? Please answer.
(This is the original BBC article after which people gave their opinions. )

16.IV2005. Chimpanzey told to stop smoking:

16.IV2005. 100 year old takes IT course: Lots of exercise, oats in morning...

Oats recommended instead of bread /me/

17.4.2005. Biochip: Big as a human hair, could give all results from a drop of blood. More, it should test drugs from human cell, so no animal experimentation in sight?

17.IV2005. rent a car -environmentaly friendly. Did i understand good that that is an electric car?
30 millions cars in China. Expected 130 millions within 5 years... We will such zipcars as the crude oil reserves will not last 20 years, and because of geohazard prevention we need to stop pumping out oil soon. Answer: i saw no mention that the cars are electric but no reason why they cant be in future I guess. It is still eco-friendly as they think every car they have in this scheme means 20 people no longer require to own a car.

17.4.2005. gym, plastic surgery, face lift, celebrities in 40’s.

17.IV2005. Badmington and other activities in 18th arrondissement in Paris:

18.IV2005. vegan barbeque

18.IV 2005. Aspartic acid, connection with neurodegenerative diseases and aspartame sugar as well:

18.IV2005. Parkinson disease and aspartic acid, aspartame digestively influences vagus nerve, through muscle in insulin Novorapid what influences?

18.4.2005. Believe that for eternal life food without alkaloids as first derivation of perpetuum mobile we are is necessary, that is why humans stil consume meat and carnivores like cats can give birth to kittens all their life, no menopause. Alkaloids even in small quantities even though have medical properties have poisonous effect, exception I wander for the cocaine and another if alkaloid because mushroom is LSD iz razhi. Alkaloids from fungi different studying zasluzhuju. Alkaloids: Maybe some people need certain alkaloids chronically, but not cofee and tobacco, instead is better to plant cocain, not diamorphine’s opium as even not good as pain reliever, again better to plant cocaine. Not teas and not curry, chilli perhaps.

18.IV2005. STill first: What a woman!

19.IV2005. sf female competition:

20.IV2005. Natrium, diabetes, hypertension quote:
B. Excess of dietary sodium is associated with an increased incidence of arterial HT, whereas populations that take less than 30 mEq/day of sodium exhibit virtually no HT, and no rise in BP with aging. Many investigators noted a positive correlation between dietary sodium intake and BP levels in diabetic patients. Numerous studies have shown that exchangeable sodium is increased by approximately 10% in diabetic patients. The increase in exchangeable sodium shows a positive correlation with age and systolic BP. It has been suggested that increasing Na reabsorption is associated with hyperinsulinemia. This leads to an increase in intracellular sodium and calcium concentration and rise in peripheral vascular resistance. Moreover, insulin activates the sympathetic nervous system, which leads to sodium retention and elevation of BP However, due to salt sensitivity, high dietary sodium intake is a does not always cause significant BP increase. One of the reasons congenital reduction in the number of nephrons leading to a diminished capacity to excrete a normal sodium load. Nevertheless, salt sensitivity can be caused by insulin resistance, increased sympathetic activity, decreased products of prostaglandin, and endothelial defense. Salt sensitivity is associated with LVH, microalbuminuria, and CV mortality (Figure 2)

21.IV2005. amateur inventor worker makes antithrombosis: how workers can diversify from ecologicaly unsustainable job,8363,1464080,00.html

23.IV2005. Hypertension:

24.IV2005. Ants maybe the most evolved animals after rats and humans?
It reminds me on human history brutalities and sacrifices...

24.IV2005. Cats: better for indoors if you are a real animal lover.

25.IV2005. iron oxides toxicity:
found in powder

25.4.2005. here it is- unconscious thoughts detected: may be route to time machine

25.IV2005. gene therapy success in threating Alzheimer’s disease:
But, you see, after animal experimentation they did this therapy under local anestezija and 1 patient died because of false results.
nerve cell regeneration from adult skin cells...

25.IV2005. 16000 Priceless items stolen from Irak museum:

26.IV2005. Astrologie:

26.IV2005. Parisian kiss lovers poster fetch 150000 euros:

26.IV2005. Brain stem cells to cure diabetes:

26. IV2005. ..reuptake transporters
AIE amis de la terre

26.IV2005. Vermiculture : composting sewage earth worms make first class organik land

27.IV2005. British prime minister was advised Irak war could be illegal: please, explain the last two paragraphs to me, please.

27.IV2005. Nuclear dump waste in Macedonia:
'Nato already have used few other sites of Macedonia to dumps nuclear waste...'

28.IV2005. free neutrons and fission:

29.IV2005. Obesity increases dementia risk /too much food for brain, brains food is glucose and oxygen/:

29.IV2005. frogs saved from blender by ecological police:

30.IV2005. Quantum security control: who owns it? So, ToShiba has a patent? Answer: I think so but it depends on the agreement between toshiba and the company developing the technology. For example it is possible that toshiba may have the rights as sole worldwide distributor for x number of years in return for funding the development of the technology but the inventor still retains the patent.

30.4.2005. NIVO comps: Which means, when people switch to them (just 5 W whilst PC 100W), repair comps firms will loose clients. Does it autorepair itself or its online for free? Where and who is 'brain' computer?

30.IV2005. acidity carbon dioxide oceans: in search bbc

30.IV2005. TV:

1.V2005. genetic sequencing could transform medicine:

2.V2005. Nuclear weapons desarmement:

2.V2005. Bill Thompson:

2.V2005. Agent orange Vietnam /to clean/ :

2.V2005. Slovakia:

2.V2005. CO2 sequestration:
Microbiological impacts of direct carbon dioxide injection - Exploratory studies under deep-sea conditions
Douglas C. Nelson, University of California, Davis
Among strategies being considered for combating an increase in atmospheric CO2, is injection of this greenhouse gas into the deep-sea. Based on the formation of solid hydrates at sufficient pressure, discharge at a depth of approximately 3000 m at sites near the sea floor seems most likely. The biological consequences of the resultant local increase in CO2 concentration and decrease in pH (= increase in acidity) are difficult to predict. Nonetheless, the narrow range of natural pH variability found at this depth suggests that both microbes and animals evolved for optimum performance there might be sensitive to CO2-induced acidification. If a pH decrease near the point of injection is as much as a whole unit, localized die-offs of deep-sea animals are possible, which -- based on the activities of diverse microbes -- would result in increased local production of organic carbon compounds, ammonia, hydrogen sulfide and nitrate. The injected CO2 stream is likely to be contaminated with other industrial gasses such as H2, CO, and SO2, which adds to the microbial transformations that must be considered. Microorganisms in the deep-sea uniquely perform several of the fundamental transformations that allow global cycles of nitrogen, carbon and sulfur to be sustained. In its essence the research in this proposal begins to test whether deep-sea injection of CO2 and resultant acidification might adversely impact the global cycle of certain major biological elements. The processes to be tested at in situ and more acidic conditions include:
1. Respiration of organic matter in the presence of oxygen. Typically, this would occur in the water column.
2. Fermentation or respiration of organic matter in the absence of oxygen. Typically this would occur in marine sediments and might also involve the reduction of nitrogen- or sulfur-compounds.
3. Oxidation of reduced inorganic compounds, e.g. ammonia, hydrogen sulfide, molecular hydrogen or carbon monoxide. These compounds will either be co-injected with CO2 or arise from sediment microbial processes discussed in point (2).
Initial studies will be undertaken with samples of natural seawater and sediment collected from 3000 m water depth at hydrostatic pressures ranging from 1 to 300 atmospheres. Changes in, and composition of, microbial communities will be monitored using molecular fingerprinting techniques.

3.V2005. CO2 sequestration:

3.V2005. Securite sociale:

3.V2005. Cortisol levels diminished in both mother and baby after terroristic attack: Imagine than range of these problems in Srbija after 78 days of bombarding.

3.V2005. Soil quality threat to EU farming:
In OU’s T206 it says VOC and SO2 travels thousands of km through air therefore American pollution hungers EU soil.

3.5.2005. adrenal :, more adrenal, disease : adrenal and chronic fatigue syndrome: cure of cfs: elimination of salt. /Me: I noticed if you have a plate with just one part salted and you do not know which part of plate is and you eat with metal spoon, you accelerate your move /facial and hand/, after you take a bite with salted food. Check for Parkinson disease treatment .../

4.5.2005. circadian clock found in cardiovascular system:
Applications? Not wearing the ticking watch?

4.5.2005. Parents attack teachers in British schools: /Me: I repeat, this would not happen two decades ago. Global warming and pollution on airvalves compromised /Gaus statistics of majority within the range of normality, ie, majority of results in experimental model, is it 73percent or 63 percent?/, controlable entropy every brain of human society man has/.

4.5.2005. Law to protect criminals of fraud:

4.5.2005. some research on sugar:

4.V2005. PV on roofs Britain: ...cover electricity needs...
FAQs How much can photovoltaics really produce in Britain? The DTI have estimated that solar panels installed on buildings have the potential to provide all the electricity that Britain currently uses, however that would mean photovoltaics on most south facing roofs which is unlikely in the near future.

4.V2005. energy: solar renewable england

4.V2005. nuclear energy Britain:

4.V2005. A boy finds live snake in cereal packet:
What a story. At least this snake maybe want to be vegetarian and I respect he for that.

5.V2005. Electric car to do speed record: /Me:In T206 they claim the electric car from the beginning of twentieth century was going by speed of 120 km/h /.

5.V2005. Future technology and envirovment;

5.V2005. free trade and WTO:

6.V2005. sulphur dioxide: SO2

6.V2005. house music and the rest: /Me: on live instruments all, clean all, that is paradise of zero gravitation clubs/.

6.5.2005. Ovarian cells developed from cells:
stem menopauza, it will be reversed!!!

7/5/2005. Barcelona:
tips worth checking... /Me, personal : that is when I didnt got the visa for Israel, I went in June in Barcelona and Amsterdam/.

7.V2005. population:

7.V2005 REACH ProAnima, francais and English, needs translation in other languages as well. Thank you ProAnima for your fantastic effort: Thank you, dr. Claude Reiss for your expo in scientific manner:

Dernières Infosde Pro Anima

Evaluation de la toxicité scientifique des pesticides, des médicaments, des additifs alimentaires et autres produits chimiques
Contribution au projet REACH (Régulation, Evaluation et Autorisation des Produits Chimiques) de la Commission Européenne, présentée par le comité scientifique de l'ONG "Santé Sans Frontières". Adresse temporaire c/o Pro Anima ; 16 rue Vézelay ; 75008 Paris ; France. Auteur correspondant : Dr Claude Reiss (mel :
La Commission européenne (CE) a raison de vouloir évaluer les quelque 100 000 produits chimiques fabriqués par l'homme et auxquels nous sommes exposés, pour leurs effets sur notre santé et notre environnement (1). Cependant, le fait que le projet REACH prévoit que ces évaluations seraient effectuées aux frais du fabricant (2), qu'elles impliqueraient le sacrifice d'un très grand nombre d'animaux et qu'elles ne seraient pas terminées avant plusieurs décennies au moins, est une cause d'inquiétude pour les parties intéressées. Les industriels craignent pour leur compétitivité et leurs marges, les défenseurs des animaux s'élèvent contre ce qu'ils considèrent le plus vaste projet d'empoisonnement jamais organisée, impliquant des centaines de millions d'animaux, et les défenseurs de l'environnement veulent obtenir l'identification et le retrait des produits toxiques au plus vite, chaque jour perdu entraînant la disparition définitive d'espèces végétales ou animales et des pollutions irrémédiables ou très persistantes des ressources naturelles. Mais ce sont surtout les associations de consommateurs, de protection de la famille et les organismes dont le but est de venir en aide aux malades et de préserver la santé humaine (cancer, démences, allergies), qui s'élèvent avec le plus de véhémence contre le projet, à cause de l'inadéquation de la méthode envisagée pour l'évaluation de la toxicité des 100 000 substances (3). Certains de ces groupes mettent en question la validité pour l'homme d'évaluations de risques effectuées sur des animaux. Ils affirment que les observations d'effets toxiques chez une espèce ne sont valables que pour cette espèce, et que l'extrapolation de cette observation à une autre espèce (l'homme en particulier), est loin d'être fiable. Ils en veulent pour preuve l'évolution des données de statistique sanitaire (mortalité, morbidité) depuis l'introduction des produits chimiques dans notre environnement (en gros, depuis la fin de la seconde guerre mondiale), qui confirmerait l'impact de ces produits sur la santé humaine.
On voit que le projet REACH fait contre lui l'unanimité des parties intéressées, pour des raisons diverses. Pourtant, l'objectif d'évaluer sérieusement les risques des substances chimiques qui nous environnent ou que nous absorbons, est une priorité absolue et doit aboutir à tout prix. La présente contribution est un réexamen des conditions de mise en uvre des évaluations, prenant en considération les intérêts légitimes de toutes les parties intéressées.

Au cur de la controverse se trouve le procédé retenu pour l'évaluation des risques. REACH envisage le recours à l'expérimentation animale. Il est frappant d'observer d'un côté les progrès énormes effectués depuis un siècle par les industries chimique, pétrochimique, agrochimique et pharmaceutique dans le développement de produits hautement élaborés nécessitant des recherches de haut niveau, tandis que les procédés que la CE veut mettre en uvre pour évaluer les risques de ces produits sont très exactement les mêmes qu'il y a 150 ans et dépendent encore exclusivement d'études sur des animaux. Il convient de se demander si les progrès scientifiques récents ne pourraient pas générer des méthodes de test plus adaptées, capables de répondre aux attentes des diverses parties intéressées : moins cher, plus vite, sans animaux et surtout valable pour l'homme. Pour répondre à cette interrogation, nous examinerons ci-dessous les sept points suivants :
1) La nécessité d'évaluer les risques chimiques. L'examen de l'évolution des statistiques de santé humaine au cours de ces dernières décennies montre-t-il des tendances inquiétantes, par exemple, une augmentation de l'incidence des maladies majeures ? Si oui, quelles proportions peuvent être attribuées à une prévention insuffisante et aux produits chimiques fabriqués par l'homme ?
2) Les tests actuels permettent-ils une évaluation fiable pour l'homme ?
3) Y a-t-il de meilleures méthodes pour évaluer les risques toxiques ? Ces méthodes pourraient-elles être appliquées sans délai ?
4) L'évaluation du risque toxique par des procédures scientifiques (Toxicologie Scientifique, " TS ").
5) Les avantages de la TS par rapport aux procédures basées sur l'animal.
6) Les avantages de la TS pour les parties intéressées.
7) Mise en uvre de la TS dans l'UE.
1) Statistiques de morbidité et de mortalité dans l'UE : des tendances alarmantes.
L'espérance de vie dans les pays de l'UE est élevée, mais les taux de morbidité le sont aussi. Plusieurs millions de citoyens européens souffrent de maladies neurodégénératives graves (maladies d'Alzheimer et de Parkinson, sclérose en plaques, autisme, etc.). Bien que pour la plupart de ces maladies, l'augmentation du nombre de cas soit corrélée grossièrement avec l'allongement de l'espérance de vie, cette augmentation rapide (sclérose en plaques en particulier) est observée aussi parmi les personnes âgés de 20 à 40 ans et même chez les enfants (autisme). La montée la plus forte de morbidité et de mortalité a, cependant, été observée pour les cancers. En France, par exemple, depuis 1990, le cancer est devenu la première cause de mortalité chez les personnes âgées de 35 à 65 ans. Pour la classe d'âge des 45-49 ans, la proportion de morts dues à tous les cancers excepté celui du poumon a été multipliée par six entre 1950 et 1980 (par dix pour le cancer du poumon). 300 000 nouveaux cas de cancers sont diagnostiqués chaque année, avec une augmentation importante des cas vraisemblablement liés aux hormones : une femme sur treize était affectée du cancer du sein en 1970, une sur sept aujourd'hui.
Il est généralement admis que 5 à 10 % des cancers sont liés à des défauts génétiques. Ainsi, les facteurs exogènes, en particulier le style de vie (tabagisme, alcool, excès alimentaires, stress, etc.) et les produits carcinogènes présents dans notre alimentation et dans notre environnement sont responsables de neuf cancers sur dix. Comme les comportements à risque tendent à diminuer et que, par contre, le nombre et la quantité de produits chimiques nouveaux, donc de carcinogènes environnementaux, ne cesse d'augmenter, il est certain que ces derniers sont les principaux coupables des 1,7 millions de nouveaux cancers diagnostiqués dans les pays de l'UE chaque année. Ceci est une preuve claire que ces produits n'ont pas été testés pour leur potentiel carcinogène, ou bien, qu'ils ont été testés par des méthodes qui n'ont pu détecter ce danger.

On voit donc que le projet d'évaluation des risques chimiques est d'une urgente nécessité, et doit mettre en uvre des méthodes fiables. Pour évaluer l'efficacité de ces méthodes, examinons leurs performances dans le domaine où elles sont appliquées avec le plus de soin : l'évaluation de la toxicité des médicaments. Bien que le développement de n'importe quel médicament suppose des années de recherche et des batteries de tests, les effets secondaires de médicaments sont la quatrième cause de mortalité dans l'UE, provoquant 20 000 décès annuellement en France et quelque 120 000 dans l'UE en entier.
Il est donc indiscutable que les méthodes de test actuelles sont incapables de protéger notre santé. Quelles sont ces méthodes ? Comme requis par la loi, les tests de toxicité en général et pour les médicaments en particulier, doivent être effectués sur des animaux, c'est-à-dire des "modèles" dont on pense qu'ils présentent des réactions biologiques similaires à celles des humains.
2) Le recours au supposé modèle animal pour les problèmes de santé humaine est-il basé sur des principes raisonnables ?
Il y a une preuve simple et claire du fait qu'aucune espèce animale ne peut être prise comme modèle biologique fiable d'une autre. Une espèce est définie par son isolement reproductif, ce qui signifie que les membres d'espèces différentes ne peuvent pas se croiser. Cela est la conséquence du fait qu'une espèce donnée a un patrimoine génétique unique, qu'il s'agisse du nombre, de l'organisation et de la structure des chromosomes, ou de la régulation et du contrôle de l'expression génétique. La biologie moderne a mis en évidence que le patrimoine génétique d'un individu détermine les activités biologiques précises de ses cellules, tissus et organes. Ainsi, les individus d'espèces différentes ont des patrimoines génétiques différents et présentent donc des activités biologiques différentes, pouvant, selon, paraître similaires, différentes ou opposées à celles d'une autre espèce. Du fait de ce comportement biologique aléatoire, l'affirmation que les membres d'une espèce donnée peuvent se substituer comme modèles biologiques fiables pour une autre espèce est donc fausse.
En particulier, l'hypothèse que les résultats obtenus chez certains mammifères seraient applicables aux humains est non fondée et compromet sérieusement la santé humaine. Considérons, par exemple, le chimpanzé, notre parent le plus proche en termes évolutifs. Exposé au virus de l'immunodéficience humaine (VIH), le chimpanzé ne développe pas de maladie - chez les humains, il provoque le SIDA. Si on lui injecte le virus de l'hépatite B, un chimpanzé sur dix peut développer une forme atténuée d'hépatite et il récupérera rapidement - chez les humains, ce virus provoque une hépatite chronique et parfois le cancer du foie. Et, quand on lui injecte le virus Ebola, le chimpanzé meurt de fièvre hémorragique, comme les humains. En d'autres termes, le meilleur modèle animal se comporte d'une manière opposée, différente ou identique aux humains, face à un facteur donné. Personne ne pourrait avoir prévu ces résultats, qui ne peuvent être obtenus qu'après observation chez les deux espèces. Tester sur les modèles animaux est donc inutile au mieux, dangereux au pire, parfois fatal pour les humains : le scandale français du sang contaminé a eu lieu parce que les "experts", notant que le chimpanzé ne présentait pas de réaction, ont approuvé la mise sur le marché de ce sang.
Une estimation conservatrice du nombre de morts en France, résultant de cette méthodologie imparfaite d'évaluation de la toxicité des médicaments et produits carcinogènes seuls, est de 100 000 à 120 000 par an. En supposant que des taux similaires per capita soient valides dans les autres nations de l'UE, quelque 600 000 à 750 000 citoyens européens mourront prématurément année près année, à cause des effets secondaires des médicaments et des produits carcinogènes présents dans notre environnement.
3) Comment évaluer correctement le risque toxique pour les humains ?
Recourir aux animaux pour évaluer les risques toxiques pour les humains nous ramène à des temps médiévaux, quand c'était la seule manière d'avoir une vague indication du risque. A présent, la révolution scientifique nous propose des moyens beaucoup plus fiables. Cette toxicologie scientifique se comprend à partir de deux remarques de base.
Premièrement, la toxicologie est la science de la vie (biologie) dans un environnement de produits toxiques (xénobiotiques). Au cours du demi-siècle passé, la biologie a fait des progrès sans précédent, s'éloignant de l'empirisme vers la science et, même, vers une science exacte quand on en vient à la biologie cellulaire et moléculaire. La toxicologie peut bénéficier des concepts, méthodes et outils développés dans cette biologie moderne et ainsi obtenir le statut d'une science presque exacte.
Deuxièmement, c'est dans la cellule que la vie commence. Il n'est donc pas surprenant (et c'est entièrement soutenu par la biologie moderne) que les réponses à pratiquement tous les problèmes biologiques doivent d'abord être recherchées au niveau de la cellule. Les maladies humaines ont presque toutes une origine cellulaire, que la cause soit endogène (dans l'organisme) ou exogène (hors de l'organisme). Cela est vrai pour le cancer, les neuropathologies et les maladies cardiovasculaires, pour citer les maladies les plus fréquentes et graves dans les pays de l'UE. Il s'ensuit que les dommages causés à une cellule par une substance toxique est la première étape des maladies.
L'étude des cellules humaines dans l'environnement de produits toxiques sera donc la première étape pour une évaluation fiable de la toxicité pour les humains. La biologie moderne a aussi fait des progrès impressionnants dans l'étude des systèmes intégrés au niveau du tissu, de l'organe et systémique. Des méthodes non invasives (diverses tomographies, tests fonctionnels des activités biochimiques dans les organes, etc.) permettent l'évaluation complète du risque moléculaire et cellulaire de substances auxquelles les consommateurs sont fortement exposés (médicaments, additifs alimentaires, pesticides, etc.).
4) Toxicologie scientifique ("TS").
Notre objectif ici n'est pas de mettre en avant un programme scientifique détaillé de TS mais d'esquisser, pour une large audience intéressée, les grandes lignes de la TS moléculaire et cellulaire, en nous basant sur quinze années d'expérience dans ce domaine. En fait, non seulement certains des scientifiques qui ont contribué à ce rapport ont été actifs dans la réalisation de recherches et le développement de méthodes et d'outils pour la TS, mais ils ont aussi organisé des workshops internationaux destinés à réunir des spécialistes du monde entier dans leur domaine particulier de la toxicologie moléculaire et cellulaire -notamment, le Premier workshop européen de toxicologie moléculaire, Sophia Antipolis (France) 1996, le deuxième wokshop européen de toxicologie moléculaire, Paris, 1999)- et publié les comptes rendus de ces workshops : Molecular Toxicology, 1997 (VSP publishing, Reiss, Parvez et Labbe éditeurs), Molecular Responses to Xenobiotics, 2001 (Elsevier publishing, Parvez, Reiss et Labbe éditeurs) et le numéro spécial de Toxicology 153 (2000, nos 1-3, éditeurs invités Parvez et Reiss).
La toxicité peut provoquer des réponses aiguës et systémiques ; ces réponses peuvent être retardées du fait d'une accumulation de dommages mineurs qui arrivent finalement à surmonter la défense cellulaire et les mécanismes de réparation, ou bien, parce que le développement de la maladie est long. Un exemple typique de ce retard est le cancer, car il faut en moyenne cinq à dix ans entre le déclenchement de la prolifération d'une cellule et le diagnostic de la tumeur. Les états neurodégénératifs sont aussi très longs à apparaître. D'où la nécessité d'évaluer les réponses toxiques à la fois à court et à long terme.
Les études cellulaires sont idéalement adaptées à cette fin. Elles sont réalisées idéalement sur des cultures primaires, mais les lignées cellulaires établies permettent des examens préliminaires faciles. Un complément intéressant aux méthodes décrites ci-dessous est l'évaluation in silico des effets toxiques d'une molécule, dérivés de sa structure chimique (relation structure -activité), qui est de plus en plus fiable dans la prévision des activités biologiques néfastes de la molécule avant même qu'elle n'ait été synthétisée.
4.1 Toxicologie moléculaire et cellulaire.
4.1.1 Métabolisation du xénobotique (substance d'origine non biologique). Pour enter dans la cellule, le xénobiotique doit traverser des barrières lipidiques ou aqueuses et doit parfois être métabolisé à cette fin. Cela peut être effectué en activant l'expression de divers gènes codant pour des enzymes de métabolisation spécifiques (les monooxygénases, y compris les membres de la famille du cytochrome P450, les acétyltransférases, les époxyde hydrolases, les glutathio-S-transférases, les méthyltransférases, les sulfotransférases, les UDP-glycosyltransférases, etc.) des facteurs de transcription nucléaires (comme le récepteur PRX activé par une majorité de médicaments et impliqué dans de nombreux effets secondaires de médicaments), des transporteurs de xénobiotiques (métallothionéines, famille de la glycoprotéine-P), etc. Les métabolites obtenus doivent être soigneusement identifiés, car certains sont très toxiques, même si le xénobiotique non métabolisé ne l'est pas. Comme les principales cibles du xénobiotique sont le rein et le foie, les cellules de ces organes doivent être testées en premier. Plusieurs méthodes permettent de le faire : le test in vitro de l'activité enzymatique des gènes impliqués ; les puces à ADN (kits disponibles dans le commerce), qui permettent le contrôle de l'expression d'un grand nombre de ces gènes ; l'identification des métabolites par spectrométrie de masse ; etc.
4.1.2 Evaluation de la toxicité intracellulaire. Une fois que le xénobiotique ou son métabolite est entré dans la cellule, l'effet sur cette dernière et sa descendance doit être contrôlé. En réponse à une agression, même modérée, la cellule mobilisera une série de gènes, soit pour se protéger soit pour réparer le dommage.
De nombreux gènes (de stress ou d'enzymes de réparation) sont connus et peuvent être recrutés comme "reporters" : ils fournissent des informations sur la cible du xénobiotique, l'étendue du dommage et la capacité de la cellule à le surmonter. Les reporters permettent aussi de contrôler le devenir de la cellule exposée à diverses doses du produit, nous informant sur sa capacité à survivre et comment elle va faire face au produit à long terme. A présent, des cellules chargées de gènes reporters sont disponibles dans le commerce, permettant la mise en évidence rapide et peu coûteuse de stress (y compris oxydatif), de divers types de dommages à l'ADN, de dommages à la membrane, etc., en réponse au xénobiotique testé.
L'inconvénient des reporters est la nécessité de deviner le(s) gène(s) ciblé(s) par le xénobiotique. Ce problème est surmonté avec les puces à ADN portant des centaines ou des milliers de gènes connus pour être impliqués dans la réponse toxique (toxicogénomique). Par des manipulations biochimiques standard, l'expression de chacun de ces gènes peut être visualisée. Les puces permettent d'observer la transcription simultanée, dans le noyau cellulaire, de tous les gènes présents sur la puce, que ces gènes soient stimulés, réprimés ou non affectés par le xénobiotique.
Les puces à ADN sont actuellement les outils de pointe pour suivre la première partie - la transcription - de l'expression génique. Pour avoir une vue complète de l'effet du xénobiotique sur l'expression génique, la deuxième partie de cette expression - la traduction - au cours de laquelle le produit du gène est réellement synthétisé, doit aussi être suivie. Cela peut être fait avec les outils de la toxicoprotéomique (gel 2D d'électrophorèse capillaire, puces de protéines, spectrométrie de masse et de nombreuses nouvelles méthodes en développement rapide). La toxicoprotéomique rend compte des modifications de la protéine induites par le xénobiotique (chimiques ou structurales), les modifications des processus protéolytiques, l'agrégation etc., modifications qui ont été identifiées récemment comme des stades importants dans de nombreuses maladies graves (troubles neurodégénératifs, certaines démences, diabète de type 2, etc.).
Les effets génotoxiques des xénobiotiques doivent être identifiés et contrôlés avec une attention particulière, car l'échec de cette évaluation est le principal facteur responsable de la montée importante de l'incidence du cancer observée ces 50 dernières années. Les mutations de l'ADN peuvent être contrôlées par de nombreuses techniques (directement sur l'ADN : précisément (séquençage) ou grossièrement (test "Comète") ; ou indirectement en contrôlant l'expression des gènes de réparation de l'ADN). La tumorigenèse est favorisée par la mutation ou l'inactivation de gènes impliqués dans la régulation de la croissance et de la division cellulaire. Ces mutations dérèglent le contrôle de la mort cellulaire programmée, qui se fait normalement en réponse aux facteurs de croissance, de la migration cellulaire, etc. Des puces à ADN déjà disponibles permettent de caractériser le statut de la transcription de plusieurs centaines de gènes impliqués dans la tumorigenèse quand la cellule est exposée à un xénobiotique.
Les événements carcinogènes peuvent aussi être induits par des mécanismes non génotoxiques se produisant à diverses étapes (points de contrôle) du cycle cellulaire (division) ou au niveau de l'organisation supérieure du matériel génétique (chromatine). Les dénommés "suppresseurs de tumeurs" comme, par exemple, la célèbre protéine p53, un des gardiens du génome, présentent un grand intérêt. Cette protéine contrôle l'intégrité du matériel génétique de la cellule. Si un événement mutagène se produit, p53 interrompt le cycle cellulaire jusqu'à ce que le dommage ait été réparé. Si la réparation n'a pas pu être faite en quelques heures, p53 forcera la cellule à l'apoptose (suicide), empêchant la transmission du dommage à sa descendance. Les xénobiotiques qui endommagent p53 (ou d'autres suppresseurs de tumeurs), soit en mutant son gène ou par modification de sa structure, aboliront cette activité de gardien et les mutations pourront alors se propager à la descendance de la cellule et, éventuellement, induire une prolifération cellulaire incontrôlée. Plus de la moitié des tumeurs solides portent des formes inactives de p53. De nombreux kits commerciaux sont disponibles pour contrôler l'état des suppresseurs de tumeurs au niveau de la transcription ou de la protéine, en particulier pour les cancers dont on pense qu'ils dépendent d'hormones (cancer du sein et signalisation du récepteur des oestrogènes, cancer de la prostate et signalisation des androgènes). Des puces à ADN sont aussi disponibles pour contrôler l'expression, en présence d'un xénobiotique, de centaines de gènes humains impliqués dans les étapes majeures de la tumorigenèse, de la dérégulation des voies de la croissance et de la division cellulaire, la réponse au dommage de l'ADN, la stabilité et la réparation du génome, de l'adhésion cellulaire, l'invasion, la métastase, l'angiogenèse, etc.

Les xénobiotiques cytotoxiques ciblent l'organisation de la cellule, son équipement, son métabolisme, etc. Cette toxicité est souvent signalée par l'expression intense des gènes de stress (en particulier du stress oxydatif). Les cellules répondent initialement en produisant des "chaperones" et d'autres enzymes pour se protéger de l'action du xénobiotique. La gravité et la longueur de l'exposition peuvent stimuler plus ou moins de réponses cellulaires globales, telles que l'arrêt de la croissance, la sénescence, la nécrose, la mort cellulaire par apoptose et même la prolifération cellulaire. Par exemple, certains xénobiotiques peuvent déclencher la voie de l'apoptose impliquant la famille de gènes Bcl2. Les protéines correspondantes s'oligomérisent et s'insèrent dans la membrane mitochondriale, induisant la libération de son contenu (y compris la famille CARD), dont certains éléments déclenchent la mort cellulaire. La cytotoxicité peut être établie en contrôlant l'expression d'une longue liste de gènes de ménage et de gènes impliqués dans la nécrose, l'apoptose, l'arrêt de croissance, la sénescence, etc.
Les méthodes mentionnées jusqu'à présent peuvent être appliquées à n'importe quel type de cellule, mais celles des organes les plus exposés aux xénobiotiques (foie, rein, peau) doivent être évaluées en premier.
Des méthodes spécifiques existent pour l'évaluation d'une variété de xénobiotiques qui ciblent des fonctions biologiques particulières. En voici une courte liste :
La toxicité reproductive peut être contrôlée au niveau cellulaire par l'étude de l'activation des récepteurs hormonaux présents à la surface de cellules spécifiques. Par exemple, les "proliférateurs endocriniens" peuvent mimer les hormones naturelles et induire de façon excessive le signal spécifique d'une hormone, ou saturer des récepteurs et ainsi empêcher l'accès à l'hormone normale et la délivrance de son signal. Les xénobiotiques, y compris une large classe de pesticides, qui peuvent produire des anomalies dans les organes reproducteurs mâles ou favoriser des tumeurs dans les tissus et les organes qui sont sous contrôle hormonal (sein, ovaire, prostate), peuvent être identifiés dans des cultures de cellules prélevées de ces organes et tissus.
La toxicité développementale (y compris la tératogenèse) des xénobiotiques ciblant le cycle cellulaire, les facteurs d croissance ou les composants cellulaires impliqués dans la signalisation du développement (classes d'ARN, composants de la chromatine, etc.), peut être évaluée en contrôlant l'interaction du xénobiotique avec ces composants moléculaires de la cellule. Des puces à ADN sont disponibles pour contrôler l'action des xénobiotiques sur de nombreux gènes humains impliqués dans la régulation des phases de cycle (cyclines, kinases dépendantes de la cycline, et leurs régulateurs : inhibiteurs, phosphatases et kinases).
La neurotoxicité peut être la conséquence de l'action d'un xénobiotique sur les molécules impliquées dans la communication neuronale - une majorité d'insecticides ciblent ces molécules ! Plusieurs méthodes standard permettent d'évaluer ce type de toxicité sur les cellules neuronales en culture. Les signaux électrochimiques encodés le long d'un neurone, ou d'un neurone à l'autre, ont pour intermédiaire trois classes de canaux ioniques (canaux passifs, qui maintiennent le potentiel membranaire de repos ; canaux à commande chimique qui reconnaissent les neurotransmetteurs et initient un potentiel d 'action ; et canaux voltage-dépendants qui propagent le potentiel d'action) ; et deux larges classes de neurotransmetteurs (ceux agissant directement sur les canaux ioniques à commande chimique et les faisant s'ouvrir, et ceux agissant indirectement et plus lentement , impliquant les récepteurs couplés à la protéine G et la production de messagers secondaires). Les puces à ADN portant les gènes des canaux ioniques et des transporteurs de neurotransmetteur (y compris les neurotrophines, que l'on pense jouer un rôle important dans le développement neuronal) sont disponibles pour contrôler l'effet d'un xénobiotique sur ces acteurs essentiels en neurobiologie.
Les agents neurotoxiques peuvent aussi cibler les cellules neuronales en affectant leur capacité à synthétiser des protéines dans leur conformation native. Les protéines mal conformées tendent à s'accumuler dans ou autour de la cellule, à s'agréger et à former des fibres, des plaques ou des enchevêtrements qui forcent la cellule à commettre l'apoptose ou affectent la communication entre cellules. Le parkinsonisme (apoptose des cellules dopaminergiques), la maladie d'Alzheimer (dépôts de plaques amyloïdes et de fibres tau), la maladie de Creutzfeldt-Jakob (dépôt de prions) et plus de vingt autres formes de démence appartenant à la famille des "maladies conformationnelles" peuvent résulter de la production de protéines mal repliées. Les xénobiotiques peuvent cibler l'équipement cellulaire responsable de la production de protéines, soit directement (production de stress qui mobilise et isole excessivement les protéines de stress, comme les chaperones impliquées dans le repliement des protéines) ou indirectement (production non programmée de grandes quantités de protéines, ou prolifération cellulaire, qui diminue les ressources de la cellule pour la synthèse protéique et favorise ainsi le mauvais repliement des protéines). Tester des xénobiotiques pour leur capacité à induire le mauvais repliement des protéines, directement en utilisant les gènes reporters, est une nécessité urgente, si l'on considère le nombre important de patients âgés et, de plus en plus, les personnes de moins de 40 ans souffrant de maladies conformationnelles affaiblissantes.
Immunotoxicité : réponse inflammatoire. L'inflammation est à la fois la réponse normale du corps aux pathogènes et un intermédiaire clé des états maladifs tels que l'allergie, l'asthme et l'arthrite qui peuvent être induits par les xénobiotiques. La cascade de signalisation de la réponse inflammatoire est propagée par la sécrétion de petites glycoprotéines (cytokines) et leur liaison à des récepteurs de cellules cibles. Les puces à ADN portant des dizaines de gènes de cytokines humaines impliquées dans la réponse inflammatoire et des gènes de leurs récepteurs, sont disponibles, permettant la détermination simultanée des profils d'expression de ces gènes dans les cellules exposées à un xénobiotique imunotoxique donné.
Il existe des méthodes moléculaires pour évaluer la toxicité membranaire (modification de la polarité, taille et structure des couches lipidiques, etc.) et la toxicité épigénétique (méthylation de l'ADN, acylation ou phosphorylation de la chromatine, qui peuvent sérieusement affecter le programme d'expression génique), etc. A cause du polymorphisme de la population humaine, l'évaluation de la toxicité pour les classes de la population partageant des profils polymorphes peut être effectuée en utilisant des puces à ADN spécifiques de classe qui, par exemple, permettraient de lister les xénobiotiques particulièrement nuisibles, ou au contraire sûrs, pour les membres de la classe (toxicologie spécifique de polymorphisme et idiosyncratique). Par exemple, un polymorphisme humain important est trouvé dans la famille P450 des enzymes de métabolisation.
4.1.3 La toxicité de transduction de signal et intercellulaire cible les interactions cellule-cellule et cellule-matrice extracelullaire (jonctions communicantes), les processus endocrines et exocrines, etc. De nombreux types cellulaires reçoivent des signaux externes (des hormones) qu'ils transduisent (traduisent) par un mécanisme (voie de transduction de signal) en changeant leur comportement ou caractéristiques. Les récepteurs couplés à la protéine G, par exemple, forment une grande famille de récepteurs de surface impliqués dans la transduction de signal. Ils sont activés par une grande variété de signaux, y compris les produit chimiques et la plupart des médicaments. Le stress chimique peut activer la transduction de signal via le facteur de transcription NFkB, libéré par la phosphorylation de la famille de protéines inhibitrices IkB ou des sous-unités Rel. Une fois que NFkB est transloqué dans le noyau, il induit la transcription et l'expression de nombreux gènes tels que ceux encodant les cytokines, les molécules d'adhérence, les inhibiteurs d'apoptose, etc. La signaliation par la MAP kinase opère par une cascade de kinases qui activent aussi les facteurs de transcription d'une variété de gènes. La signalisation par la superfamille du TGFb entraîne l'inhibition de la croissance. A nouveau, les puces à ADN portant des centaines de gènes humains impliqués dans la transcription de signal peuvent contrôler l'action des xénobiotiques sur ces gènes.
Le devenir de la matrice extracellulaire (le substrat auquel les cellules s'attachent, via les molécules d'adhérence, pour aider à définir la forme, la structure et la fonction du tissu), quand elle est exposée à un xénobiotique, peut être contrôlé via le profil d'expression de molécules impliquées dans les interactions cellule-cellule et cellule-tissu, telles que les molécules d'adhérence cellulaire (intégrines, cadhérines, caténines, sélectines), les protéines de la matrice extracellulaire (lamines, fibronectine, fibrinogène), les protéases (métalloprotéinases de la matrice, sérine et cystéine protéinases, cathepsine) et les inhibiteurs de protéase (maspine). Les réseaux à ADN sont disponibles pour contrôler l'expression de centaines de gènes impliqués, fournissant des informations valables sur l'effet d'un xénobiotique sur les étapes primaires du développement du tissu et de l'organe.
En résumé, en utilisant les techniques basées sur la toxicité moléculaire, nous pouvons obtenir une vue claire du mécanisme par lequel la substance ou le produit est dangereux, à quelle dose la cellule peut résister et, le plus important, l'effet à long terme sur la cellule. L'expérience prend quelques jours en moyenne, peut être effectuée en grands ensembles parallèles de criblage (divers types cellulaires ou doses, par exemple), est relativement peu coûteuse, facile à standardiser et nécessite des quantités infimes du xénobiotique (important dans le test des médicaments). Les résultats sont quantitatifs (large plage de dose-réponse linéaire), reproductibles et, le plus important, sont valides pour l'espèce qui a fourni les cellules. Ces points représentent des avantages scientifiques et économiques certains, même si des compétences techniques de pointe sont nécessaires pour la plupart de ces méthodes.
4.2 Evaluation scientifique de la toxicité d'organe, de tissu et systémique
Nous estimons que l'évaluation du risque toxique par des approches moléculaires et cellulaires peut être étendue avec environ 90 % de fiabilité à l'organe, au tissu et au niveau systémique. Néanmoins, cette incertitude doit encore être réduite, en particulier pour les médicaments et les produits auxquels les consommateurs sont exposés pendant de longues périodes ou à des doses élevées (additifs alimentaires, pesticides). Dans certains cas particuliers, le produit peut être testé sur des tissus perfusés ou des tranches d'organe, afin de contrôler la réponse des cellules intégrées dans leur environnement normal. Du fait des problèmes de fourniture et de dégradation rapide des tranches, ces tests sont difficiles à effectuer en routine. Il est plus facile de s'en remettre aux méthodes non invasives sur des volontaires humains en conditions de test clinique strictes (avec consentement informé), pour contrôler l'effet du xénobiotique sur le tissu ou l'organe en fonctionnement in situ. Les techniques d'imagerie (MRI, PET, scan, etc.) ont une valeur particulière puisqu'elles permettent d'identifier l'organe ciblé par le xénobiotique et de visualiser le métabolisme et l'élimination du produit. Des informations complémentaires valables sur le fonctionnement d'organes particuliers peuvent être obtenues par les tests biochimiques et biomédicaux standard.
5) Avantages de la TS (toxicologie scientifique) par rapport à l'évaluation de la toxicité traditionnelle (recherche basée sur les animaux)
Comme montré précédemment, les réactions biologiques des individus d'une espèce donnée sont uniques. Les individus d'espèces différentes peuvent, à l'occasion, présenter des réponses grossièrement similaires quand ils sont exposés au même produit toxique, mais on ne doit jamais se laisser tromper par ces phénomènes de hasard. Premièrement, et le plus important, le mécanisme par lequel un produit induit une réaction pathologique peut être assez différent dans des espèces différentes. Parmi les médicaments utilisés, 60 % sont métabolisés, chez les humains, par le même membre de la famille des P450 (ce qui peut conduire à une activation du médicament synergique), mais plusieurs membres différents de la famille des P450 sont impliqués chez les singes, les chiens ou les rongeurs. Deuxièmement, les effets à long terme chez les humains sont impossibles à évaluer dans un espèce avec une espérance de vie plus courte. Chez les souris, le développement spontané du cancer commence à l'âge de 10 mois, alors que chez les humains il commence en général après l'âge de 40 ans, et les mécanismes qui favorisent le cancer sont très différents dans chaque espèce. La susceptibilité au cancer de différentes souches de souris peut varier jusqu'à cent fois, certaines souches tolérant, sans effets de maladie apparents, des doses d'oestrogène qui sont de nombreuses fois supérieures à celles qui rendent malades d'autres souches. Même si les réponses grossières dans deux espèces différentes se ressemblent sur le court terme, le mécanisme sous-jacent qui détermine le résultat à long terme est très vraisemblablement différent et peut donc aboutir à des résultats très différents, sur des années. Incidemment, notons qu'il serait naturellement inutile de réaliser une TS pour un espèce donnée sur des cellules d'une espèce différente.
6) Avantages pour les parties intéressées
L'avantage le plus évident serait la sécurité du consommateur. La TS permet de comprendre le mécanisme par lequel une substance produit ses effets toxiques, ce qui aide à prévoir ses effets à long terme. En identifiant les produits favorisant le cancer, la prévention en serait significativement améliorée. Nous estimons que les chiffres de morbidité du cancer seraient ainsi divisés par deux les trois à cinq années suivantes. L'évaluation fiable de la toxicité des médicaments pourrait sauver des dizaines de milliers de vies chaque année. Les substances neurotoxiques (80 % des insecticides sont neurotoxiques pour les insectes ; qu'en est-il pour les humains ?) pourraient être identifiées et retirées du marché, prévenant les dommages du développement neuronal des enfants - selon la FDA, l'insecticide roténone entraînerait de tels dommages. La détection et le retrait des proliférateurs endocriniens préviendrait à la fois le développement anormal des organes sexuels et de la plupart des cancers induits par les hormones (sein, ovaire, prostate).
Une sécurité du consommateur améliorée entraînerait le soulagement immédiat des coûts socio-économiques résultant des maladies, dont les taux sont présentement en plein essor dans les pays de l'UE.
Les avantages des évaluations par la TS pour l'industrie sont nombreux. Les expériences de TS prennent quelques jours en moyenne, peuvent être effectuées dans de grands ensembles parallèles de criblage (avec divers types cellulaires ou doses, par exemple), sont relativement peu coûteuses, faciles à standardiser et nécessitent des quantités infimes du xénobiotique (important dans le test sur les médicaments). Les résultats sont quantitatifs (avec une large plage de dose -réponse linéaire), reproductibles et, le plus important, fiables et valides pour l'espèce examinée. De plus, la compréhension du mécanisme de l'effet toxique peut permettre aux chimistes de modifier le xénobiotique pour annuler ou réduire sa toxicité (avec l'aide des modèles de relation structure-activité, par exemple) ou pour améliorer sa qualité - et l'image du fabriquant ! Comme les tests de TS sont facilement standardisés et indépendants de paramètres subjectifs, ils restent valides à travers les frontières politiques, ce qui permet la circulation sans limite des biens testés par TS parmi les pays de l'UE et à l'étranger.
Bien que des compétences techniques avancées soient nécessaires pour la plupart des méthodes de TS et que l'équipement de laboratoire requis soit coûteux, cela serait plus que contrebalancé par les avantages scientifiques, économiques et de santé publique.
Les procédures de TS s'appliquent aussi à d'autres espèces et peuvent donc être utilisées pour évaluer les toxicités environnementales dans toute espèce animale ou végétale.
Comme les procédures de TS évitent nécessairement les espèces "modèles", elles satisferaient aussi les associations de protection animale.
Enfin, la mise en oeuvre des méthodes de TS améliorerait l'image de l'UE, à la fois à l'intérieur des pays membres (les consommateurs seraient reconnaissants pour une meilleure protection de leur santé) et à l'extérieur, car l'Union pourrait montrer la voie d'une amélioration du traitement des problèmes de santé environnementale dans le monde entier.
7) Comment favoriser la mise en oeuvre rapide et pratique de la TS dans l'UE ?
Une stratégie pour introduire la TS pourrait être basée sur les étapes suivantes :
1. Elaborer un programme de TS détaillé. A cette fin, créer et financer un comité de spécialistes (nos organisations sont prêtes à apporter leur expérience).
2. Financer et mettre en place un laboratoire pilote de TS européen (par exemple, au centre de recherche conjointe).
3. Financer et former des toxicologues TS. Organiser un cours de formation de 6 à 8 mois dans le laboratoire pilote pour les étudiants de maîtrise et de post-maîtrise de tous les pays européens, avec des conférences et des cours donnés par les spécialistes leaders dans le domaine.
4. Encourager tous les pays de l'UE à mettre en place des laboratoires pilotes de TS pour une formation, assurée par des toxicologues TS professionnels ou, plus localement, des toxicologues déjà sensibilisés à la TS.
5. Encourager les initiatives industrielles de conversion aux méthodes de TS.
6. Publier des directives établissant que tout nouveau produit mis sur le marché doit avoir été testé par les méthodes de TS, aux niveaux moléculaire et cellulaire pour les produits pour lesquels l'exposition est limitée et au niveau du tissu ou organe (en particulier le foie et le rein) et systémique pour les produits pour lesquels l'exposition est importante (médicaments, additifs alimentaires, pesticides, etc.). Les produits déjà sur le marché devraient être testés par les méthodes de TS dans les trois à cinq ans. Ceux qui ne passeraient pas le test devraient être retirés.

(1) Livre blanc de la CE Stratégie pour une future politique chimique, publié en février 2001 par la Commission européenne, disponible sur
(2) Voir l'initiative de la CE SCALE (science, enfants, conscience, légal et évaluation) et le système REACH (enregistrement, évaluation autorisation de produits chimiques) disponible sur
(3) Communiqué de presse de la CE sur l'environnement et la santé, 11 juin 2003

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Scientific Toxicity Assessment of Pesticides,

Drugs, Food Additives and other Chemicals.

Contribution to REACH (Regulation, Evaluation and Authorization of Chemicals) EC body,
Presented by the Scientific board of the NGO "HEALTH WITHOUT FRONTIERS", temporary address c/o PRO ANIMA, 16 rue Vézelay F75008 Paris France, corresponding author at E-mail

European Union authorities are right in deciding that the 100,000 man-made chemicals to which we are exposed must be assessed for their adverse effects on our health and our environment (1). However, the prospect (2) that these assessments will be carried out at the manufacturers' expense, that they will involve a very large number of animals and that they will not be completed for several decades at least, is cause for concern (3). Those most concerned are consumer organisations and private charities whose aim it is to promote human health (see 4). Some of these groups have challenged the scientific validity of such observations and results, since they would be obtained from animal-based research, and contend that the adverse effects of chemicals can only be reliably assessed for the species tested and are irrelevant for any other species, humans in particular. They claim also that health statistics data fully support their case.
It is in fact striking to observe the huge progress made over the past century by the chemical, petrochemical, agrochemical and pharmaceutical industries in the development of products, whilst the methods for assessing the risks of chemical products have remained almost unchanged and still depend exclusively on animal models. It is therefore timely, before starting risk assessments of the 100,000 chemicals, to carefully examine whether recent scientific progress, which has contributed more accurate testing methods, could provide benefits, especially by improving consumer safety. To this end, we will examine the following seven topics:
1) Human health statistics gathered over the past few decades: do these statistics point towards negative health trends, eg, an increase in the incidence of major diseases? If so, what proportions can be ascribed to insufficient prevention and to man-made chemicals?
2) Are the testing procedures at present in use satisfactory for the reliable prevention of major diseases?
3) Are there better methods for assessing toxic risks? Can such methods be applied without delay?
4) Science-based toxic risk assessment (SBT).
5) Merits of SBT over animal-model-based procedures.
6) Merits and benefits of SBT for interested parties.
7) SBT in the EU
1) Morbidity and mortality statistics in the EU: alarming trends
Despite the fact that life expectancy in EU countries is high, this benefit is offset by high morbidity rates. Several million EU citizens suffer debilitating neurodegenerative conditions (Alzheimer's and Parkinson's disease, multiple sclerosis (MS), autism etc). Although for most of these diseases the increase in the number of cases correlates roughly with the increase in life expectancy, a rapid increase in neurodegenerative conditions (MS in particular) has been observed among people between 20 and 40 years of age and even in children (autism). The steepest rise in morbidity and mortality has, however, been seen in cancer. In France, for instance, the number-one cause of death since 1990 for people aged 35 to 65 years has been cancer. The proportion of deaths due to all cancers, except lung cancer, among people aged 40 to 45 years has increased six-fold between 1950 and 1980, and 300,000 new cancers are diagnosed annually, with a significant increase in the number of cancer cases likely to be linked to hormones. One woman out of thirteen was affected by breast cancer in 1970. Today, it is one in seven.
It is generally agreed that 5-10% of all cancers are linked to genetic defects, and this figure has remained fairly constant. Hence, exogenous (outside) factors, especially lifestyle (smoking, alcohol, dietary excess, etc) and carcinogenic (cancer-promoting) products present in our food and in our environment are responsible for nine out of ten cancers. Since lifestyle has steadily improved over the past decades (less smoking, more modest and balanced diets), it is likely that environmental carcinogens are now the main culprits responsible for causing the 1.7 million new cancers diagnosed in EU countries annually. This is clear evidence that these products have either not been tested for their carcinogenic potential or have been tested by methods which have failed to detect this danger.
To assess the efficacy of these methods, let us examine how they perform in an area where they are applied most stringently: the assessment of prescription drug toxicity. Despite the fact that many years of research are invested in any particular drug development and testing, adverse drug reactions (side effects) rank as the fourth leading cause of death in the EU, claiming 20,000 lives annually in France (and some 120,000 lives in the EU as a whole).
It is obvious, then, that current testing methods are failing to protect public health efficiently enough. What are these methods? As required by law, toxicity testing in general, and for prescription drugs in particular, must be performed on animals, ie, 'models' which are believed to display biological reactions similar to those of humans. It is therefore worthwhile analysing the relevance of the 'animal model' concept in relation to human health.
2) Is resorting to animal models for human-health issues based on rational principles?
There is remarkably simple yet clear proof that no animal species can substitute as a reliable biological model for another species. A species is defined in terms of its reproductive isolation, meaning that members from different species cannot interbreed. This is because a given species has its own unique genetic make-up (from number, organisation and structure of chromosomes, through to regulation and control of gene expression). Modern biology has clearly demonstrated that the genetic make-up of an individual determines the precise biological activities of its cells, tissues, and organs. Hence, individuals from different species have different genetic make-ups and therefore display different biological activities, even if some appear similar. The statement that members of a given species can substitute as reliable biological models for other species is therefore invalid.
In particular, the assumption that results obtained in some mammalian species are valid for humans is unfounded and seriously compromises human health. Consider, for instance, the chimpanzee, our closest relative (in evolutionary terms). If exposed to the human immunodeficiency virus (HIV), the chimpanzee does not respond ; in humans it causes AIDS; if injected with the hepatitis B virus, one out of ten or so chimpanzees might develop a mild form of hepatitis and will recover quickly ; in humans, the virus causes chronic hepatitis and sometimes liver cancer; and the chimpanzee, when injected with the Ebola virus, dies of haemorrhagic fever, as do humans. In other words, the best animal model ever behaves in an opposite, different or identical way to humans, depending on the challenging factor. Nobody could have forecasted these results, which can only be arrived at after observing the test in both species. Testing animal models is therefore useless at best and is at worst dangerous, sometimes fatal, to humans: the French blood scandal occurred because 'experts', noting that the chimpanzee showed no response, approved of HIV-contaminated blood samples going onto the market.
A conservative estimate of the number of deaths in France, resulting from this flawed methodology of testing prescription drugs and carcinogenic products alone, ranges from 100,000 to 120,000 a year. Assuming that similar rates per capita are valid in other EU nations, some 600,000 to 750,000 citizens will die prematurely within the EU year after year, because of side effects of drugs and carcinogenic products present in our environement.
3) What is the basis of valid toxic risk assessment for humans?
Resorting to animals for assessing toxic risks in humans goes back to medieval times, as it was then the only way to get a vague indication of the risk. At present however, the scientific revolution provides us with far more reliable means for toxic risk assessment. This science-based toxicology builts on two basic remarks.
First, toxicology is the science of life (biology) in an environment of toxic products (xenobiotics). Over the past half-century, biology has made unprecedented leaps, moving away from empiricism and towards science, and even almost exact science when it comes to cellular and molecular biology. Toxicology can benefit from the concepts, methods and tools developed in such modern biology and thereby achieve also the status of an almost exact science.
Second, the cell is where life starts. It is therefore not surprising (and fully supported by modern biology) that the answers to practically all biological problems must first be sought at the level of the cell. Human diseases almost invariably have a cellular origin, whether the cause is endogenous (in the organism) or exogenous (outside the organism). This holds true for cancer, neuropathologies and cardiovascular diseases, to cite the most frequent and life-threatening diseases in EU countries. It follows that harm done to the cell by a toxic substance is the first step to diseases linked to the body's environment (including food, polluting substances etc).
The stage is thus set for Science-Based Toxicology (SBT), as opposed to the traditional toxicity assessment by means of animal models. SBT has its roots in modern molecular and cellular biology, from which it selects and adapts the methods and tools best suited for its goals.
The study of human cells in the environment of toxic products will therefore be the first step for reliable toxicity assessment in humans. Modern biology has also made impressive progress in the study of integrated systems at the tissue, organ and systemic levels. Non-invasive methods (various tomographies, functional testing of biochemical activities in organs etc) are available, allowing to complete molecular and cellular human-risk assessments of substances to which consumers are extensively exposed (prescription drugs, food additives, pesticides etc).
4) Science-Based Toxicology (SBT)
Our purpose here is not to advance a detailed scientific programme of SBT but to sketch for a wide and interested audience the main outlines of molecular and cellular SBT, based on fifteen years of experience in this field. Indeed, not only have some of the scientists who contributed to this report been active in carrying out research and developing methods and tools for SBT, but they have also organised international workshops aimed at bringing together world-class specialists in their own particular fields of molecular and cellular toxicology ; namely, First European Workshop in Molecular Toxicology, Sophia-Antipolis (France) 1996, Second European Workshop in Molecular Toxicology, Paris 1999) and published the proceedings of these workshops: Molecular Toxicology, 1997 (VSP publishing, Reiss, Parvez and Labbe editors), Molecular Responses to Xenobiotics, 2001 (Elsevier publishing, Parvez, Reiss and Labbe editors) and Special Issue of TOXICOLOGY 153 (2000, nos 1-3, guest editors Parvez and Reiss).
Toxicity responses can be acute and systemic; they can also be delayed, either because of an accumulation of minor damages, which manage finally to overcome cellular defence and repair mechanisms (a major cause of liver and kidney diseases) or because the development of the disease takes a long time following its induction. A typical example of this delay is cancer, as it takes on average five to ten years between the onset of the proliferation of a cell and the diagnosis of the resulting tumour. Neurodegenerative conditions follow a similar time-course. Hence the necessity to assess both the short- and long-term toxic responses.
Cellular studies are ideally suited to this end. They are best performed on primary cultures, but established cell lines allow for easy preliminary investigations. An interesting complement to the methods described below is the in silico evaluation of the toxic effects of a molecule, derived from its chemical structure (structure-activity relationship), which is increasingly reliable in forecasting the adverse biological activities of the molecule even before it has been synthesised.
4.1 Molecular and cell toxicology.
4.1.1 Metabolisation of the xenobiotic (substances of non-biological origin). In order to enter the cell, the xenobiotic has to cross lipid (fatty) or aqueous barriers and may need to be metabolised to that end. This can be done by activating the expression (forcing out) of various cellular genes, which may involve specific metabolising enzymes ; mono oxygenases, including members of the P450 family, Acetyltransferases, Epoxide Hydrolases, Glutathio-S-Transferases, Methyltransferases, Sulfotransferases, UDP-glycosyltransferases etc; nuclear transcription factors (like the PRX receptor activated by a majority of drugs and involved in many adverse drug effects); xenobiotic transporters (metallothioneines, P-glycoprotein family) etc. The resulting metabolites need to be carefully identified, since some happen to be highly toxic, even though the unmetabolised xenobiotic is not. Since primary targets of xenobiotics are the liver and the kidney, cells from these organs should be tested first. Methods: in vitro testing of the enzymatic activity of the involved genes; DNA chips (kits commercially available), which allow the monitoring of the expression of many of these genes; identification of metabolites by mass spectrometry; etc.
4.1.2 Intracellular toxicity assessment. Once the xenobiotic or its metabolite has entered the cell, the effect on the latter and its fate must be monitored. In response to even mild aggression, the cell will mobilise a series of genes, either to protect itself or to have the damage repaired.
Many members of the families of genes involved (stress genes and various repair enzyme genes) are known and can be recruited as 'reporters', which provide information on the target of the xenobiotic, the extent of the damage and the ability of the cell to overcome the damage. Reporters allow also to monitor the fate of the cell, exposed to various doses of the product, telling us about its ability to survive and how it will cope with the product in the long run. At present, reporter gene-loaded cells are commercially available, allowing the fast and inexpensive tracing of xenobiotics responsible for stress (including oxidative stress), various kinds of DNA damage, membrane damage etc.
The disadvantage with reporters is the necessity of guessing the gene(s) targeted by the xenobiotic. This problem is overcome with commercially available DNA chips, carrying hundreds or thousands of gene elements known to be involved in toxic response (Toxicogenomics). By standard biochemical manipulations, the expression of each of these genes can be individually visualised on the chip. DNA chips allow observation of the simultaneous transcription behaviour in the cell's nucleus of all genes present on the chip, whether the genes are stimulated, repressed or unaffected by the xenobiotic.
DNA chips are presently the ultimate tools for monitoring the first part, the transcription of gene expression. In order to have a full view of the effect of xenobiotic activity on gene expression, the second part of expression, translation, during which the gene product is actually synthesised, must also be monitored. This can be done with the tools of Toxicoproteomics (2D gel or capillary electrophoresis, protein chips, mass spectroscopy, and many new methods under rapid development). Toxicoproteomics account for the xenobiotic-induced protein modifications (chemical or structural), modifications of proteolytic processes, aggregation etc, which have been identified recently as representing important stages in many severe diseases (neurodegenerative disorders, dementia, diabetes type 2 etc).
Genotoxic activities of xenobiotics need to be identified and monitored with particular attention, since the failure to assess their effects accurately is the main factor responsible for the steep rise in cancer incidence observed over the past 50 years. These effects and activities can lead to DNA mutations, which can be monitored by a wealth of techniques (directly on DNA: precisely (sequencing) or roughly ('Comet' test); or indirectly, by monitoring the expression of DNA repair genes). Tumorigenesis is promoted by mutation or inactivation of genes involved in the regulation of cell growth and division. This leads to deregulation of pathways in charge of controlling programmed cell death, response to growth factors, cell migration etc. DNA chips are available which allow characterisation of the transcription status of several hundreds of the genes involved in tumorigenesis when the cell is exposed to some xenobiotic.
Carcinogenic events can also be induced by non-genotoxic mechanisms, occurring at various steps (check points) of the cell cycle (division) or at the level of the higher organisation of the genetic material (chromatin). Of particular interest are the so-called tumour suppressors, as, for instance, the much-celebrated protein p53, one of the 'guardians of the genome'. This protein has control over the integrity of the genetic material of the cell. If some mutagenic event has occurred, p53 will immediately interrupt the cell cycle until the damage has been repaired. If the repair has not been achieved within a few hours, p53 will force the cell into apoptosis (suicide), thereby preventing transmission of the damage to the cell's progeny. Xenobiotics targeting p53 (or other tumour suppressors), either by mutating its gene or by modifying its structure, will abolish the 'guardian' activity of the protein, so that mutations can carry over to the cell's progeny and eventually induce uncontrolled cell proliferation ; over half of solid tumours carry inactive forms of p53. Many commercial kits are available for monitoring the state of tumour suppressors and checkpoint gene expression, at the transcription or the protein level, especially for cancers thought to depend on hormones (breast cancer and oestrogen receptor signalling, prostate cancer and androgen signalling). DNA chips are also available for monitoring the expression, in the presence of a xenobiotic, of hundreds of human genes involved in the major steps of tumorigenesis, from deregulation of pathways in cell growth and division, DNA damage response, genome stability and repair, to cell adhesion, invasion, metastasis, angiogenesis etc.
Cytotoxic xenobiotics target the cell's organisation, its equipment, its metabolism etc. This toxicity is often signalled by intense expression of stress genes (in particular oxidative stress see 'reporter' gene section above). Cells initially respond by producing 'chaperones' and other enzymes to protect themselves from the xenobiotic's action. The severity and length of the exposure can elicit more global cellular responses, such as growth arrest, senescence, necrosis, cell death by apoptosis and even cell proliferation and carcinogenesis. The targets of cytotoxicity are the various cellular compartments and components, in particular mitochondria , the energy-factory of the cell which can trigger apoptosis. For instance, xenobiotics can trigger the apoptosis pathway involving the Bcl2 gene family. The corresponding proteins oligomerise and insert themselves into the mitochondrial membrane, inducing the release of its content (including the CARD family), some of which trigger cell death. Cytotoxicity can be established by monitoring the expression of a long list of housekeeping genes and genes involved in necrosis, apoptosis, growth arrest, senescence etc.
The methods mentioned so far can be applied to any type of cell, but those from organs most exposed to xenobiotics (liver, kidney, skin) should be assessed first.
Specific methods exist for the molecular assessment of a variety of xenobiotics which target particular biological functions. Here is a short list:
Reproductive toxicity can be monitored at the cell level, by, for instance, studying the activation by a xenobiotic of hormone receptors present at the surface of specific cells. As an example, 'endocrine proliferators' can mimic natural hormones and unduly induce the hormone-specific signal, or they can saturate specific hormone receptors and thereby preclude access to the normal hormone and delivery of its signal. Xenobiotics, including a large class of pesticides, which can induce abnormalities in male reproductive organs or promote tumours in tissues and organs which are under hormonal control (breast, ovary, prostate), can be identified in cultures of cells taken from these organs and tissues.
Developmental toxicity (including teratogenesis) linked to xenobiotics targeting the cell cycle, growth factors or cell components involved in development signalisation (classes of RNAs, chromatin components, etc.), can be assessed by monitoring the interaction of the xenobiotic with these molecular components of the cell. DNA chips are available for monitoring the action of xenobiotics on many human genes involved in the regulation of the cycle phases (cyclins, cyclin-dependent kinases and their regulators: inhibitors, phosphatases and kinases).
Neurotoxicity can be the consequence of the action of a xenobiotic on molecules involved in neuronal communication ; a majority of insecticides target these molecules! Several standard methods make it possible to assess this class of neurotoxicity on neuronal cells in culture. Electrochemical signals sent down the length of a neuron, or from one neuron to another, are mediated by three classes of ion-specific channels (passive channels, which maintain resting membrane potential; chemically gated channels which recognise neurotransmitters and initiate an action potential, which is then propagated by voltage-gated channel); and by two broad classes of neurotransmitters (those acting directly on chemically gated ion channels and causing them to open, and those acting indirectly and more slowly, involving G-protein coupled receptors and the production of secondary messengers). DNA chips carrying genes of ion channels and neurotransmitter transporters (including neurotrophins, which are thought to play an important role in neuronal development) are available for monitoring the effect of a xenobiotic on these essential actors in neurobiology.
Neurotoxic agents can also target neuronal cells by affecting their capacity to synthesise proteins in their native conformation. Misconformed proteins tend to accumulate in or around the cell, to aggregate and form fibres, plaques or tangles which force the cell to commit apoptosis (due to intracellular accumulation of misfolded proteins) or impair cell-to-cell communication (extracellular deposit of proteinaceous aggregates). Parkinsonism (apoptosis of dopaminergic cells), Alzheimer's disease (amyloid plaque and tau fibre deposits), Creuzfeld-Jacob disease (prion deposit) and more than twenty other forms of dementia belonging to the family of "conformational diseases" can result from the production of misconformed proteins by the cellular protein synthesis apparatus (see below). Xenobiotics can target this equipment, either directly (production of stress which excessively mobilises and secludes stress proteins, like chaperones involved in protein folding) or indirectly (unscheduled production of large quantities of proteins, or cell proliferation, which depletes the cell's resources for protein synthesis and thereby favours protein misfolding). Testing xenobiotics for their capacity to induce protein misfolding, which is straightforward using reporter genes, is an urgent necessity, considering the significant number of elderly patients, and more recently even people below forty years of age, suffering from debilitating conformational diseases.
Immunotoxicity: inflammatory response. Inflammation is both the normal response of the body to pathogenes and a key intermediate of disease states such as allergies, asthma and arthritis which can be induced by xenobiotics. The signalling cascade of inflammatory response is propagated by the secretion of small glycoproteins (cytokines) and their binding on receptors of target cells. DNA chips bearing tens of human cytokine genes involved in the inflammatory response, and of the genes of their receptors, are available, allowing simultaneous determination of their expression profiles in cells exposed to some immunitoxic xenobiotic.
Molecular methods exist to assess membrane toxicity (modification of polarity, size and structure of lipid rafts, etc) and epigenetic toxicity (xenobiotic-producing DNA methylation, acylation or phosphorylation of chromatin, which can seriously affect the programme of gene expression) etc. Because of the polymorphism of the human population, assessment of cellular toxicity for classes of the population sharing common polymorphic patterns could be made, using class-specific DNA chips, which would, for instance, allow one to list xenobiotics which are especially harmful, or conversely safe, for members of the class (polymorphism-specific and idiosyncratic toxicology). For example, an extensive human polymorphism is found in the P450 family of metabolising enzymes.
4.1.3 Signal transduction and intercellular toxicity target cell-to-cell and cell-extracellular matrix (gap junction) interactions, endocrine or exocrine processes etc. Many cell types receive external signals (from hormones) which they transduce (translate) by some mechanism (signal-transduction pathway) into changing their behaviour or characteristics. G-protein coupled receptors, for instance, form a large family of cell-surface receptors involved in signal transduction. They are activated by a large variety of ligands, including chemicals and most drugs. Chemical stress can activate signal transduction via the NFkB transcription factor, released by the phosphorylation of the inhibitory IkB family of proteins or the Rel subunits. Once NFkB translocates in the nucleus, it induces transcription and expression of many genes such as those encoding cytokins, adhesion molecules, inhibitors of apoptosis etc. MAP kinase signalling operates through a cascade of kinases which also activate transcription factors of a variety of genes. Signalling by the TGFb super-family causes growth inhibition. Again, DNA chips carrying hundreds of human genes involved in signal transduction can monitor the action of xenobiotics on these genes.
The fate of the extracellular matrix (the substratum to which cells attach via adhesion molecules on the cell surface to help define tissue shape, structure and function), when exposed to a xenobiotic, can be monitored via the expression profile of molecules involved in cell-to-cell and cell-tissue interaction, such as cell-adhesion molecules (integrins, cadherins, catenins, selectins), extracellular matrix proteins (lamins, fibronectin, fibrinogen), protease (matrix metalloproteinases, serine and cystein protinases, cathepsin) and protease inhibitors (maspin). DNA arrays are available for monitoring the expression of hundreds of the genes involved, providing valuable information on the effect of a xenobiotic on primary steps in tissue and organ development.
In summary, using techniques based on molecular toxicity, we can obtain a clear view of the mechanism through which the substance or product is harmful, at what doses the cell can resist and, most importantly, the long-term effect on the cell. The experiment takes a few days on average, can be performed in large parallel screening set-ups (various cell types or doses, for instance), is relatively inexpensive, easy to standardise and requires tiny amounts of the xenobiotic (important in drug testing). The results are quantitative (large range of linear dose-response), reproducible and, most significantly, are valid for the species which provided the cells. These points represent definite scientific and economic advantages, even though advanced technical skills are required for most of these methods.
4.2 Scientific assessment of organ, tissue and systemic toxicity
We estimate that the assessment of the toxic risk by molecular and cellular approaches can be extended with some 90% reliability to the organ, tissue and systemic level. Nevertheless, this uncertainty must be further reduced, especially for prescription drugs and products to which consumers are exposed for long periods of time or at high doses (drugs, food additives, pesticides). In special cases, the product can be tested in perfused (permeated) tissues or in organ slices, which allow monitoring of the response of the cells integrated in their normal environment. Owing to supply problems and rapid degradation of the slices, these tests are difficult to carry out routinely. It is much easier to rely on non-invasive methods, which allow the monitoring of human volunteers, under strict clinical test conditions (with informed consent), for the effect of the xenobiotic on the tissue or functioning organ in situ. Of particular value are imaging techniques (MRI, PET scan, etc), which allow one to identify the organ targeted by the xenobiotic, the metabolism and elimination of the latter. Valuable complementary information on the functioning of particular organs can be obtained by standard biochemical and biomedical tests.
5) Merits of SBT (science-based toxicology) over traditional (animal-based research) toxicity assessment
As shown above, the biological reactions of individuals of a given species are unique. Individuals from different species may occasionally display similar gross responses when exposed to the same toxic product, but one should never be misled by these chance phenomena. First and foremost, the mechanism through which a product induces some pathological reaction can be quite different in different species. Of the drugs in use, 60% are metabolised in humans by the same member of the P450 family (which can lead to synergistic drug activation), but several different members of the P450 family are involved in the case of apes, dogs and rodents. Secondly, long-term effects in humans are impossible to assess in species with a shorter life expectancy. In mice, spontaneous cancer development commences at the age of ten months, whereas in humans it usually starts after the age of forty, and the mechanisms of cancer promotion are known to be very different in each species. The strain-to-strain susceptibility for cancer in mice can vary a hundredfold, certain strains tolerating, with no apparent ill-effects, oestrogen doses that are many times higher than for other strains. Even if the gross response in two different species looks alike in the short term, the underlying mechanism which determines the long-term outcome is very likely different and can therefore lead to vastly different outcomes over the years. Incidentally, it would naturally be useless to perform SBT for a given species on cells or cell cultures belonging to a different species
6) Benefits of SBT for interested parties
The most obvious benefit would be consumer safety. SBT allows one to understand the mechanism by which a substance produces its adverse effects, which then allows one to forecast its long-term effects. By identifying cancer-promoting products, cancer prevention would be significantly boosted. As a result of science-based assessment of carcinogenic substances, we can estimate that cancer morbidity figures could be halved within the next three to five years. The reliable assessment of drug toxicity could save tens of thousands of lives a year. Neurotoxic substances (80% of insecticides are neurotoxic to insects: what about humans?) could be identified and removed from the market, preventing damage to the neuronal development of children ; according to the FDA, this could be the case with the insecticide rotenone. Detection and removal of endocrine proliferators would prevent both abnormal development of sex organs and of most hormone-dependent cancers (breast, ovary, prostate).
Improved consumer safety would result in the immediate alleviation of socio-economic costs resulting from diseases, rates for which are presently soaring in EU countries.
The benefits of SBT assessments for industry are many. SBT experiments (as mentioned above) take a few days on average, can be performed in large parallel screening set-ups (with various cell types or doses, for instance), are relatively inexpensive, easy to standardise and require tiny amounts of the xenobiotic (important in drug testing). The results are quantitative (large range of linear dose-response), reproducible and, most importantly, are reliable and valid for the species under investigation. Furthermore, understanding the mechanism of the adverse effect may allow in-house chemists to modify the xenobiotic and remove, or alleviate, its toxicity (with the help of Structure-Activity-Relationship models, for example) and improve the quality of the product and the image of the manufacturer! Since SBT tests are easily standardised and are independent of subjective parameters, the tests remain valid across political borders, which allows for unrestricted circulation of the SBT-tested goods among EU countries and abroad. These are definite scientific and economic advantages.
Whilst it is true that advanced technical skill is required for most of the SBT methods, and the requisite laboratory equipment is expensive, this would be more than counterbalanced by the relatively speedy scientific, economic and greatly improved public-health advantages.
SBT procedures also apply to other species and can therefore be used to assess environmental toxicities in any animal or plant species.
Since SBT procedures necessarily avoid 'model' species, they would also satisfy animal-welfare organizations.
Finally, implementing SBT methods would improve the image of the EU, both inside the EU countries (consumers would be grateful for better protection of their health) and outside the EU, as the Union could lead the way to effective improvement of environmental health issues worldwide.
7) How to proceed in view of the rapid and practical implementation of SBT in the EU
A strategy for the EU to hasten the introduction of SBT methods could be based on the following steps:
1. Elaborate a detailed SBT programme. To this end, create and fund a board of specialists. (Our organisations are ready to contribute their experience to this end.)
2. Fund and set up a European SBT pilot laboratory (eg, at the Joint Research Centre).
3. Fund and train SB Toxicologists. Organize a 6-8 month training course in the pilot laboratory for graduate or postgraduate fellows from all EU countries, with conferences and courses given by leading specialists in the field.
4. Encourage all EU countries to set up SBT pilot laboratories for the training, led by professional SB toxicologists, of more locally centred SB toxicologists.
5. Support industrial initiatives aimed at conversion to SBT methods.
6. Issue directives stating that all new products put on the market must have been tested as safe by SBT methods, namely, at the molecular and cellular level for products to which exposure is limited, and, in addition, at the tissue, organ (especially liver and kidney) and systemic levels for products to which exposure is significant (prescription drugs, food additives, pesticides etc). Products already on the market should be tested by SBT methods within three to five years, and those failing to pass the test should be withdrawn (perhaps with support for the development of safe equivalents).
(1) EC's White Paper Strategy for a future Chemical Policy,, published february 2001 by the European Commission, available on
(2) See EC's SCALE initiative (Science, Children, Awareness, Legal and Evaluation) and REACH system (Registration, Evaluation,Authorization of Chemicals), available from
(4) EC press release on environment and health, june 11, 2003
Latest news from Pro Anima Site in french
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7.V2005. gamma radiation:

9.V2005. rats, mouse, small animals and rodents, perfusion in veterinary institutions...
Hearth breaking and it doesn't matter the experiment what they performed (they could do it with NATURALLY already sick rat).

The point s, they ARE able to insert miniature needle in rat's veins, so the fact that vets say that small animals cannot be perfused or with nutrients when dehydrated because their vessels are too small is a lie.

9.V2005. go on ‘cool places’, then on left you have a choice: apart from what is written straight away. it seems after 'cool places' and 'clubs' clicks that there are quite a choice for us.

11.5.2005. brain dead and organ donation:

11.V2005. Humans choose their partners by scent:

11.V2005. chronic fatique cured

11.5.2005. domperidone impairs the heart beat:
'The drugs were already known to interfere with electrical activity controlling heartbeat.'
That is nerves that do that... the same nerves which made my heart beat so strong during exercise!
Vagus nerve, now I have higher than normal pulse, after one year taking of domperidone for gastroparesy.

11.5.2005. mercury erethism

12.5.2005. we need to extend her life: in coral

12.V2005. protiv rata:

12/5/2005. robot replicates itself :

13/5/2005.INdians help street dogs by feeding them:

13.V2005. New species of rat-like rodent found:

13.5.2005. UK woman freed after 8 weeks in prison for codein possesion:

13.5.2005. terrible occupators

13.V2005. hemp paper:

13.V2005. Coelho banned in Iran: and publisher fears for his life...

13.V2005. Hemp:

14.V2005. 400 bacteries types in the gut /Me call them kolonisators/:

16.V2005. Oats, avoine, ovas:


16.5.2005. its been explained why the CO2
sequestration in the oceans is a bad idea.

16.5.2005. kitovi i delfini i magnetizam i ljudski uticaj:

17.V2005. Ophtalmology laser:

18.V2005. Srbija and Montenegro in IMF report : worth reading

18.5.2005. Da se nasmejesh i zapitash:

18.V2005. Piano man:

18.V2005. Medical journal and pharmaceutical firms:

18.V2005. shoe step counter:

18.V2005. smallpox to live? Very dangereous:

18.V2005. smallpox: vaccination offered

18.V2005. Smoking in the children movies /has to be forbiden and put in adult movies etticquette infrot so people choose whether they want or not to watch/

19.V2005. speeding charge in UK, not Deutschland, luckilly :-)

19.V2005. Piano man:

19.V2005. Amazon forest:

19.5.2005. Very pollutant 4x4:

19.5.2005. human embryo cloned in UK:

19.5.2005. IVF 80 percent success rate: with pre-screening technique

19.V2005. GI diet good for health : and reduces possibility od getting diabetes and heart disease

19.V2005. Cities and population:

20.5.2005. Mass grave in Kosovo /who, how, trials?/ :

20.V2005. FBI information hacked:

20.V2005. handicap and AAH, polemique au quotidien:

21.V2005. Lake vanished within the night /interested in complete scientific explanation of this/ :


21.V2005. some chemical reaction: HCl and NaCl

21.V2005. Adult stem cells multiplying:

21.V2005. Diabetes and vegetarianisam:

21.V2005. Istorija starih ju republika:

22.5.2005. rollers:
I am for four wheels you can put on your shoes anytime...

wrote 22.5.2005. Will Israelis give me visa now to go on clinical trials for this? -diabetes cured by own liver cells in mice.

22.V2005. Palestinians ban hate cleric:

22.5.2005. onagre, primrose and preferably jojoba, huiles essentiels:

22.V2005. Body shop:

23.V2005. WiFi in the jungle. Hope he has a vegetarian holiday:

23.V2005. Vitamin B12 from bodybuilding site:

23.5.2005. Aids diagnosis:

23.V2005. BBC strike about jobs dissapearance :

23.V2005. Drink driving:

23.V2005. Time travel and Stephen Hawking:

23.V2005. nemam pojma odakle mi ovo:’origin definition of life’ The difference between the meaning of life and the phenomenon of life is clarified at the outset of the course, which then proceeds to discuss the topic of definitions in general and the definition of life itself. The process of defining life invokes various metaphysical and epistemic views. What are the objects, the processes and the phenomena that "life" refers to? What are the common features of these, and the special characteristics, which differentiate the animate from the inanimate? The course discusses the definitions suggested by notable biologists and philosophers -from Aristotle to Maynard Smith - examines their ontological and epistemological dimensions, and tries to unravel their implicit suppositions. Finally, the most common definitions of life at present - those based on heredity and on metabolism - are presented and analyzed. The course examines whether the definition of life is essential and whether it is possible. The issues of artificial life and the origin of life are also touched upon in this course.

24.V2005. millenium ecosystem assesment:

24.V2005. Adult stem cells help patients liver disease: Only thing is, not to put too much toxics (medicaments, alcohol...) in the body..

24.V2005. recycling plastics:

24.V2005. recycling facts:

24.V2005. recycling plastics links:

24.V2005. recycling, what can be recycled?

24.V2005. recycling:

24.V2005. IVF: tp://

24.V2005. Astma medicine: lekovi in high doses
25.V2005. vivisection debate in UK continues:

25.V2005. Organ donation and hamster virus:

25.V2005. Designer mouse questionned:
I suggest you read the BUAV's Designer Mice report, which is available on our website or via the link below. You should particularly note the section on alternatives from page 72 onwards.
If you find the whole report difficult to digest, there is an executive summary available.
Nicky Gordon
Science Officer BUAV, 16a Crane Grove, London N7 8NN, 020 7700 4888
Please visit or call 020 7700 4888 for further information about the work of the BUAV or to support our campaigns.

25.V2005. voda, water, H2O :

26.5.2005. Amsterdam cofee shop: /Me, just to ask to next year do not be smoked marihuanna and especially hashish as we need global warmin diminushion, and paper industry might need it, and seeds might be needed for next year’s hemp replacement in paper industry/.

26.V2005. heart disease and stroke : from bbc

26.V2005. In Slovenia: read the last paragraph, pls.

26.V2005. What happened?: congres for the water and environment u Parizu

26.V2005. bebe, babies:

27.V2005. Car toilet: how environmentally friendly? but great thing! read last paragraf /Me: it has other applications, not just in car usage/

27.V2005. Amazon, 30 years and now:

27.V2005. Scottish green school just south of Edinbourgh:

27.V2005. Beachers guide for Scotland:

27.V2005. What I sent to BBC: Respect,
It is my understanding that BBC heads want to suck 20% of the workers as there is money deficit. I have an idea which you may like to consider.
There are plenty people in the world that have TV channels provided by a cable company. In France we have Noos company where we could pay specially for some programmas if we wanna get them.
If you offer BBC 1-5 TV channels for couple of euros/month to cable companies they would put it in the offer and you could benefit. Although British international community may not be so large, there are other English and English-feel people who would be delighted to be able to obtain your great 5 channels abroad.
Please consider changing and expanding your policy in this international direction. All of us could benefit from it.
I do understand that BBCWorld and BBCPrime are already offered to worldwide audience, but their content cannot cover everything BBC produce and it is (must criticize you here) terribly sad that BBCPrime is often 1-2 years behind BBC from UK and BBCPrime repeat the same serials way too often (Bodges and Rogers, M.Parkinson, Hapiness, comedy programs are all repeated, MasterMind 1 year late...).
Peace and respect,

27.V.2005. This must be a joke or from TV and comp games: 24% of 16 year olds in Uk has weapons...

28.V2005. Nuclear weapons: . /Me:There are few pushups for annihilation of nuclear weapons existance. We should aime to do it soon, together with demilitarisation act which will have opposition we cannot wait, it should be done earlier/.

29.V2005. I forgot this clubbing link in A-dam: /It would be a paradise if everyone is clean and no drugs are there and just music makes you dance as if you are a kid..Because every narcotic influences brain and heart and makes it weaker, we do not need it in eternal life here/.

29.V2005. Interested in magic mushrooms? /Me: it would be great that life is so unstressed that we feel naturally like on one mushroom from the packet of few they give us in smart shops for one trip, that feel is only posible to get if personbelieves in life with money system on equal basis for all countries, then we would feel as if we see things more colourful and hear sounds more near/. Also, I believe that the dejstvo comes from the alkaloid in mushroom so its not appropriate for general usage. New Scientist and Scientific American I believe its called second journal have said it is researched as a pain reliever for cancer and neuropathy diagnosis so let it be researched, together with 2 to 3 micrograms doses of LSD alone is a good pain reliever on three days time, but acute, not chronicly to be taken...

29.V2005. Amsterdam Ibiza:

29.V2005. Cocaine testers are necessary not to put strain on organism with unpure form of the stimulant. It is sold here:

29.V2005. this is for cleaning as well, shouldn’t come too that if it is in pharmacies available cocaine under prescription in beginning:

29.5.2005. UK crippling Africa’s healthcare:

29.V2005. Computer game:

30.5.2005. Toxic ingredients in cosmetics:

30.V2005. Multiple sclerosis diagnosis:

30.V2005. iron, anaemia, hemoglobin, erythrocites:

30.V2005. Chronic fatigue syndrom diagnosis nearing the cure:

31.V2005 arthritis rheumatod and supplements:

31.V2005. diabetes and aminoacids that help:

31.5.2005. clubbing in Amsterdam:

1.6.2005. Humor a bit of:

1/6/2005. DEUG en Srbija:

1.VI2005. Yukos boss sentenced :

1.VI 2005. Two million Rusia teenagers illiterate: and there is big drug and health problems too. /Me: Srbija kids learn to read and write within the weeks. We should all switch to cjirilica, amin/.

1. VI 2005. In Israel are to be demolished eighty eight houses in ears Jerusalim: /Me: probably to make buildings and parks in code with global village kingdom.../

1.VI2005. Cantons of Swiss: /and a paralel with Jerusalim/:

2.VI2005. Vegan monthly:

2.VI2005. Nuclear waste in Sweden:/ Me: just how to send it all to Jupiter when we cannot influence the constant of radioactivity?/:

2.VI2005. flux of immigrants to Britain: from new EU member states

3/6/2005. Kylie’s bodyguards: telohranitelji /Me: so unnecesary if money is equal in all names and with maximum to spend on personal usage per month/

3.VI2005. Airport air pollution harms the memory of children:

3.VI2005. Beached whales saved in Australia:

3.VI2005. Serbians executed Serbs born to the muslim religion people video released: /Me: It is very important to note that Muslims, although after first World War we gave them big letter in the name are not Turks and are not nationality per se, only a religion based expressed people. Did not wanted to insult anyone/.

3.VI2005. signed ‘Mein kampf’ and other nazi memorabilia goes on sale: should be gone to the fire:

3.VI2005. Rats and pesticide toxicity nasledstvo:

3.VI2005. Cannabis spray: /Me: better way to ingesting it if alkaloid not toxic, THC alkaloid I suppose is in the spray. If still legal, should be given to Holand coffee shops instead of smoking cannabis, or better, to pharmacies where people addicted to cannabis smoke can come and close the cofee shops for purpose od smoking narcotics/:

3.VI2005. Eight year old kid has been beaten in London city for assumed witchcraft: really upsetting.

3.6.2005. g eight:

4.VI2005. Much better biased: report about serbian reaction on video tape

4.VI2005. Fifteen year old has been tagged in Scotland as he is an offender:

6.VI2005. rats expo:

6.VI.2005. From SFI /Scottish friends of Israel/ : university should never be demonised,,251-1644209,00.html

9.VI2005. Jobs control the heart:

9.VI2005. Fizika:

9.VI2005. Moulding and recycling plastics: 3dm worldwide

9.VI2005. Narcotic or stimulant? In few scientific magasines is recently being proposed that LSD has pharmakokinetic influence on brain of patients, therefore, those with unlegal usage of LSD should be stopped whilst is proving as a treatman for range of diseases but not all:

10.VI2005. Rats on BBC:

18.VI2005. Israel and Gaza have a sea barrier between them:

18.VI2005. good for everyone: when it becomes available...

18.VI2005. grow your own heart bypass:

18.VI2005. good friends prolong the life:

18.VI2005. smoking and fatness age body quicker:

18.VI2005. time travel, Ainstein, present and past:

18.VI2005. Bill Thompson about ebay, g8 freedom of speech on internet:

18.VI2005. Biometric data on passports sought by USA for other countries:

18.VI2005. Kosovo today:

19.VI2005. Sundeep:

19.VI2005. Drylands: eco assesment

19.VI2005. Nun killed in exorcism ritual: Should not been performed at all the rituals involving unvolontary subjects:

19.VI2005. Shoulder ramena:

19.VI2005. Milk and Parkinson disease diagnosis: /Me: Milk promotes growth in newborn children and it is less enzyme to digest it in humans within 4 years of age, therefore, thus the imperative to stop using the milk and dairy products is necessary to obtain the regular function of body as a grown up adult with all growth factors on place. Lactose in tablettes and other medicaments should also be avoided as this also might promote unwanted stimulative effect to unknown location in a body/:

19.VI2005. Milk and Parkinson’s disease diagnosis:

19.VI2005. Kokos coconut: /Me: apart from almonds as a staple diet for humanity to live eternally, it might be possible that coconut vrshi the same function in the body, ie, gives the good fats and infinitezimal number of carbohydrates therefore promoting the homeostazis by not promoting the insulin excretion/.

19.VI2005. Sugar and cancer diagnosis:/ Me: above staple diet first to cancer and diabetes diagnosis to be offered, I agree that sugar promotes hyperglycaemic spikes and growth factores in eyes, for examples are effect of high sugar in retinopathy diagnosis and in older people in general as have been using the high carbs food/:

19.VI2005. Chlorella: Mercola Me: Chlorella is one cell organism and thus the benefits from it but I am not sure if it is recommanded for all population in present form, may be genetically modified in controlled conditions into usable nutrients.

19.VI2005. Plastic food containers: and cancer risk, Mercola

19.VI2005. Dental teeth: Mercola

19.VI2005. Grains, vegetarian:

19.06.2005. Food labelling : /Me : an obligation worldwide only in supermarkets to be offered to be taken not imprinted on product so eco products and less paper and ink is in usage/ :

19.VI2005. Salt sodium electrolites: /Me: Salt is not a promoter of growth but acts as a medium in which skin grows, and fetus as well grows in a womb in a salty water, therefore it promotes a different range of problems than sugar supposedly as it acts within whilst sugar around and through nutritional system, through Vagus nerve we do not notice it apart from happines in beginning on the mouth plate. Noone would drink salty water when they swim in the sea, the same lays for sugary water as well, although it is more obvious the addiction to it/.

20.6.2005. Floods in England: global warming?

20.VI2005. Diabetes:

20.VI2005. recommended to me to check it out :

20.VI2005. Goedel incompletness theorem maths:

20.VI2005. FLT:'s_last_theorem.html

20.VI2005. Refugees:

20.VI2005. Debt relief Afrika and have your say:

21.VI2005. Pony: How far away is that place from Edinburg (animal help place)?

21.VI2005. Graduates after University relies on parents money: read the comments bellow the article...

21.VI2005. Chemistry and physics graduates earn most:

21.VI2005. Rat chewed cable and stop NZ mobiles and internet for the day ;-) , . I hope he survived as they often chew on stuff they want us to change habits off.

21.VI2005. Best freedom blogs:

21.VI2005. Teleporting over the internet: from nano - dust..

21.VI2005. Nanotechnology:

22.VI2005. IVF, low sperm count, abstinence:

22.VI2005. Genes help woman conceive after 45th year of age:

22.VI2005. EU carbon dioxide emissions rose:

22.VI2005. Arrest of human trafficers in Italia : so disturbing

22.VI2005. Foreign students in Scotland and jobs:

22.VI2005. Sugar subsidies, EU:

22.VI2005. Migration good for everybody : , therefore, viza requirements are past or are for everyone less /or more?/ the age of fourty /40/ year. For everyone should be needed viza in the world to travel in other country, or for noone should be needed viza at all in all parts of Earth, regardless of geografic position of birth and life, diagnosis and mother tongue. Let it make even simpler, as we are in the century of municipalities or mairie or opshtina na srpskom, every opshtina should forbid other opshtinas or mairie or municipalities in the world who cannnot approach without viza requirements, list them all the towns whose people, civil servants of those towns need special ordeal to come and vizit your town. AMEN.

22.6.2005. Bob Geldof and g8 live aid concert critics:

22.VI2005. Pollution in France, ozone:

222.VI2005. Hillary Clinton wants to become next president of North America :

22.VI2005. Freddie from Kenya refused UK viza to enter the country for treatmant. Do not think it is a silly joke as it isn’t, it really is forbiden for the just born infant to come as if he is a criminal and UK only place outside of prison where he cannot go as he serves a prison sentence in the Kenya... Am I clear? I avoid anger, but there are few subjects that are so out of date in the world, like visa, that I feel nausious to talk or mention them at all, but it is for majority of humankind so it must be sorted as soon as possible:

23.VI2005. from SFI, "Between the Lines "
From the Bicom site you can access the following news item
By Mark Ellis Foreign Editor
A SUICIDE bomber gasps in disappointment as 20lbs of explosive stashed in her pants fails to detonate.
Then in bewilderment she raises her head to heaven.
These unique CCTV pictures were taken at the Erez crossing between Gaza and Israel as Palestinian Wafa al-Biss made her martyrdom bid after being told to strip by border guards.
She was being allowed into Israel for treatment after being scarred in a cooking explosion. Afterwards Israeli officials let her give a TV interview to highlight the continuing terror threat despite a ceasefire.
Al-Biss, 21, said she had longed to be a suicide bomber since childhood, crying: "I believe in death." She then shakily blurted out: "I didn't kill anyone, will they forgive me?"

/Me: I must here say that I am more for giving to those people that grow in suicide rich communities all the thrills of extreme sports and install all possible extreme sports that could thrive there, like parachutism, waterflying and surfing, and so on... Hopefully the person can expect the same thrill in preparation for the sport as in the sport itself and what is even better, it can repeat it if it survives! Better than games on comp for sure. Hope that the girl is feeling better about her doings and whereabouts now/.

23.VI2005. Cholesterol and more:

23.VI2005. Diabetes:

23.VI2005. Cholesterol, ageing, heart disease : a quote: a quote... very important.
But if we know that vitamin C and glucose have similar chemical structure, what happens when sugar levels go up? They compete for one another upon entering the cells. And the thing that mediates the entry of vitamin C into the cells is the same thing that mediates the entry of glucose into the cells. If there is more glucose around then less vitamin C will be allowed into the cell, and it doesn't take much glucose to have this effect. A blood sugar value of 120 reduces the phagocytic index 75 percent.
/Me: Almonds and sesame do not have vitamin C in its structure at all, but they do have a weak glycaemic index value. Quorn also, I believe, do not have vitamin C as do the chick peas, please check it out, I have looked only into nuts. Very interesting, but there is a reaction /during anal sex/, when put on sesame seed oil, either no reaction at all for healthy people, or itching if there is a high sugar, check it out, please, but reaction I am interested in especially as we use cellulose rich paper for toalet cleansing. A hint: E.Coli lives near the beginning of the anal hole and its food is sugar but which one, glucose or sacharose?.../.

24.VI2005. Theology: of thelema
Please read, indeed I do agree with most of things except for putting the
main concepts of Winged Serpent to be Hadit and Horus as hawk headed
deity. I would put those main deities to be human-like, or allegoricaly
like some other indeed holy concepts, as both serpent and hawk are rodent
eaters and they are not able to control such hunger until, one day, we,
humans do not teach them otherwise (in beggining giving them veggy food
and afterwards bring them to evolve into herbivores).
But most of the other theology concepts are quite good.

23.VI2005. Diseases are a result of a lack of communication. There are certain things that your cells need to be healthy. If you learn nothing else today, you should know that everything is at the cellular and molecular level and we are nothing but a community of cells. We are a commune of cells; a metropolis of cells that have been given instructions to cooperate. Dr.Mercola

24.VI2005. Sailing on sunlight:

24.VI2005. Playing music whilst having paralysis: like Stephen Hawking the physicist, he got the computer adapted so he could perform. I would like something adapted so animals can perform too.

24.VI2005. Islam and vegetarianism:

24.VI2005. Islam and vegetarianism:

24.VI2005. Animal sacrifice in different religions: quote: Do your rituals involve animal sacrifice?
None of the initiation rituals of O.T.O. or ecclesiastical rituals of E.G.C. involve animal sacrifice in any way. No O.T.O. member is ever required by O.T.O. to perform or participate in animal sacrifice. However, O.T.O. takes no moral or religious stand against the practice of animal sacrifice, per se. Animal sacrifice is an ancient and legitimate religious tradition that has historically been practiced by many established religious systems, including Classical Paganism, Judaism, Islam, and many African and Afro-Caribbean religions. /Me: How to persuade all those people not to sacrifice animals I just wander? It is a sorrow invoked afterwards, not joy, its not possible that someone can enjoy meal afterwards/.

24.VI2005. A letter to a friend in Israel with heart clogging history: This article (attention, has 4 pages, on the end of each one you go on
next one) is very worth reading. Please, read it when you have time,
patience and concentration. The main point is that high insulin levels
actually are main reasons for heart disease. I have heard it before, and
the link between arteries clothing and high insulin is quite
Apart from few supplements he is suggesting, the main thing would be to
avoid animal-derived food and to have high /unsaturated from animals/ fat diet,
consisting mainly from huge amounts of all types of nuts (be careful as
some of them are ultra salted, try to find unsalted ones), olive oil and
olives (also take care about salt), and pumpkin, sunflower and all other
You should seriously aim to exclude any added sugar (saccharose, sucrose,
glucose, dextrose) in you diet as well as to diminish grains like potatoe,
wheat-productsm, rice is not so bad but not refined...
To literally live from huge vegetable salads with lots of nuts and seeds
and you could use organic eggs (but from two eggs you use just one yolk
and two whites kind of idea).
You also have there in Israel great vegetarien viennen schnicle and other
veggy steaks and, of course chick peas products and beans would cover you
cravings for meat products.
Avoid also juses and prefer still water.
You may want to give blood with your cholesterol, tryglicerides,
glycaemia, hba1c, thyroid, electrolytes and calcium and renal functions
check up now and then check them again in about a month or two to see how
better it should be. Israelis have great veggy alternatives and with huge amounts of vegetables
and nuts you should feel very, very good. Best wishes, and here is the link:

24.VI2005. Vegetarianism as seen from historic perspective:

24.VI2005. Vegetarianism and hinduism:

24.VI2005. Recycling in UK: /Me: we should all follow suit after Deutschland as they are top country in recycling methods/:

24.VI2005. Ecologic village for g8 summit: and not exactly generous villagemen...

24.VI2005. Pill for black-skinned people: or something else (patent extension)? /Me: pharmaceutical industries often find some requizite necessary for their pill still to be produced just from them, not to have patent available to other pharmaceutical firms who then produce the same pill for smaller price. The price should be always equal; that is first, especially to be given credit to people who formed the medicament. But to keep patent of medicament just for self is not good as they are /pharmacists/ in serve to humanity I believe/.

25.VI2005. Pulsar: from Nasa site

25.VI2005. Rhythms in stomack: ritmovi u stomaku /Me: it must always be observed as a problem in musical arrangement can show us the disease coming or source. Good to be put on Pendra like device if it can catch up the rhythms from within/.

25.VI2005; Electrogastrogram: gastroenterolog for stomach stomak

25.VI2005. Dyspepsia: other stomach stomak diagnosis and ibs also explained. IBS=irritable bowel syndrom.

25.VI2005. Unfairness: tsunami aid went to richest:

25.VI2005. Patents are bad for health: in brazil, they will start producing generic aids drug as the patented one is risk to public human health. well done.

25.VI2005. Billy Graham: wish him to heal. evangelist that is for love amongs the people.

25.VI2005. GM ban will continue in EU whilst UK voted for GM amidst public opposition to it:

26.VI2005. Clubs in Durham:

26.VI2005. Comment from my friend: This is very bad. Title: Iran loser blasts ‘illegal poll’:

26.6.2006. Iran poll result, world reaction and my friend comment on the end: Read this too - especially israels comments

26.VI2005. Usability from Bill Thompson: and a user interface that lets you control the music you're listening to by clicking your fingers in a particular place...

27.VI2005. Astrology data for Nikola Tesla:

27.VI2005. Foetus in foeto: parasitic conjoint twin


27.VI2005. Vegetarian omega 3 :

27.VI2005. Vitamin B3 : niacin

27.VI2005. Glastonbury festival :

28.VI2005. Astrology:

30.VI2005. Carbon sequestration, gas, hydrogen power plant:

30.VI2005. 90 year old Great Man: I just hope he won't continue with all 9-10 races in a day if he feels tired... Hope that he will listen to himself, not ego pumped by journalists. If he can just run as he does, that is sooo great.

30.VI2005. Assisted suicide:/Me: I am not for euthanasia in any form. It should be writen in our ‘carte Vitale’ wheter we are for experimental with our consent or without application of new ideas in a case of the disease with which we cannot perform in life as we once did. So better to try something radical then to simply give up to smal knowledge about cure or medicines that could ameliorate and bring back to homeostasis of the organism/:

30.VI2005. Gluconeogenesis: /Me: Am I the only one or with other recipients of DAFNE insulin system we have an augmentation of glycaemia after the influence of the insulin stops, ie, from somewhere gluconeogenesis is very active in us although it is not so active nor quick when we go low, in hypoglycaemia when we go there is no gluconeogenesis? Maybe only Actrapid type of insulin that is the only one identical to human should be without excipients like pesticides and hydrochloric acid or even salt, NaCl, or we should get the S.Cerevisiae made Actrapid with three aminoacids different, like for cow, but pure again insulin I suppose/:

1.VII2005. Papier chanvre: hemp paper, konopljin papir :

1.VII2005. Chanvre, hemp or konoplja :

1.VII2005. Nuclear :or renewable energy :

1.VII2005. Microsoft firm needs new software: to follow technology, 2020:

1.VII2005. Bill Thompson: internet tools to stay free

1.VII2005. Romania: to enter the Euro zone in 2012 ? /Me: the hole in law is that everyone of us can join the Euro zone as did the part of country Srbija i Montenegro joined in without a problem in a proportion it wanted, that is why I recomend to join in with French application of prices and money value of Euro, ie, minimum of wage for 35 hours work per week to be 1000 euros per month and that is how all of us can ‘glue’ to the Euro zone and French standard with just few changes of prices on the level of transport and import exported goods. Everything else would blossom from 1:1 ratio to Euro unit of money and French minimum of wage in Euros standard. 1000 euros per month comes from taxes paid workers on minimum wage, like person does cleaning in social hospitals and similar/.

2.VII2005. Polyunsaturated oils: olive, sunflower, canola, coconut...Mercola

3.VII2005. Pi-man, congrat: or if he could share his memorisation tips with us all...

3.VII2005. Cure for diagnosis of diabetes type one:

3.VII2005. Design for future:

3.VII2005. Kosovo north-west today:

4.VII2005. Toxicity of fluoride:

5.VII2005. Srbija voda /Serbia, water/:

5.VII2005. Voda i energija u Srbiji / Water and energy in Serbia/:

5.VII2005. Water scarce in France: 46 departments have restrictions on water usage. And where are that notices on buildings of Paris? Couldn't see.

5.VII2005. Only Gay in village story:

5.VII2005. Born under punches lyrics Talking Heads:

5.VII2005. Ingenieur de son formation:

6.VII2005. Wave power :

6.VII2005. Calorie calculator:

6.VII2005. Srebrenica: who did this and with which intentions, purpose?

6.VII2005. Metamfetamine overtaken cocaine in North America:/Me: this is a problem as amphetamins are very much toxic to the brain/:

6.VII2005. Formation professionnelle and remuneration en France:

6.VII2005. Formation et recherche d’emploi pour travailleurs handicapes :

6.VII2005. British embassy politics : racists!!!

7.VII2005. Journalism in America threaten by CIA:

7.VII2005. Pamplona BBC:

7.VII2005. G8, second day :

7.VII2005. Nuclear power plants more expencive in twenty years time than renewables:

7/7/2005. Statement claiming London attacks:

8.VII2005. G8 climate change draft jadan:

12.VII2005. Answer to conformal method question: Since I am myself is a beginner of Conformal Field Theory, I could only write this tiny intuitive beginning introduction for you which is as followed.
Conformal Field Theory, which has potential applications on the critical behaviour of systems at critical point where continuous phase transformation occurs. Approaching critical point, degrees of freedom of system are strongly correlated which would appear very hard to pursue theoretical analysis. Luckily, some symmetry can simplify the problem, for example, rotation symmetry reduce the Schordinger equation of Hydrogen atom to ordinary differential equation. A similar symmetry exists in critical phenomena in 2 dimention: it is called Conformal Symmetry.
Hope that does not decrease too much your interests.

16.VII2005. Wabe power:

16.VII2005. Eco-design of future cities:

16.VII2005. Kokain found in EU parliaments:

16.VII2005. Death in Pamplona:/Me: the PETA organises action around that time. Please read its words of wisdom about the terrible method of lowering standard of humanity/:

16.VII2005. Srebrenica:

16.VII2005. REACH, amendments:

17.VII2005. About aspartame: in minute amounts it influences people indeed, only they, as usual, didn't tell that.
I think you should cut it off. Please.
ps, will find those articles about aspartame toxicity. parkinson and alzheimer disease patients have more aspartame than people. aspartame is made in brain as a toxic by-product when brain works too much (like lactic acid which is made in you muscles if you overdo exercise). When aspartame is ingested through stomack it messes up with your digestive system, bloodstream and does nerve poisoning - its not good and makes more diseases than those they mentioned. DD. Rumsfeld owned aspartame company up till few years ago (!) and sold it to Monsanto (worst geneticly modified products making company).
Even though sugar is bad as well as it rises your insulin levels and brings accelerated ageing, oxidative stress and cardiovascular and nerve degenerative diseases, in this case I believe it is lesser evil than aspartame.

17.VII2005. Food llergy IBS link:

17.VII2005. Urgent-lets jump: rivers

17.VII2005. Salt and astma:;jsessionid=Cal8wI9T2lUGtFOIkqxFznBslTHIT0jWHh4CjUFAogIEWMRPtP5Y!-1535698990!-949856032!9001!-1 or

17.VII2005. Sugar and muscle eating body:

17.VII2005. American diabetic association chokes on its double talk:

17.VII2005. Some facts: about sugar. PS. see the references.

17.VII2005. Aldosterone adison disease adrenal:

17.VII2005. Millenium ecosystem assesment:

17.VII2005. Gluconeogenesis:

17.VII2005. Russia pipeline risk to Siberia wildlife:

17.VII2005. La vie en Montpellier: so where is better - on south or Paris? So sad, indeed - water wasteage.

17.VII2005. Global warming and vegetarianism:

18.VII2005. hp sales:

18.VII2005. Heat wave in south Europe:

18.VII2005. Pollution in utero:

18.VII2005. REACH no animal tests amendments :

20.VII2005. Urgent request: /Me: military plains should on daily basis go on places where they have to bring food. Amin/.

20.VII2005. RSPCA claims animal neglect rose by 90 percent: more than disturbing...

20.VII2005. Cows banned from eating hemp /they shouldn’t be banned from it/:

20.VII2005. Answer from a colegue student: But aren't we carnivores?
Our teeth show we are by evolution omnivorous... we have both incisor and canine teeth for tearing flesh and molars and premolars for 'grinding' seeds and other vegetable matter. However now we have (supposedly) developed a certain level of intelligence we should be able to make a conscious decision to adjust our diet according to the planet's resources and our personal nutritional requirements.

21.VII2005. Sheep mulesing in Australia and PETA actions:

21.VII2005. Cortisol adrenal sress hormone:

21.7.2005. Aldosterone adrenal gland: cortisol, mineralocorticoids

21.VII2005. Bird flu vaccine:

21.VII2005. Villi anathomy human:

21.7.2005. Nuts:,1523,84,00.html

22.VII2005. Concern about food crisis:

22.VII2005. Mezuzah, should everyone have it to welcome all arrivants:

23.VII2005. Egypt, please read all:

23.VII2005. Coconut oil, fat: It is good for thyroid. Indeed, in other article, Mercola states that the olive oil should be ok to use in salads and fresh, but when frying, because of the biochemistry degradation, the best is to use coconut.

23.VII2005. Vegetable juice:

23.VII2005. Caterpillar eats snails – evolution : only in hawaii. poor snails.

23.VII2005. ibm hackers without prison:


24.VII2005. Mercury should not be injected :

24.VII2005. Environmental toxins in water:

24.VII2005. Cholesterol and almonds:

24.VII2005. Comments on innocent guy shooting in London:

24.VII2005. Radioactive tracers triger airport security:

24.VII2005. This is the news I like to hear-hair:

24.VII2005. Water draught wetland birds decline:

24.VII2005. Evolution – speciation: /Me: Ljudi su pocheli sa specijacijom i to jednaki monetarni fond i sloboda kretanja treba da reshi. People started with speciation and equal money worldwide and freedom of movement has to solve this problem/.

24.VII2005. Aldosterone on google search:

24.VII2005. Kalium Potassium:,1525,10086,00.html

24.VII2005. Mineralocorticoids : adrenal

24.VII2995. Meat, artmeat, lab grown :

24.VII2005. Jason Matheny artmeso artmeat:

25.VII2005. Asil:

25.VII2005. Asil :

25.VII2005. Major cooperation between Israel, Jordan and Palestinian Authority :

25.VII2005. Mice danger to birds: /Me: both need to live/.

25.VII2005. Killed pigs carry deadly virus in China: /So do not kill them/:

25.VII2005. New HIV medicament hope: not communicating...

25.VII2005. Gut New Scientist protein:

25.VII2005. Evolution via memes:

25.VII2005. What an un-diplomacy: Godwin wants to marry Chelsea Clinton, but her father already 4 years avoids to give reponse.

26.VII2005. Nasha slova: quote: Kohonen, tip koji se bavi prepoznavanjem govora uz pomoć neuronskih mreža hvali se kako za svoje eksperimente koristi ispitivače koji govore nekim „manjinskim“ jezikom, koji je za njegove stvari posebno pogodan jer „je fonetski“. Interesantno da nije koristio srpski jezik -- a ni da ga mi za istu svrhu nismo koristili.

26.VII2005. Nasha slova /our letters/:

26.VII2005. Slova letters:


26.VII2005. Reciklirani papir danas recycled paper today :

26.VII2005. Srebrenica /this author was proposed for Nobel Peace prize/ :

26.VII2005. Kurir:

26.VII2005. Factory farm : why go vegetarian : why go vegetarian

26.VII2005. Ethical living from Guardian:,13437,1261568,00.html go veggy?

26.VII2005. Blinking eyes:

26.VII2005. Rectify, tourism, poverty: charitable organisations.

26.7.2005. World development movement: The three richest men in the world are wealthier than the 48 poorest countries combined. Policies that give increasing power to multinational companies. For every £1 of aid going into poor countries, multinationals take 66p of profits out.

27.VII2005. Viruses, bacteriophages, antibiotics: /Me: from OUSA environment forum/: Oh, they definitely are. Of particular benefit are the bacteriophages, which kill bacteria. Each one is specific to a particular bacterial strain. In Georgia in the former USSR they have been using phage for many years instead of synthetic antibiotics. One big advantage is that viruses evolve very rapidly, so as soon as bacteria evolve to be more infectious or more harmful, a phage virus evolves which can destroy it. Phage is at long last being considered in the UK as a possible solution to antibiotic resistance.
Now there's a good idea. I remember a lecturer many years ago going on at great length about how phages would be the new magic bullet and so on. Thirty years later it might finally get off the ground.

27.VII205. Cofee growers and sustainability: /Cofee is the second plant by using the pesticides for its growth/.

27.VII2005. Paper and phages /from OUSA forum/: I have also read that recycling actually uses less energy and water than making paper from scratch. Better is that recycling plants use oxygen bleaching than chlorine bleaching agents. But does it use more energy than driving heavy vehicles to plantations, cutting down trees, cutting up trees, pulping trees and transporting that? If you don't cart used paper to the recycling plant, what do you do with it? Bury it, compost it, anaerobically digest it or incinerate it. All those also require transportation, although in the latter two cases this will be offset by the energy produced.

27.VII2005. Hacker, whats this story about:

27.VII2005. Puffins in Scotland starve:

27.VII2005. Scottish water treatmant plant:

27.VII2005. Scottish economy:

27.VII2005. Renewables in Scotland:

27.VII2005. Pesticides near school cause of illness: environment pollution

27.VII2005. Irak war drama aired in north America: he did nypdblues

28.VII2005. New water restrictions in France in 60 departments:

28.VII2005. Huit nouvelles measures contre l’immigration irreguliere:

28.VII2005. Paper laser printers, OUSA : What about printer inks Jon? We talking about inkjet printers? If so, not the same ink as used in commercial printing. Laser printing is even worse - laser printers fuse plastic onto the surface of the paper.

29.VII2005. PV Sahara:,1895,441826,00.asp

29.VII2005. Insulin meta cresol:

29.VII2005. Toxicity:

29.VII2005. Beta-blockers and rats in terrible experiments:

30.VII2005. Loto and games on luck:

30.VII2005. Summer traffic in France: people want to go by car, but its bouche.

30.VII2005. Automobilistes se sont precipites samedi: ignorant les conseils... more, pls read both artices.

30.VII2005. I think that Severnprint claim to use environmentally-friendly inks,

30.7.2005. Solar:,1895,441826,00.asp

31.VII2005. Menopause hormone treatmants all cancerigens:

31.VII2005. Sugar and cancer:

31.VII2005. Canadians to suck plastic bag industry:

1.VIII2005. Flood in Mumbai – Panik causes deaths:

1.VIII2005. Beautiful spirit of Mumbai people: ...a bit like my countrymen...

1.VIII2005. Neuropathy treatment:

1.VIII2005. Trampoline accidents preventable:

1.VIII2005. Healyh mannekin:

1.VIII2005. Patents beer open source:

1.VIII2005. New Zealand pest control: /Me: better is to catch them all, sort them by sex and put them into some form of special zoos/.

1.VIII.2005. Fruit made wrinkle removers: face refreshment /Me: the best is white of frech hens unfertilised egg /and hen afterwards to get a retirement and life/ that makes strong the mask around the face or just clean the face with the piece of apple is great also for stopping the wrinkles/.

1.VIII2005. Diamants: /Me: diamants need to be stopped to be mined. There are plenty of them on the world, and there are artificial ways in making them/.

2.VIII2005. mindjushe:⊂=bijoux /Me: children should not be passed through ordeal of making holes into their ears without their consent and free will to do that. All silver and gold also has to be stopped minning as there is more than plenty in the world. Every person should have silver or golden /male female/ set of one spoon one fork and one knife from one of these precious metals to carry with him/her/.

2.VIII2005. mindjusha karat:

2.VIII2005. Dr.Mercola:

8.VIII2005. Gluconeogenesis, insulin resistance, diabetes :

3.VIII2005. free fatty acids, triglyceride, glucagon, gluconeogen, somatostatin:

3.VIII2005. C-peptide, fulminant, or acute diabetes:

3.VIII2005. C peptide

3.VIII2005. C peptide nerve repair :

3.VIII2005. C peptide: why is not still given to people on insulin?

3.VIII2005. Insulin like growth factor:

4.VIII2005. Dog cloned:

4.VIII2005. Intelligent design and evolution:

5.VIII2005. Food in Britain: although he obviously is not vegetarian but it seems likely he will become on as per his thinkin processus,,1541268,00.html

5.VIII2005. Salt:,2763,1540764,00.html

5.VIII2005. Alcohol consumption rise in Britain – supermarket survey:,2763,1541489,00.html

6.VIII2005. Happenings in Paris in august:

6.VIII2005. Lemonsound:

11.VIII2005. Astrologie : astrologie software free of charge, english french

13.VIII2005. News in Science – singing Saturn:

13.VIII2005. Cigarette, nikotin:

13.VIII2005. Paper :

13.VIII2005. Paper soy ink :

13.VIII2005. Levemir /Me:I believe this binding to albumin is toxic/:quote: Mode of action:Levemir® is engineered to bind to human albumin, which provides slow absorption and a prolonged action. The mechanism underlying this involves insulin self-association in the subcutaneous depot and albumin binding both in the subcutaneous tissue and in the circulation.13,14
To view an animation of Levemir®’s unique mode of action, click here
from novo nordisk for health care professionals.

13.VIII2005. Albumin: ; bovine albumin: ; albumin and glucose: /from here I believe it is toxic in insulin injections/.

13.VIII2005. In Ultratard:

13.VIII2005. Ultratard zinc chloride:

14.VIII2005. Hydrogen controversy :

14.VIII2005. Tourisam I was talking about /for French in this case, Brits have similar offers/: dominican republic- 9 days, flights, bad and food all day, ie, all inclusive for 390 euros!

15.VIII2005. Weather forecasting cloud formation /more accurate/:,,176-1734227,00.html

15.VIII2005. gm Mercola:

15.VIII2005. Ulcetarive collitis – probiotic bacterias good : and here is the original

16.VIII2005. Solar energy:


16.VIII2005. Paris turist :

17.VIII2005. Swimmer with diabetes swam Lamanche :

17.VIII2005. Children’s from exhaust fumes cancer risk:

17.VIII2005. Artificial meat BBC version:

17.VIII2005. Insulin protein:

17.VIII2005. Diabetes and leptin from Mercola : prevent alzheimer’s diagnosis:

18.VIII2005. Non Alcoholic fat liver disease:

18.VIII2005. Solar energy:

18.VIII2005. Physics web:

18.VIII2005. Eyes cataract: steroids can cause it- so too big stimulation of adrenal glands (by salt, glycemy spikes and stress, my hypothesis) can develop cataract.

19.VIII2005. hostels:

19.VIII2005. Insulin pumps in UK:

19.VIII2005. Insulin is still produced in diabetes type 1, cure is near!

19.VIII2005. Diabetes cure forum:

19.VIII2005. Skuba diving and diabetes :

19.VIII2005. Allergy to insulin:

19.VIII2005. Diabetes:

19.VIII2005. Artificiam pancreas works :

19.VIII2005. A quote genetics included: Factors that may increase the incidence of Type 1 diabetes include:
I. The disease has strong HLA associations, with linkage to the DQA and B genes, and it is influenced by the DRB genes These HLA-DR/DQ alleles can be either predisposing or protective. DR3 and DR4 increase the incidence, DR2, decreases the incidence
II. Most type 1 diabetes is characterized by the presence of islet cell, GAD, IA-2, IA-2ß, or insulin autoantibodies that identify the autoimmune process that leads to ß-cell destruction
III. Markers of the immune destruction of the ß-cell include islet cell
autoantibodies (ICAs), autoantibodies to insulin (IAAs),
autoantibodies to glutamic acid decarboxylase (GAD65), and
autoantibodies to the tyrosine phosphatases IA-2 and IA-2ß

19.VIII2005. Testing blood without the blood giving:
not just for diabetes, for everything!!

19.VIII2005. Green products in UK:

20.VIII2005. Elixir of life BBC:

20.VIII2005. Eye, cataract:

20.VIII2005. Trombe-Michel walls instead of air conditioning systems.

2°.VIII2005. Aligator in LA: carlito and harbor park harry is his nickname

20.VIII2005. Srbija 2005? I really do not like Matt Proger's spirit of reporting about Srbija, but check this out:

20.VIII2005. Global Village. Word was created...

21.VIII2005. Club Vinyl Paris:

22.VIII2005. Srpska astrology: astrologija

31.VIII2005. A book on hemp paper: (on the bottom of this page are more useful links you can check out);

31.VIII2005. More antiageing gene:

31.VIII2005. CO2 increase mass extinction link found:

31.VIII2005. Major ozone loss over Antarctica:

31.VIII2005. Environment poverty link:

31.VIII2005. Climate change Scotland chaos:

1.IX2005. Trafford language conservation project:

1.IX2005. Soya heart:

2.IX2005. Water scarce in France:

3.IX2005. Boris Mezga Comfort Fit:

3.IX2005. Social policy : Europe EU left

3.IX2005. Diabetes in UK : 2 million people, diagnosed, more undiagn.

3.IX2005. Vegan:

3.9.2005. Poor in hurricane Katrina /Me: it is better to call the huriccanes by letters and numbers not by names of people/:

3.IX2005. Urgent solar market: energy

3.IX2005. Sugar South Africa:

3.IX2005. US, global warming, hurricane, CO2:

3.IX2005. Fertility couples, alcohol, cigarettes:

3.IX2005. diabetes cure:

4.IX2005. Motivational speaker : diabetes :

4.9.2005. Mercury:

4.IX2005. Acidic alkaline foods:

4.IX2005. All soldiers should learn to be rescue workers:

4.IX2005. 3rd blaze woman gave birth at scene at Paris:

4.IX2005. GP doctors payslips in Europe 2005:

4.IX2005. Alzheimer diagnosis:

4.IX2005. China carbon sequestration plans : energy

5.IX2005. Situation economique chez Francais :

5.IX2005. Be optimist !


5.IX2005. Post Katrina opinions:

5.IX2005. 65 Year old and hip replacement:

5.IX2005. Stem cells /Me: only adult stem cells comes into considerationa as well as saved umbilical cords for those children that had them. It might be possible that ther are both child’s and mother’s adult stem cell in umbilical cord, be careful and ispitaj, check it out/:

6.IX2005. Emergency pet ambulance service launched in Scotland:

6.IX2005. Lakmus test ratnih zlochinaca of war criminals:

6.IX2005. School for American soldiers in Srbija:

6.IX2005. Double nationalship for Hungarians:

7.IX2005. Extasy 50 pence: extasy 50 pence... /Me: all synthetic drugs are deadly for our brain more than drugs from plants or fungi therefore they should be really forbidden. Extasy as well, it belongs to synthetic drugs and is too toxic for the brain in such amounts it is given for feeling good on parties. Third day after extasy using you can feel depressed as synaptic nerves are used too much three days earlier/.

7.IX2005. Smoking and eyes:

7.IX2005. Mobile phones:

7.IX2005. Mercola :

7.IX2005. Detergents, light bulbs, electricity, energy :

8.IX2005. Forced evacuation after hurricane chaos:

8.IX2005. Sugar cakes Mercola:

8.IX2005. Car accidents prevention gadget :
8.IX2005. More about sugar from Mercola :

8.IX2005. Diabetes levemir:

8.IX2005. Levemir albumin binding :

8.IX2005. Solar 750 kWh/y per kWp installed 10 m2 :

8.IX2005. Global Iration:

8.IX2005. Embryo with two mothers :

9.IX2005. Posthurricane premature babies alive:

9.IX2005. Rats in Nicaragua:

9.IX2005. Cleaning products reach baby /Me: thats why only Malki Dead Sea shampoo that has six ingredients is worth for bathing... without parfume is possible to make it/:

9/9/2005. Alzheimer diagnosis:

9.IX2005. Climate food crisis :

9.IX2005. Warmer soils climate worry:

9.IX2005. Peat fires increase global warming:

9.IX2005. Pic of global warming:
see side pic link as well

9.IX2005. See side links as well:

9.IX2005. BBC gives few songs to remixers:/Me:everyone should learn to dj/:

9.IX2005. Free access to research:

9.IX2005. Save Kazaa from internet piracy claims:

9.IX2005. Celebrities in hurricane chaos help:

9.IX2005. Animal insulin lantus:

9.IX2005. Free fatty acids gluconeogenesis :

9.IX2005. Lights in the sky should not be practisied often:

11.IX2005. Pets after hurricane chaos: animals... one hamster saved only.

11.IX2005. PETA helps animals after hurricane chaos:

12.IX2005. Nudism becomes popular: /Me: It is normal that nudisam is not illegal as the people from the different tribes in the world have custom to walk barefooted and naked, so we can imitate them or look up to them inb our municipalities, don’t we? Its a great pleasure to be naked in the town/.

12.IX2005. Inhaled insulin within a year in UK: /
see the complaints in article.

12.IX2005. Solar pv cost British bp:

12.IX2005. Ecologie, animaux:

13.IX2005. Metabolism of nonglucose sugars :

13.IX2005. Glucose and vitamin C influence on cancer:

13.IX2005. Lungs: should consider stopping smoking zbog lung disease risk


14.IX2005. No safe treshold for trans fatty acids:

15.IX2005. emf: maybe this could be the reason behind 'western tiredness syndrome'.

15.IX2005. Mobile phones emf rf: radio frequency

15.IX2005. Party scene Netherlands:

16.IX2005. Inhibitor of cancer development: Vegetarian food mainly consisting of beans, nuts and cereales - full of proteins and good glucides and fat anyway.

17.IX2005. Vasectomy film on internet /Me: although I agree that reversible vasectomy is the best way of child protection measures, I do am for the couples to have more kids, therefore, I am not recommanding any protection amongst married ones, and real love is that when couple marry/:

17.IX 2005. Should be Dutch fertility and no abortion ship:

17.IX2005. Global warming = bigger hurricanes:

17.IX2005. 60th UN Summit: I day:

17.IX2005. Hacking hacker hate from the court:

17.IX2005. Stolen Rembrant work recovered:

17.IX2005. E bay to buy skype:

17.IX2005. Hawking’s paradox:

17.IX2005. Switch to digital TV in UK iminent? Within three years:

17.IX2005. Srbija and Kosovo: see the tone and wording

17.IX2005. Australia diabetes forum pump: to choose 1 or 2? reflexology:,_Novo_Nordisk_and_Aventis_

19.112005. Acoustic energy loudspeakers:

21.IX2005. SOS handikap services:

27.IX 2005. Association for blind diagnosis in Srbija:

27.IX2005. Fonetik Braj letters: *

27.IX2005. FOE:

28.IX2005. diabetes 2 :

28.IX2005. Dawn phenomenon in diabetes :

28.IX2005. Cortisol:

29.IX2005. Airlines in carbon dioxide paying sheme :

29.IX2005. Arctic melting fast: 4th consec. year.

29.IX2005. Health disease genetic fingertip:

29.IX2005. Poverty:

29.IX2005. Less than hundred dollars computer for developing nations:

30.IX2005. Master in Jussieu:

30.IX2005. Liers brain different: how then lay-detector would work?

30.IX2005. Music instrument: learning good for heart

30.IX2005. Net control dispute:

30.IX2005. Night 50-way Skydive:

3.X2005. Again about pulses: veggy food=cancer prevention

4.X2005. Cancer diagnosis and spirit de vivre:

4.X2005. Even she succeded in stopping smoking :

4.X2005. Flies in Britain to double in population:

4.X2005. Journal applied ecology:

4.X2005. Rat medicines and travel: quote: oor little one... my Oliver never seemed in pain when this happened to him.
I certainly do keep a lot of things on hand for "just in case" with my rats.
I've got polysporin ear/eye drops, Quick Stop, Pedialyte, Ivermectin,
syringes, a stethoscope, nutrical. And I'll add whatever else I think
may help.

4.X2005. Very, very old dead rat: /Me: what happened to him and is it possible to clone him?/:

5.X2005. Fact: In France it was killed almost a miliard birds in the year 2004:

5.X2005. Pharmacy cancer drug needs approval quicker:

5.X2005. Hair issues in Africa: /Me: Africa should do Afrikan Union like European Union model and glue its money to the Euro and in proportion to French system of goods and minimum wage, do the social system like French with CAF, CNASEA,, Formation Continue, cours municipal d’adultes, CNED and so on, on all Afrikan level/.

5.X2005. Nobel price for ulcer bug:

5.X2005. Fertility India surrogate mum, single father:

5.X2005. Euthanasia, vets, suicide:

5.X2005. Fetal DNA in mother’s blood test :

5.X2005. Alcohol, fertility:

5.X2005. Quantum optics Physics Nobel prize:

5.X2005. J.K.Rowling Harry Potter 300 million books sold:

6.X2005. Animals hit by global warming:

6.X2005. Travel, Moroccans killed near Spanish border: 'internal investigation' /Me: every investigation in the world should be external and open to public as the Investigation Police is funded from public money/:

7.X2005. Vegan congress:

7.X2005. Confession of former sugar addict:

7.X2005. Veggy vegan the China study:

7.X2005. Vegan dog of 27 years:
/Me: on rice and lentils, every day different/.

7.X2005. Veggy life promoters: new research on nutrition and health
eating to live
soy-miracle or poison?
heart attack prevention
eating with compassion

7.X2005. Researchers Identify the 20 Most Antioxidant-Rich Foods:
1. Red beans 2. Wild blueberries 3. Red kidney beans 4. Pinto beans 5. Cultivated blueberries 6. Cranberries 7. Artichokes 8. Blackberries 9. Prunes 10. Raspberries 11. Strawberries 12. Red delicious apples 13. Granny Smith apples 14. Pecans 15. Sweet cherries 16. Black plums 17. Russet potatoes 18. Black beans 19. Plums 20. Gala apples. Source: Journal of Agricultural Food Chemistry, June 2004

7.X2995. Warm waters fuelled hurricane:

7.X2005. Astronomy for Astrology:

8.X2005. Hemp paper printing:

8.X2005. Kosovo:

8.X2005. 4x4 health warnings urged :

8.X2005. Serb Srebrenica: executors of video tape charged:

8.X2005. Greece refuses to refuel American boat:

10.X2005. Parisbouge, evenings out in Paris:

11.X2005. Nobel economie:

11.X2005. Enviromental refugees earthquakes:

11.X2005. Earthquake prediction:

19.X2005. A chatbot can turn nasty by learning from people:

28.X2005. Azbestos: to be recognized and treated that azbestos caused disease.

8.XI2005. Five star hotel opened in Afganistan: 250$ per night

8.XI2005. MS diagnosis medicament hope:

8.XI2005. Happy marriage fights off flu:

9.XI2005. Green technology for satellite launching:

9.XI2005. Unclear, vivisection done, protein and glucose production:

9.XI 2005. Energy demand projected to soar:

9.XI2005. Energy VOC and NOx to be catched from petrol stations:

9.XI2005. Children education:

9.XI2005. Drunken elks in Sweden:

9.XI2005. Elks and bicycle: it seems those animals are quite cute criters that love roses and humans?

12.XI2005. Some animals have problems with expressing the anal gland, it might be food related:

14.XI2005. Huge investment in renewable energies:

14.XI2005. Alaska drilling suspended for now:

14.XI2005. Lactic acidosis:

15.XI2005. Happiness:

16.XI2005. Energy production diminishes in Britain:

16.XI2005. REACH:

16.XI2005. Cannabis medicament allowed in UK for nerve pain for MS diagnosis:

16.XI2005. UK’s acid rain:

16.XI2005. Gazeous water heats the EU climate:

16.XI2005. Universal time leap second agreement postponed:

16.XI2005. Control of the net and fairer internet summit:

16.XI2005. Internet high speed college network:

16.XI2005. Air pollution:

16.XI2005. Salt and Natrium /sodium/ :

16.XI2005. Medical notes:

16.XI2005. Scottish workoholics do not use all holiday days:

16.XI2005. Malaria vaccine works:

17.XI2005. Cancer, electrons, radiation:

19.XI2005. BBC links:

19.XI2005. dalai Lama and other stuff:

19.XI2005. About Donald Watson, pls read all:

19.XI2005. Children in need, BBC English coverage:

21.XI2005. Singing clubs and memory improvements:

22.XI2005. Thats how Paul and me lost weight. We cut on wheat
products, reduced all other grains (see the article),
and replaced it with lentils, chick peas and all other
types of beans and huge amounts of vegetables...

22.XI2005. Vegetarisme, alimentation, wiki books:égéta*isme:Alimentation

23.XI2005. Global warming, Siberia burning fossil fuels:

23.XI2005. Plastic surgery facelift:

23.XI2005. Blood pressure:

23.XI2005. Fossil fuels taxation on avions, French initiative:

24.XI2005. Music production Paris cours:

25.XI2005. Stem cells- placenta :

26.XI2005. False sugars:

26.XI2005. Diagnostic radiology :
sound, waves, imaging

26.XI2005. Radio frequency :

28.XI2005. Sans domicile fixe, SDF:

29.XI2005. Hospitals :

29.XI2005. Schools and immigration in France:

29.XI2005. Nutrition, folic acid:

29.XI2005. Artificial pankreas, diabetes:

30.XI2005. Heart palpitations, pulse, diabetes:

30.XI2005. Heart pulse pvc:

1.XII2005. Chinese astrology:

1 comment:

joni laleet said...

There are rhythmic ideas which sometimes only work up to a point. In writing there are moments when it just comes off the page, it's not just a collection of notes.